WO2009122114A1 - Apparatus for monitoring a human or animal subject's bodily function - Google Patents

Apparatus for monitoring a human or animal subject's bodily function Download PDF

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Publication number
WO2009122114A1
WO2009122114A1 PCT/GB2008/001144 GB2008001144W WO2009122114A1 WO 2009122114 A1 WO2009122114 A1 WO 2009122114A1 GB 2008001144 W GB2008001144 W GB 2008001144W WO 2009122114 A1 WO2009122114 A1 WO 2009122114A1
Authority
WO
WIPO (PCT)
Prior art keywords
eye
subject
light
eyepiece
lens
Prior art date
Application number
PCT/GB2008/001144
Other languages
French (fr)
Inventor
Christopher Glynn
William Neville Heaton Johnson
Original Assignee
H-Icheck Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H-Icheck Limited filed Critical H-Icheck Limited
Priority to PCT/GB2008/001144 priority Critical patent/WO2009122114A1/en
Publication of WO2009122114A1 publication Critical patent/WO2009122114A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6898—Portable consumer electronic devices, e.g. music players, telephones, tablet computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0013—Medical image data

Definitions

  • This invention relates to apparatus for monitoring a human or animal subject's bodily function in vivo via the subject's eye.
  • WO02/071932 discloses an improvement to this apparatus in which a pupillometer is used to assist in aligning the apparatus with the pupil of the eye and WO2006/079824 discloses a further improvement in which pulsed input light is used and the returning light recorded at a timing such that the majority of the light recorded is diffuse light, ie the eye is used as an integrating sphere whereby the signal to noise ratio is improved.
  • a pupillometer is used to assist in aligning the apparatus with the pupil of the eye
  • WO2006/079824 discloses a further improvement in which pulsed input light is used and the returning light recorded at a timing such that the majority of the light recorded is diffuse light, ie the eye is used as an integrating sphere whereby the signal to noise ratio is improved.
  • the present invention relates to a particular manner of applying the above technology to facilitate its convenient use by the subject or another person.
  • apparatus for monitoring a human or animal subject's bodily function in vivo comprising a telecommunication device provided with an eyepiece for locating a subject's eye relative to a light source and light recording means, the apparatus being arranged to direct light into the subject's eye through the pupil of the eye and to record light returning through the pupil from the interior of the eye and to transmit data recorded to remote analysing means.
  • the remote analysing means is arranged to analyse the data transmitted thereto and to transmit back to the apparatus an indication of said analysis.
  • a preferred form of the invention comprises a mobile telephone with a built-in camera and flashlight and an eyepiece for locating the subject's eye relative to a camera lens of the telephone.
  • the flash is used to direct light into the subject's eye and the camera is used to record the light returning from the retina.
  • the image or data recorded is then transmitted by the telephone to remote analysing means, eg a spectrophotometer, and the result of this analysis is transmitted back to the mobile telephone to the subject.
  • the image/data recorded may, in a preferred embodiment, be what is commonly referred to as Ved eye'.
  • the apparatus may have particular application for the monitoring of glucose levels in the blood (via the blood vessels of the retina) to enable a diabetic to determine what medication they require at that time.
  • Figure 1 is a schematic diagram illustrating use of a preferred embodiment of the invention.
  • Figure 2 is an enlarged cross-sectional view of a subject's eye located by an eyepiece of apparatus such as that illustrated in Figure 1. DESCRIPTION OF PREFERRED EMBODIMENT
  • Figure 1 shows a mobile telephone 1 with a built-in camera 2, comprising a lens 3, one or more flash lights 4, eg LEDs, and a CCD array 5 for recording the light received thereby.
  • a transparent window 6 is provided in front of the lens 3 to protect this from damage.
  • the mobile telephone is also provided with an eyepiece 7 in the form of a flexible cowl around the window 6 and LEDs 4.
  • a subject can place his or her eye 8 in front of the camera 2 with the eyepiece 7 in contact with the subject's face around the periphery of the eye 8.
  • Figure 2 shows an enlarged view of an eye 8 located by an eyepiece 7 in front of a camera lens 3.
  • the Figure shows the retina 10, lens 11, iris 12, pupil 13 and cornea 14 of the eye.
