WO2009133059A3 - Nanofiber matrices formed from electrospun hyperbranched polymers - Google Patents

Nanofiber matrices formed from electrospun hyperbranched polymers Download PDF

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Publication number
WO2009133059A3
WO2009133059A3 PCT/EP2009/055045 EP2009055045W WO2009133059A3 WO 2009133059 A3 WO2009133059 A3 WO 2009133059A3 EP 2009055045 W EP2009055045 W EP 2009055045W WO 2009133059 A3 WO2009133059 A3 WO 2009133059A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrospun
hyperbranched polymers
matrices formed
nanofiber matrices
electrospinning
Prior art date
Application number
PCT/EP2009/055045
Other languages
French (fr)
Other versions
WO2009133059A2 (en
Inventor
Matthias Seiler
Axel Kobus
Mark A. Mchugh
Stefan Bernhardt
Bernd Glöckler
Rolf Schneider
Henning Marckmann
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of WO2009133059A2 publication Critical patent/WO2009133059A2/en
Publication of WO2009133059A3 publication Critical patent/WO2009133059A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85—Polyesters
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
    • D04H1/4382—Stretched reticular film fibres; Composite fibres; Mixed fibres; Ultrafine fibres; Fibres for artificial leather
    • D04H1/43838—Ultrafine fibres, e.g. microfibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/005—Hyperbranched macromolecules
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D01D5/0023—Electro-spinning characterised by the initial state of the material the material being a polymer melt
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D01D5/003—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00—General methods for the manufacture of artificial filaments or the like
    • D01F1/02—Addition of substances to the spinning solution or to the melt
    • D01F1/10—Other agents for modifying properties
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/88—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
    • D01F6/92—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds of polyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

Abstract

A nanofiber matrix comprising an active agent suspended or enmeshed in fibers formed by the electrospinning of one or more hyperbranched polymers can be used in cosmetics, drug delivery and for the growth of cells. The process of electrospinning the hyperbranched polymer solution is carried out without an added solvent or with a solvent and a compressed gas.
PCT/EP2009/055045 2008-05-02 2009-04-27 Nanofiber matrices formed from electrospun hyperbranched polymers WO2009133059A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7152108P 2008-05-02 2008-05-02
US61/071,521 2008-05-02

Publications (2)

Publication Number Publication Date
WO2009133059A2 WO2009133059A2 (en) 2009-11-05
WO2009133059A3 true WO2009133059A3 (en) 2009-12-30

Family

ID=41171159

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/055045 WO2009133059A2 (en) 2008-05-02 2009-04-27 Nanofiber matrices formed from electrospun hyperbranched polymers

Country Status (1)

Country Link
WO (1) WO2009133059A2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE477291T1 (en) 2005-10-25 2010-08-15 Evonik Degussa Gmbh PREPARATIONS COMPRISING HYPERBRANCHED POLYMERS
JP5295943B2 (en) 2008-12-26 2013-09-18 花王株式会社 Nanofiber sheet
JP5666837B2 (en) * 2010-06-29 2015-02-12 花王株式会社 Nanofiber sheet
CZ201124A3 (en) 2011-01-17 2012-06-13 Elmarco S.R.O. Carrier for oromucosal, especially sublingual application of physiologically active compounds
WO2013035072A1 (en) * 2011-09-08 2013-03-14 Vile Glenn Bioactive nanofibres
DE102012200907A1 (en) 2012-01-23 2013-07-25 Evonik Industries Ag Method and absorption medium for absorbing CO2 from a gas mixture
EP2644191B1 (en) 2012-03-30 2016-08-03 Universitat Politécnica De Catalunya Nonwoven membrane as a drug delivery system
DE102012207509A1 (en) 2012-05-07 2013-11-07 Evonik Degussa Gmbh Method for absorbing CO2 from a gas mixture
GB2504996A (en) * 2012-08-17 2014-02-19 Univ Keele Embryonic stem cell culture method
GB2536169B (en) 2013-12-02 2020-07-08 Vladimirovich Bovin Nicolai Functionalizing nanofibres
DE102014004258A1 (en) * 2014-03-19 2015-09-24 Bauerfeind Ag Fibers and yarns with occlusion function
CN104032381B (en) * 2014-06-06 2016-08-24 浙江大学 Electrostatic spinning prepares hyperbranched polyethylene fiber and the method with carbon nano tube composite fibre thereof
DE102015212749A1 (en) 2015-07-08 2017-01-12 Evonik Degussa Gmbh Method for dehumidifying moist gas mixtures
CN105506861A (en) * 2015-11-27 2016-04-20 苏州大学 Natural colored nanofiber membrane preparation method
ES2579161B2 (en) * 2016-03-08 2017-03-28 Universidad De Las Palmas De Gran Canaria Aloe Vera hybrid nanofibers
EP3257568B1 (en) 2016-06-14 2019-09-18 Evonik Degussa GmbH Method for the removal of moisture from moist gas mixtures by use of ionic liquids
DE102016210484A1 (en) 2016-06-14 2017-12-14 Evonik Degussa Gmbh Method for dehumidifying moist gas mixtures
EP3257843A1 (en) 2016-06-14 2017-12-20 Evonik Degussa GmbH Method of preparing a high purity imidazolium salt
DE102016210478A1 (en) 2016-06-14 2017-12-14 Evonik Degussa Gmbh Method for dehumidifying moist gas mixtures
DE102016210483A1 (en) 2016-06-14 2017-12-14 Evonik Degussa Gmbh Process and absorbent for dehumidifying moist gas mixtures
DE102016210481B3 (en) 2016-06-14 2017-06-08 Evonik Degussa Gmbh Process for purifying an ionic liquid
CN106754367B (en) * 2016-12-12 2019-06-21 吉林大学 The method for carrying medicine cell climbing sheet is prepared by electrostatic spinning
WO2020016623A1 (en) * 2018-07-14 2020-01-23 Somaye Akbari Antibacterial nanofibrous layer

Citations (3)

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US6379683B1 (en) * 1999-03-02 2002-04-30 L'oreal Nanocapsules based on dendritic polymers
US20060240110A1 (en) * 2005-03-31 2006-10-26 Kiick Kristi L Multifunctional and biologically active matrices from multicomponent polymeric solutions
US20080018015A1 (en) * 2003-12-23 2008-01-24 Mchugh Mark Method of Producing Fibers by Electrospinning at High Pressures

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6379683B1 (en) * 1999-03-02 2002-04-30 L'oreal Nanocapsules based on dendritic polymers
US20080018015A1 (en) * 2003-12-23 2008-01-24 Mchugh Mark Method of Producing Fibers by Electrospinning at High Pressures
US20060240110A1 (en) * 2005-03-31 2006-10-26 Kiick Kristi L Multifunctional and biologically active matrices from multicomponent polymeric solutions

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KENNETH E. GONSALVES ET AL.: "Biomedical Nanostructures", 8 October 2007, JOHN WILEY & SONS, XP002552143 *
MCKEE M G ET AL: "Electrospinning of linear and highly branched segmented poly(urethane urea)s", 10 March 2005, POLYMER, ELSEVIER SCIENCE PUBLISHERS B.V, GB, PAGE(S) 2011 - 2015, ISSN: 0032-3861, XP004774409 *
UHRICH K: "Hyperbranched Polymers for Drug Delivery", 1 December 1997, TRENDS IN POLYMER SCIENCE, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, PAGE(S) 388 - 393, ISSN: 0966-4793, XP004098786 *

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