WO2009130712A3 - Controlled release pharmaceutical compositions of trospium - Google Patents

Controlled release pharmaceutical compositions of trospium Download PDF

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Publication number
WO2009130712A3
WO2009130712A3 PCT/IN2009/000245 IN2009000245W WO2009130712A3 WO 2009130712 A3 WO2009130712 A3 WO 2009130712A3 IN 2009000245 W IN2009000245 W IN 2009000245W WO 2009130712 A3 WO2009130712 A3 WO 2009130712A3
Authority
WO
WIPO (PCT)
Prior art keywords
trospium
controlled release
release pharmaceutical
pharmaceutical compositions
pharmaceutically acceptable
Prior art date
Application number
PCT/IN2009/000245
Other languages
French (fr)
Other versions
WO2009130712A2 (en
Inventor
Raghu Rami Reddy Kasu
Raghavendra Vishwanath Nayak
Subhasis Das
Vijaya Kumar Thommandru
Original Assignee
Lupin Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Limited filed Critical Lupin Limited
Publication of WO2009130712A2 publication Critical patent/WO2009130712A2/en
Publication of WO2009130712A3 publication Critical patent/WO2009130712A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A controlled release pharmaceutical composition comprising Trospium or its pharmaceutically acceptable complexes, salts, polymorphs, hydrates, solvates, enantiomers or racemates, or mixtures thereof; one or more hydrophobic release controlling agent(s) and other pharmaceutically acceptable excipients.
PCT/IN2009/000245 2008-04-22 2009-04-22 Controlled release pharmaceutical compositions of trospium WO2009130712A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN746KO2008 2008-04-22
IN746/KOL/2008 2008-04-22

Publications (2)

Publication Number Publication Date
WO2009130712A2 WO2009130712A2 (en) 2009-10-29
WO2009130712A3 true WO2009130712A3 (en) 2010-03-11

Family

ID=40941726

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2009/000245 WO2009130712A2 (en) 2008-04-22 2009-04-22 Controlled release pharmaceutical compositions of trospium

Country Status (1)

Country Link
WO (1) WO2009130712A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050191351A1 (en) * 2003-11-04 2005-09-01 Shire Laboratories, Inc. Once daily dosage forms of trospium
US20060210625A1 (en) * 2003-11-04 2006-09-21 Shire Laboratories, Inc. Sustained release of positively charged pharmacologically active molecules from a matrix containing polymers with polarized oxygen atoms
EP1880718A1 (en) * 2006-07-10 2008-01-23 Dr. R. Pfleger Chemische Fabrik GmbH Pharmaceutical preparation for oral administration with controlled drug release in the small intestine colon and process of prepartion thereof
WO2009052353A2 (en) * 2007-10-17 2009-04-23 Dr. Reddy's Laboratories Ltd. Trospium pharmaceutical formulations

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050191351A1 (en) * 2003-11-04 2005-09-01 Shire Laboratories, Inc. Once daily dosage forms of trospium
US20060210625A1 (en) * 2003-11-04 2006-09-21 Shire Laboratories, Inc. Sustained release of positively charged pharmacologically active molecules from a matrix containing polymers with polarized oxygen atoms
EP1880718A1 (en) * 2006-07-10 2008-01-23 Dr. R. Pfleger Chemische Fabrik GmbH Pharmaceutical preparation for oral administration with controlled drug release in the small intestine colon and process of prepartion thereof
WO2009052353A2 (en) * 2007-10-17 2009-04-23 Dr. Reddy's Laboratories Ltd. Trospium pharmaceutical formulations

Also Published As

Publication number Publication date
WO2009130712A2 (en) 2009-10-29

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