  • a bodily condition of the subject can be monitored by examination of the retina of the eye and, in particular, the blood vessels in the retina, eg by spectrophotometric analysis of light returning from the retina 10 as described in further detail in WO 90/12534.
  • the light returning from the eye is sensed by a CCD or CMOS array 5.
  • the data therefrom may then be stored in the telephone's memory and transmitted in a similar manner to the transmission of a photograph or other data by a known mobile telephone.
  • the data is received by a transceiver 20 at a remote location.
  • the transceiver comprises or is in communication with a spectrophotometer which carries out an analysis of the data received.
  • the results of this analysis are then transmitted back to the mobile telephone 1 to inform the subject of the results. This may, for example, be by a voice message or a text message.
  • the eyepiece 7 serves to exclude ambient light from entering the eye and to locate the eye 8 in line with and at the appropriate distance from the lens 3. This distance should be carefully set and the eyepiece 7 may be adjusted to suit a particular subject prior to its first use and to ensure that this distance is the same each time the apparatus is used by that subject.
  • the length of the eyepiece 7 and/or the position of the lens 3 may be adjustable to locate the eye at the desired distance from the lens 3.
  • an adjustable lens eg a fluid filled lens the focal length of which can be altered by adjusting the pressure of the fluid therein.
  • the light source 4 may be similar to a conventional flashlight in a mobile telephone, eg an LED emitting white light. In alternative arrangements, more than one LED may be provided and each may emit a different wavelength depending on the substance to be monitored.
  • an infra-red wavelength may be used.
  • alignment means may be provided to move the light source laterally with respect to the eye so it can be aligned accurately with the centre of the pupil and can following small movements of the eye.
  • the light returning from the eye that is recorded may be that which sometimes causes Ved eye' in a photograph of a person, this being light that is returning from the blood vessels in the retina.
  • a pulsed light source is used and the detection of light returning from the eye is arranged at a set timing so as to reduce the amount of light reflected from the cornea or the lens 11 that is detected thereby increasing the signal to noise ration for light returning from the interior of the eye.
  • this has the advantage of ensuring the light returning from the eye is predominantly diffuse light, which also improves the measurements made by reducing the effect of variations in the illumination of the eye. Further details of this are provided in WO2006/079824 so will not be discussed further here.
  • a pupillometer may also be provided to assist in aligning the eye with the lens. This is described in WO02/071932 so will not be described further here.
  • the mobile telephone is a conventional camera phone with a suitable eyepiece fitted thereto.
  • a specifically modified mobile telephone may be provided. This has the advantage that the lighting means, the lens, the light detector and the software controlling these can be modified or adapted to assist in providing the functions described herein.
  • a subject may, for example, be provided with a mobile phone which can be used as a telephone but which is also specifically adapted to provide the required functions, eg to sense glucose for someone with diabetes.
  • a similar instrument may also be used, for example, in a doctor's surgery or on the ward in a hospital.
  • the apparatus is to be used for more than one person, it preferably adjustable so that the length of the eyepiece and/or position of the lens 3 can be adjusted. Preferably, it can also record the identity of the subject, eg by way of iris or DNA recognition (as described in the above-mentioned prior art documents).
  • the apparatus described above thus provides, in its simplest form, a user- friendly device that can be used by a subject at home to monitor a bodily function as represented by the presence of a given substance in the blood.
  • a user- friendly device that can be used by a subject at home to monitor a bodily function as represented by the presence of a given substance in the blood.
  • a particular example is the monitoring of glucose levels in the blood for a diabetic but many other uses are possible.
  • More elaborate versions of the device may be provided for use by doctors or nurse or within a hospital.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Multimedia (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Apparatus for monitoring a human or animal subject's bodily function in vivo comprising a telecommunication device (eg a mobile phone) (1) provided with an eyepiece (7) for locating a subject's eye relative to a light source (4) and light recording means (eg a camera) (5), the apparatus being arranged to direct light into the subject's eye (8) through the pupil of the eye (8) and to record light returning through the pupil from the interior of the eye (8) and to transmit data recorded to remote analysing means (20). The apparatus may be used to monitor a substance in the subject's blood, eg the glucose levels of a diabetic.

Description

APPARATUS FOR MONITORING A HUMAN OR ANIMAL SUBJECT'S BODILY
FUNCTION
TECHNICAL FIELD
This invention relates to apparatus for monitoring a human or animal subject's bodily function in vivo via the subject's eye.
