WO2009118771A3 - Use of lactoferrin for prevention of neonatal sepses in premature newborns - Google Patents

Use of lactoferrin for prevention of neonatal sepses in premature newborns Download PDF

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Publication number
WO2009118771A3
WO2009118771A3 PCT/IT2009/000115 IT2009000115W WO2009118771A3 WO 2009118771 A3 WO2009118771 A3 WO 2009118771A3 IT 2009000115 W IT2009000115 W IT 2009000115W WO 2009118771 A3 WO2009118771 A3 WO 2009118771A3
Authority
WO
WIPO (PCT)
Prior art keywords
sepses
lactoferrin
neonatal
prevention
premature newborns
Prior art date
Application number
PCT/IT2009/000115
Other languages
French (fr)
Other versions
WO2009118771A2 (en
Inventor
Paolo Manzoni
Maurizio Acri
Original Assignee
Paolo Manzoni
Maurizio Acri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paolo Manzoni, Maurizio Acri filed Critical Paolo Manzoni
Publication of WO2009118771A2 publication Critical patent/WO2009118771A2/en
Publication of WO2009118771A3 publication Critical patent/WO2009118771A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis

Abstract

An optimal prophylaxis of neonatal sepses/inf ections in preterm newborns in order to prevent the infective episode, rather than curing it, envisages the use of lactoferrin as nutritional supplement irrespective of the type of alimentation adopted. Also indicated are the daily doses, to be administered via oral route according to the body weight of the premature neonate.
PCT/IT2009/000115 2008-03-26 2009-03-25 Use of lactoferrin for prevention of neonatal sepses in premature newborns WO2009118771A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM2008000163 2008-03-26
ITRM20080163 ITRM20080163A1 (en) 2008-03-26 2008-03-26 USE OF LATTOFERRINA FOR THE PREVENTION OF NEONATAL SEPSIS IN PREMATURED NEWBORNS

Publications (2)

Publication Number Publication Date
WO2009118771A2 WO2009118771A2 (en) 2009-10-01
WO2009118771A3 true WO2009118771A3 (en) 2009-11-26

Family

ID=40293205

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2009/000115 WO2009118771A2 (en) 2008-03-26 2009-03-25 Use of lactoferrin for prevention of neonatal sepses in premature newborns

Country Status (2)

Country Link
IT (1) ITRM20080163A1 (en)
WO (1) WO2009118771A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY173944A (en) * 2009-10-29 2020-02-28 Nestec Sa Nutritional compositions comprising lactoferrin and probiotics and kits of parts thereof
US8648036B2 (en) 2010-12-29 2014-02-11 Mead Johnson Nutrition Company Use of nutritional compositions including lactoferrin and one or more prebiotics in inhibiting adhesion of pathogens in the gastrointestinal tract
CN103327828B (en) * 2010-12-29 2016-05-11 Mjn美国控股有限责任公司 Use the method for nutritional composition in inhibiting pathogen
US8968722B2 (en) 2010-12-29 2015-03-03 Mead Johnson Nutrition Company Milk-based nutritional compositions containing lactoferrin and uses thereof
PE20141826A1 (en) * 2010-12-29 2014-12-17 Mjn Us Holdings Llc USE OF NUTRITIONAL COMPOSITIONS INCLUDING LACTOPHERRIN IN SUPPORT OF RESISTANCE TO DISEASES AND CONDITIONS
NZ613887A (en) * 2011-07-29 2015-09-25 Morinaga Milk Industry Co Ltd Antimicrobial activity enhancing agent
WO2023178060A1 (en) * 2022-03-14 2023-09-21 The Children's Mercy Hospital Prophylaxis of neonatal escherichia coli sepsis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991013629A1 (en) * 1990-03-14 1991-09-19 Dietrich Nitsche Use of lactoferrin to counter the toxic effects of endotoxins
WO1999052545A1 (en) * 1998-04-13 1999-10-21 New England Medical Center Hospitals, Inc. Methods and compositions for inactivating infectious agents using lactoferrin and related molecules
US6455687B1 (en) * 1990-03-08 2002-09-24 Ferradynamics, Inc Human lactoferrin
WO2004052281A2 (en) * 2002-12-06 2004-06-24 Agennix Incorporated Oral lactoferrin in the treatment of sepsis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455687B1 (en) * 1990-03-08 2002-09-24 Ferradynamics, Inc Human lactoferrin
WO1991013629A1 (en) * 1990-03-14 1991-09-19 Dietrich Nitsche Use of lactoferrin to counter the toxic effects of endotoxins
WO1999052545A1 (en) * 1998-04-13 1999-10-21 New England Medical Center Hospitals, Inc. Methods and compositions for inactivating infectious agents using lactoferrin and related molecules
WO2004052281A2 (en) * 2002-12-06 2004-06-24 Agennix Incorporated Oral lactoferrin in the treatment of sepsis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MICHAEL P SHERMAN ET AL: "Neonatal small bowel epithelia: enhancing anti-bacterial defense with lactoferrin and Lactobacillus GG", BIOMETALS, KLUWER ACADEMIC PUBLISHERS, BO, vol. 17, no. 3, 1 June 2004 (2004-06-01), pages 285 - 289, XP019232209, ISSN: 1572-8773 *

Also Published As

Publication number Publication date
ITRM20080163A1 (en) 2009-09-27
WO2009118771A2 (en) 2009-10-01

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