WO2009120802A3 - Methods and compositions for identifying biomarkers useful in characterizing biological states - Google Patents

Methods and compositions for identifying biomarkers useful in characterizing biological states Download PDF

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Publication number
WO2009120802A3
WO2009120802A3 PCT/US2009/038288 US2009038288W WO2009120802A3 WO 2009120802 A3 WO2009120802 A3 WO 2009120802A3 US 2009038288 W US2009038288 W US 2009038288W WO 2009120802 A3 WO2009120802 A3 WO 2009120802A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
compositions
biological states
biomarkers useful
relates
Prior art date
Application number
PCT/US2009/038288
Other languages
French (fr)
Other versions
WO2009120802A2 (en
Inventor
James C. Willey
Erin L. Crawford
Thomas M. Blomquist
Original Assignee
The University Of Toledo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of Toledo filed Critical The University Of Toledo
Publication of WO2009120802A2 publication Critical patent/WO2009120802A2/en
Publication of WO2009120802A3 publication Critical patent/WO2009120802A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection

Abstract

The present invention relates to methods, compositions, and kits for identifying biomarkers useful in characterizing biological states. In particular, the invention relates to methods and compositions for molecular characterization of biological states by gene expression profiling. The invention also relates to assessing effects of DNA polymorphisms on regulation of transcription. The biomarkers and polymorphisms identified find use in diagnostic and treatment approaches, e.g., some embodiments of the invention provide methods and kits for detecting bronchogenic carcinoma and risks thereof.
PCT/US2009/038288 2008-03-25 2009-03-25 Methods and compositions for identifying biomarkers useful in characterizing biological states WO2009120802A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3941008P 2008-03-25 2008-03-25
US61/039,410 2008-03-25

Publications (2)

Publication Number Publication Date
WO2009120802A2 WO2009120802A2 (en) 2009-10-01
WO2009120802A3 true WO2009120802A3 (en) 2010-04-15

Family

ID=41114685

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/038288 WO2009120802A2 (en) 2008-03-25 2009-03-25 Methods and compositions for identifying biomarkers useful in characterizing biological states

Country Status (1)

Country Link
WO (1) WO2009120802A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009039190A1 (en) 2007-09-17 2009-03-26 Gene Express, Inc. Cancer risk biomarker

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639606A (en) * 1993-04-06 1997-06-17 The University Of Rochester Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
WO2004001371A2 (en) * 2001-11-02 2003-12-31 Hybrizyme Corporation Receptor capture assay
WO2005086679A2 (en) * 2004-03-05 2005-09-22 Medical College Of Ohio Methods and compositions for assessing nucleic acids and alleles
WO2006079048A2 (en) * 2005-01-21 2006-07-27 Gene Express, Inc. Databases for assessing nucleic acids

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639606A (en) * 1993-04-06 1997-06-17 The University Of Rochester Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
WO2004001371A2 (en) * 2001-11-02 2003-12-31 Hybrizyme Corporation Receptor capture assay
WO2005086679A2 (en) * 2004-03-05 2005-09-22 Medical College Of Ohio Methods and compositions for assessing nucleic acids and alleles
WO2006079048A2 (en) * 2005-01-21 2006-07-27 Gene Express, Inc. Databases for assessing nucleic acids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MIURA, A. ET AL., BMC GENOMICS *
SIMI, L. ET AL., CLINICA CHIMICA ACTA, vol. 384, 2007, pages 149 - 154 *

Also Published As

Publication number Publication date
WO2009120802A2 (en) 2009-10-01

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