BACKGROUND ART
Apparatus for carrying out such monitoring has previously been proposed. WO90/12534 describes such a device and a wide range of uses to which this can be put and the disclosure thereof is incorporated herein.
WO02/071932 discloses an improvement to this apparatus in which a pupillometer is used to assist in aligning the apparatus with the pupil of the eye and WO2006/079824 discloses a further improvement in which pulsed input light is used and the returning light recorded at a timing such that the majority of the light recorded is diffuse light, ie the eye is used as an integrating sphere whereby the signal to noise ratio is improved. The disclosure of both these documents is also incorporated herein.
The present invention relates to a particular manner of applying the above technology to facilitate its convenient use by the subject or another person.
SUMMARY OF INVENTION
According to a first aspect of the invention, there is provided apparatus for monitoring a human or animal subject's bodily function in vivo comprising a telecommunication device provided with an eyepiece for locating a subject's eye relative to a light source and light recording means, the apparatus being arranged to direct light into the subject's eye through the pupil of the eye and to record light returning through the pupil from the interior of the eye and to transmit data recorded to remote analysing means.
Preferably the remote analysing means is arranged to analyse the data transmitted thereto and to transmit back to the apparatus an indication of said analysis.
A preferred form of the invention comprises a mobile telephone with a built-in camera and flashlight and an eyepiece for locating the subject's eye relative to a camera lens of the telephone. The flash is used to direct light into the subject's eye and the camera is used to record the light returning from the retina. The image or data recorded is then transmitted by the telephone to remote analysing means, eg a spectrophotometer, and the result of this analysis is transmitted back to the mobile telephone to the subject. The image/data recorded may, in a preferred embodiment, be what is commonly referred to as Ved eye'.
The apparatus may have particular application for the monitoring of glucose levels in the blood (via the blood vessels of the retina) to enable a diabetic to determine what medication they require at that time.
Other preferred or optional features of the invention will be apparent from the following description.
BRIEF DESCRIPTION OF DRAWINGS
The invention will now be further described, merely by way of example, with reference to the accompanying drawings, in which:
Figure 1 is a schematic diagram illustrating use of a preferred embodiment of the invention, and
Figure 2 is an enlarged cross-sectional view of a subject's eye located by an eyepiece of apparatus such as that illustrated in Figure 1. DESCRIPTION OF PREFERRED EMBODIMENT
Figure 1 shows a mobile telephone 1 with a built-in camera 2, comprising a lens 3, one or more flash lights 4, eg LEDs, and a CCD array 5 for recording the light received thereby. A transparent window 6 is provided in front of the lens 3 to protect this from damage. The mobile telephone is also provided with an eyepiece 7 in the form of a flexible cowl around the window 6 and LEDs 4. As shown, a subject can place his or her eye 8 in front of the camera 2 with the eyepiece 7 in contact with the subject's face around the periphery of the eye 8.
Figure 2 shows an enlarged view of an eye 8 located by an eyepiece 7 in front of a camera lens 3. The Figure shows the retina 10, lens 11, iris 12, pupil 13 and cornea 14 of the eye.
A bodily condition of the subject can be monitored by examination of the retina of the eye and, in particular, the blood vessels in the retina, eg by spectrophotometric analysis of light returning from the retina 10 as described in further detail in WO 90/12534. In the apparatus described herein, the light returning from the eye is sensed by a CCD or CMOS array 5. The data therefrom may then be stored in the telephone's memory and transmitted in a similar manner to the transmission of a photograph or other data by a known mobile telephone. The data is received by a transceiver 20 at a remote location. The transceiver comprises or is in communication with a spectrophotometer which carries out an analysis of the data received. The results of this analysis are then transmitted back to the mobile telephone 1 to inform the subject of the results. This may, for example, be by a voice message or a text message.
The eyepiece 7 serves to exclude ambient light from entering the eye and to locate the eye 8 in line with and at the appropriate distance from the lens 3. This distance should be carefully set and the eyepiece 7 may be adjusted to suit a particular subject prior to its first use and to ensure that this distance is the same each time the apparatus is used by that subject. In a preferred embodiment, the length of the eyepiece 7 and/or the position of the lens 3 may be adjustable to locate the eye at the desired distance from the lens 3. Another possibility would be to use an adjustable lens, eg a fluid filled lens the focal length of which can be altered by adjusting the pressure of the fluid therein.
The light source 4 may be similar to a conventional flashlight in a mobile telephone, eg an LED emitting white light. In alternative arrangements, more than one LED may be provided and each may emit a different wavelength depending on the substance to be monitored.
In some cases, an infra-red wavelength may be used. In some cases, it maybe desirable to focus the illumination light in the plane of the pupil 13 (so as to provide a Maxwellian view) in which case the illumination light may be provided via an optical fibre and/or a focussing lens as described in the prior art documents referred to above. In addition, alignment means may be provided to move the light source laterally with respect to the eye so it can be aligned accurately with the centre of the pupil and can following small movements of the eye.
The light returning from the eye that is recorded may be that which sometimes causes Ved eye' in a photograph of a person, this being light that is returning from the blood vessels in the retina.
In a preferred arrangement, a pulsed light source is used and the detection of light returning from the eye is arranged at a set timing so as to reduce the amount of light reflected from the cornea or the lens 11 that is detected thereby increasing the signal to noise ration for light returning from the interior of the eye. In addition, this has the advantage of ensuring the light returning from the eye is predominantly diffuse light, which also improves the measurements made by reducing the effect of variations in the illumination of the eye. Further details of this are provided in WO2006/079824 so will not be discussed further here. In preferred embodiments, a pupillometer may also be provided to assist in aligning the eye with the lens. This is described in WO02/071932 so will not be described further here.
As indicated above, in a preferred embodiment, the mobile telephone is a conventional camera phone with a suitable eyepiece fitted thereto. In another embodiment, a specifically modified mobile telephone may be provided. This has the advantage that the lighting means, the lens, the light detector and the software controlling these can be modified or adapted to assist in providing the functions described herein. A subject may, for example, be provided with a mobile phone which can be used as a telephone but which is also specifically adapted to provide the required functions, eg to sense glucose for someone with diabetes. A similar instrument may also be used, for example, in a doctor's surgery or on the ward in a hospital.
If the apparatus is to be used for more than one person, it preferably adjustable so that the length of the eyepiece and/or position of the lens 3 can be adjusted. Preferably, it can also record the identity of the subject, eg by way of iris or DNA recognition (as described in the above-mentioned prior art documents).
The apparatus described above thus provides, in its simplest form, a user- friendly device that can be used by a subject at home to monitor a bodily function as represented by the presence of a given substance in the blood. A particular example is the monitoring of glucose levels in the blood for a diabetic but many other uses are possible. More elaborate versions of the device may be provided for use by doctors or nurse or within a hospital.

Claims

1. Apparatus for monitoring a human or animal subject's bodily function in vivo comprising a telecommunication device provided with an eyepiece for locating a subject's eye relative to a light source and light recording means, the apparatus being arranged to direct light into the subject's eye through the pupil of the eye and to record light returning through the pupil from the interior of the eye and to transmit data recorded to remote analysing means.
2. Apparatus as claimed in claim 1 in which the remote analysing means is arranged to analyse the data transmitted thereto and to transmit back to the apparatus an indication of said analysis.
3. Apparatus as claimed in claim 1 or 2 which comprises a mobile telephone with a built-in camera and flashlight and an eyepiece for locating the subject's eye relative to a camera lens of the telephone.
4. Apparatus as claimed in claim 3 in which the flash is arranged to direct light into the subject's eye and the camera is arranged to record the light returning from the retina.
5. Apparatus as claimed in claim 4 in which an image or data recorded by the camera is arranged to be transmitted by the telephone to remote analysing means (eg a spectrophotometer) and the result of this analysis transmitted back to the mobile telephone.
6. Apparatus as claimed in any preceding claim in which the image/data recorded is that known as 'red eye'.
7. Apparatus as claimed in any preceding claim arranged for the monitoring of glucose levels in the blood (via the blood vessels of the retina) to enable a diabetic to determine what medication they require at that time.
8. Apparatus as claimed in any preceding claim in which the eyepiece comprises a flexible cowl for placing in contact with a subject's face around the periphery of the eye.
9. Apparatus as claimed in any preceding claim in which the eyepiece comprises a lens and the eyepiece may be adjusted to set the distance between the lens and the subject's eye.
10. Apparatus as claimed in any of claim 1 to 8 in which the eyepiece comprises an adjustable lens (eg a fluid filled lens).
11. Apparatus as claimed in any preceding claim in which the light source comprises one or more LEDs, preferably emitting different wavelengths.
12. Apparatus as claimed in claim 11 in which at least one or more of the LEDs emits an infra-red wavelength.
13. Apparatus as claimed in any preceding claim in which the light source is arranged such that the illumination light therefrom can be focussed in the plane of the pupil of the subject's eye.
14. Apparatus as claimed in any preceding claim in which alignment means are provided for moving the light source laterally with respect to the subject's eye.
15. Apparatus as claimed in any preceding claim in which the light source is arranged to provide pulsed illumination light.
16. Apparatus as claimed in claim 15 in which the light recording means is arranged to detect light at a set timing relative to the pulsed illumination so as to reduce the amount of light reflected from the cornea of the subject's eye that is detected thereby increasing the signal to noise ratio.
17. Apparatus as claimed in any preceding claim comprising a pupillometer to assist in alignment with the subject's eye.
18. Apparatus as claimed in any preceding claim arranged to record the identity of the subject (eg by way of iris or DNA recognition).
PCT/GB2008/001144 2008-03-31 2008-03-31 Apparatus for monitoring a human or animal subject's bodily function WO2009122114A1 (en)

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Cited By (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011089427A1 (en) * 2010-01-21 2011-07-28 Christopher Glynn Non-invasive spectrophotometer and related method
US9058653B1 (en) 2011-06-10 2015-06-16 Flir Systems, Inc. Alignment of visible light sources based on thermal images
US9143703B2 (en) 2011-06-10 2015-09-22 Flir Systems, Inc. Infrared camera calibration techniques
US9208542B2 (en) 2009-03-02 2015-12-08 Flir Systems, Inc. Pixel-wise noise reduction in thermal images
US9207708B2 (en) 2010-04-23 2015-12-08 Flir Systems, Inc. Abnormal clock rate detection in imaging sensor arrays
US9235023B2 (en) 2011-06-10 2016-01-12 Flir Systems, Inc. Variable lens sleeve spacer
US9235876B2 (en) 2009-03-02 2016-01-12 Flir Systems, Inc. Row and column noise reduction in thermal images
US9292909B2 (en) 2009-06-03 2016-03-22 Flir Systems, Inc. Selective image correction for infrared imaging devices
USD765081S1 (en) 2012-05-25 2016-08-30 Flir Systems, Inc. Mobile communications device attachment with camera
US9451183B2 (en) 2009-03-02 2016-09-20 Flir Systems, Inc. Time spaced infrared image enhancement
US9473681B2 (en) 2011-06-10 2016-10-18 Flir Systems, Inc. Infrared camera system housing with metalized surface
US9509924B2 (en) 2011-06-10 2016-11-29 Flir Systems, Inc. Wearable apparatus with integrated infrared imaging module
US9521289B2 (en) 2011-06-10 2016-12-13 Flir Systems, Inc. Line based image processing and flexible memory system
US9517679B2 (en) 2009-03-02 2016-12-13 Flir Systems, Inc. Systems and methods for monitoring vehicle occupants
US9635220B2 (en) 2012-07-16 2017-04-25 Flir Systems, Inc. Methods and systems for suppressing noise in images
US9635285B2 (en) 2009-03-02 2017-04-25 Flir Systems, Inc. Infrared imaging enhancement with fusion
US9674458B2 (en) 2009-06-03 2017-06-06 Flir Systems, Inc. Smart surveillance camera systems and methods
US9706138B2 (en) 2010-04-23 2017-07-11 Flir Systems, Inc. Hybrid infrared sensor array having heterogeneous infrared sensors
US9706137B2 (en) 2011-06-10 2017-07-11 Flir Systems, Inc. Electrical cabinet infrared monitor
US9706139B2 (en) 2011-06-10 2017-07-11 Flir Systems, Inc. Low power and small form factor infrared imaging
US9716843B2 (en) 2009-06-03 2017-07-25 Flir Systems, Inc. Measurement device for electrical installations and related methods
US9723227B2 (en) 2011-06-10 2017-08-01 Flir Systems, Inc. Non-uniformity correction techniques for infrared imaging devices
US9756264B2 (en) 2009-03-02 2017-09-05 Flir Systems, Inc. Anomalous pixel detection
US9756262B2 (en) 2009-06-03 2017-09-05 Flir Systems, Inc. Systems and methods for monitoring power systems
US9807319B2 (en) 2009-06-03 2017-10-31 Flir Systems, Inc. Wearable imaging devices, systems, and methods
US9811884B2 (en) 2012-07-16 2017-11-07 Flir Systems, Inc. Methods and systems for suppressing atmospheric turbulence in images
US9819880B2 (en) 2009-06-03 2017-11-14 Flir Systems, Inc. Systems and methods of suppressing sky regions in images
US9843742B2 (en) 2009-03-02 2017-12-12 Flir Systems, Inc. Thermal image frame capture using de-aligned sensor array
US9848134B2 (en) 2010-04-23 2017-12-19 Flir Systems, Inc. Infrared imager with integrated metal layers
US9900526B2 (en) 2011-06-10 2018-02-20 Flir Systems, Inc. Techniques to compensate for calibration drifts in infrared imaging devices
US9918023B2 (en) 2010-04-23 2018-03-13 Flir Systems, Inc. Segmented focal plane array architecture
US9948872B2 (en) 2009-03-02 2018-04-17 Flir Systems, Inc. Monitor and control systems and methods for occupant safety and energy efficiency of structures
US9961277B2 (en) 2011-06-10 2018-05-01 Flir Systems, Inc. Infrared focal plane array heat spreaders
US9973692B2 (en) 2013-10-03 2018-05-15 Flir Systems, Inc. Situational awareness by compressed display of panoramic views
US9986175B2 (en) 2009-03-02 2018-05-29 Flir Systems, Inc. Device attachment with infrared imaging sensor
US9998697B2 (en) 2009-03-02 2018-06-12 Flir Systems, Inc. Systems and methods for monitoring vehicle occupants
US10051210B2 (en) 2011-06-10 2018-08-14 Flir Systems, Inc. Infrared detector array with selectable pixel binning systems and methods
US10079982B2 (en) 2011-06-10 2018-09-18 Flir Systems, Inc. Determination of an absolute radiometric value using blocked infrared sensors
US10091439B2 (en) 2009-06-03 2018-10-02 Flir Systems, Inc. Imager with array of multiple infrared imaging modules
US10169666B2 (en) 2011-06-10 2019-01-01 Flir Systems, Inc. Image-assisted remote control vehicle systems and methods
US10244190B2 (en) 2009-03-02 2019-03-26 Flir Systems, Inc. Compact multi-spectrum imaging with fusion
US10389953B2 (en) 2011-06-10 2019-08-20 Flir Systems, Inc. Infrared imaging device having a shutter
US10757308B2 (en) 2009-03-02 2020-08-25 Flir Systems, Inc. Techniques for device attachment with dual band imaging sensor
US10841508B2 (en) 2011-06-10 2020-11-17 Flir Systems, Inc. Electrical cabinet infrared monitor systems and methods
US11297264B2 (en) 2014-01-05 2022-04-05 Teledyne Fur, Llc Device attachment with dual band imaging sensor

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012534A1 (en) 1989-04-26 1990-11-01 Glynn Christopher J Device for monitoring body functions
EP0776628A2 (en) * 1995-10-31 1997-06-04 Akitoshi Yoshida Intraocular substance measuring apparatus
US6312393B1 (en) * 1996-09-04 2001-11-06 Marcio Marc A. M. Abreu Contact device for placement in direct apposition to the conjunctive of the eye
WO2002071932A1 (en) 2001-03-09 2002-09-19 Christopher Glynn Non-invasive spectrophotometer
US20030050544A1 (en) * 2001-09-13 2003-03-13 Wilson Routt Non-invasive measurement of blood analytes using photodynamics
WO2004017825A1 (en) * 2002-08-26 2004-03-04 Kabushiki Kaisha Topcon Portable ophthalmic apparatus and ophthalmic system
US20050264758A1 (en) * 2003-10-01 2005-12-01 Masahiro Wakamori Eye image imaging device
WO2006079824A1 (en) 2005-01-27 2006-08-03 H-Icheck Ltd Improved device for monitoring body functions
WO2007069294A1 (en) * 2005-12-12 2007-06-21 Atsuhiro Ueda Data sampling device for image diagnosis and imaging adapter for use in that device

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012534A1 (en) 1989-04-26 1990-11-01 Glynn Christopher J Device for monitoring body functions
EP0776628A2 (en) * 1995-10-31 1997-06-04 Akitoshi Yoshida Intraocular substance measuring apparatus
US6312393B1 (en) * 1996-09-04 2001-11-06 Marcio Marc A. M. Abreu Contact device for placement in direct apposition to the conjunctive of the eye
WO2002071932A1 (en) 2001-03-09 2002-09-19 Christopher Glynn Non-invasive spectrophotometer
US20030050544A1 (en) * 2001-09-13 2003-03-13 Wilson Routt Non-invasive measurement of blood analytes using photodynamics
WO2004017825A1 (en) * 2002-08-26 2004-03-04 Kabushiki Kaisha Topcon Portable ophthalmic apparatus and ophthalmic system
US20050264758A1 (en) * 2003-10-01 2005-12-01 Masahiro Wakamori Eye image imaging device
WO2006079824A1 (en) 2005-01-27 2006-08-03 H-Icheck Ltd Improved device for monitoring body functions
WO2007069294A1 (en) * 2005-12-12 2007-06-21 Atsuhiro Ueda Data sampling device for image diagnosis and imaging adapter for use in that device

Cited By (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9517679B2 (en) 2009-03-02 2016-12-13 Flir Systems, Inc. Systems and methods for monitoring vehicle occupants
US10757308B2 (en) 2009-03-02 2020-08-25 Flir Systems, Inc. Techniques for device attachment with dual band imaging sensor
US10244190B2 (en) 2009-03-02 2019-03-26 Flir Systems, Inc. Compact multi-spectrum imaging with fusion
US9208542B2 (en) 2009-03-02 2015-12-08 Flir Systems, Inc. Pixel-wise noise reduction in thermal images
US10033944B2 (en) 2009-03-02 2018-07-24 Flir Systems, Inc. Time spaced infrared image enhancement
US9998697B2 (en) 2009-03-02 2018-06-12 Flir Systems, Inc. Systems and methods for monitoring vehicle occupants
US9235876B2 (en) 2009-03-02 2016-01-12 Flir Systems, Inc. Row and column noise reduction in thermal images
US9986175B2 (en) 2009-03-02 2018-05-29 Flir Systems, Inc. Device attachment with infrared imaging sensor
US9948872B2 (en) 2009-03-02 2018-04-17 Flir Systems, Inc. Monitor and control systems and methods for occupant safety and energy efficiency of structures
US9451183B2 (en) 2009-03-02 2016-09-20 Flir Systems, Inc. Time spaced infrared image enhancement
US9843742B2 (en) 2009-03-02 2017-12-12 Flir Systems, Inc. Thermal image frame capture using de-aligned sensor array
US9756264B2 (en) 2009-03-02 2017-09-05 Flir Systems, Inc. Anomalous pixel detection
US9635285B2 (en) 2009-03-02 2017-04-25 Flir Systems, Inc. Infrared imaging enhancement with fusion
US9756262B2 (en) 2009-06-03 2017-09-05 Flir Systems, Inc. Systems and methods for monitoring power systems
US9292909B2 (en) 2009-06-03 2016-03-22 Flir Systems, Inc. Selective image correction for infrared imaging devices
US9819880B2 (en) 2009-06-03 2017-11-14 Flir Systems, Inc. Systems and methods of suppressing sky regions in images
US10091439B2 (en) 2009-06-03 2018-10-02 Flir Systems, Inc. Imager with array of multiple infrared imaging modules
US9674458B2 (en) 2009-06-03 2017-06-06 Flir Systems, Inc. Smart surveillance camera systems and methods
US9843743B2 (en) 2009-06-03 2017-12-12 Flir Systems, Inc. Infant monitoring systems and methods using thermal imaging
US9716843B2 (en) 2009-06-03 2017-07-25 Flir Systems, Inc. Measurement device for electrical installations and related methods
US9807319B2 (en) 2009-06-03 2017-10-31 Flir Systems, Inc. Wearable imaging devices, systems, and methods
US10117570B2 (en) 2010-01-21 2018-11-06 Murwillumbah Manufacturing Limited Non-invasive spectrophotometer and related method
WO2011089427A1 (en) * 2010-01-21 2011-07-28 Christopher Glynn Non-invasive spectrophotometer and related method
US9918023B2 (en) 2010-04-23 2018-03-13 Flir Systems, Inc. Segmented focal plane array architecture
US9207708B2 (en) 2010-04-23 2015-12-08 Flir Systems, Inc. Abnormal clock rate detection in imaging sensor arrays
US9848134B2 (en) 2010-04-23 2017-12-19 Flir Systems, Inc. Infrared imager with integrated metal layers
US9706138B2 (en) 2010-04-23 2017-07-11 Flir Systems, Inc. Hybrid infrared sensor array having heterogeneous infrared sensors
US9723227B2 (en) 2011-06-10 2017-08-01 Flir Systems, Inc. Non-uniformity correction techniques for infrared imaging devices
US9706137B2 (en) 2011-06-10 2017-07-11 Flir Systems, Inc. Electrical cabinet infrared monitor
US9509924B2 (en) 2011-06-10 2016-11-29 Flir Systems, Inc. Wearable apparatus with integrated infrared imaging module
US9473681B2 (en) 2011-06-10 2016-10-18 Flir Systems, Inc. Infrared camera system housing with metalized surface
US9723228B2 (en) 2011-06-10 2017-08-01 Flir Systems, Inc. Infrared camera system architectures
US9538038B2 (en) 2011-06-10 2017-01-03 Flir Systems, Inc. Flexible memory systems and methods
US9900526B2 (en) 2011-06-10 2018-02-20 Flir Systems, Inc. Techniques to compensate for calibration drifts in infrared imaging devices
US9716844B2 (en) 2011-06-10 2017-07-25 Flir Systems, Inc. Low power and small form factor infrared imaging
US10841508B2 (en) 2011-06-10 2020-11-17 Flir Systems, Inc. Electrical cabinet infrared monitor systems and methods
US9961277B2 (en) 2011-06-10 2018-05-01 Flir Systems, Inc. Infrared focal plane array heat spreaders
US9058653B1 (en) 2011-06-10 2015-06-16 Flir Systems, Inc. Alignment of visible light sources based on thermal images
US9706139B2 (en) 2011-06-10 2017-07-11 Flir Systems, Inc. Low power and small form factor infrared imaging
US9235023B2 (en) 2011-06-10 2016-01-12 Flir Systems, Inc. Variable lens sleeve spacer
US10389953B2 (en) 2011-06-10 2019-08-20 Flir Systems, Inc. Infrared imaging device having a shutter
US10051210B2 (en) 2011-06-10 2018-08-14 Flir Systems, Inc. Infrared detector array with selectable pixel binning systems and methods
US10079982B2 (en) 2011-06-10 2018-09-18 Flir Systems, Inc. Determination of an absolute radiometric value using blocked infrared sensors
US9521289B2 (en) 2011-06-10 2016-12-13 Flir Systems, Inc. Line based image processing and flexible memory system
US10250822B2 (en) 2011-06-10 2019-04-02 Flir Systems, Inc. Wearable apparatus with integrated infrared imaging module
US10169666B2 (en) 2011-06-10 2019-01-01 Flir Systems, Inc. Image-assisted remote control vehicle systems and methods
US10230910B2 (en) 2011-06-10 2019-03-12 Flir Systems, Inc. Infrared camera system architectures
US9143703B2 (en) 2011-06-10 2015-09-22 Flir Systems, Inc. Infrared camera calibration techniques
USD765081S1 (en) 2012-05-25 2016-08-30 Flir Systems, Inc. Mobile communications device attachment with camera
US9635220B2 (en) 2012-07-16 2017-04-25 Flir Systems, Inc. Methods and systems for suppressing noise in images
US9811884B2 (en) 2012-07-16 2017-11-07 Flir Systems, Inc. Methods and systems for suppressing atmospheric turbulence in images
US9973692B2 (en) 2013-10-03 2018-05-15 Flir Systems, Inc. Situational awareness by compressed display of panoramic views
US11297264B2 (en) 2014-01-05 2022-04-05 Teledyne Fur, Llc Device attachment with dual band imaging sensor

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