WO2009117640A3 - Antibodies against interleukin-10 like cytokines and uses therefor - Google Patents

Antibodies against interleukin-10 like cytokines and uses therefor Download PDF

Info

Publication number
WO2009117640A3
WO2009117640A3 PCT/US2009/037773 US2009037773W WO2009117640A3 WO 2009117640 A3 WO2009117640 A3 WO 2009117640A3 US 2009037773 W US2009037773 W US 2009037773W WO 2009117640 A3 WO2009117640 A3 WO 2009117640A3
Authority
WO
WIPO (PCT)
Prior art keywords
cytokines
binding fragments
antibodies against
uses therefor
against interleukin
Prior art date
Application number
PCT/US2009/037773
Other languages
French (fr)
Other versions
WO2009117640A2 (en
Inventor
Lynette A. Fouser
Jing Li
Paul W. Wu
Sreekumar R. Kodangattli
Original Assignee
Wyeth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth filed Critical Wyeth
Priority to CA2718634A priority Critical patent/CA2718634A1/en
Publication of WO2009117640A2 publication Critical patent/WO2009117640A2/en
Publication of WO2009117640A3 publication Critical patent/WO2009117640A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Specific binding fragments, antibodies, and antigen-binding fragments thereof that bind IL-10-like cytokines, including human interleukin-22 (IL-22) are provided. Methods of making and using such binding fragments, antibodies, and antigen-binding fragments are also provided. Kits containing such binding fragments, antibodies, and antigen-binding fragments are also provided.
PCT/US2009/037773 2008-03-21 2009-03-20 Antibodies against interleukin-10 like cytokines and uses therefor WO2009117640A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2718634A CA2718634A1 (en) 2008-03-21 2009-03-20 Antibodies against interleukin-10-like cytokines and uses therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6471808P 2008-03-21 2008-03-21
US61/064,718 2008-03-21

Publications (2)

Publication Number Publication Date
WO2009117640A2 WO2009117640A2 (en) 2009-09-24
WO2009117640A3 true WO2009117640A3 (en) 2009-12-10

Family

ID=40852583

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/037773 WO2009117640A2 (en) 2008-03-21 2009-03-20 Antibodies against interleukin-10 like cytokines and uses therefor

Country Status (2)

Country Link
CA (1) CA2718634A1 (en)
WO (1) WO2009117640A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103182072B (en) * 2011-12-27 2017-05-03 健能隆医药技术（上海）有限公司 Application of interleukin-22 in treating and preventing nerve injuries and neurodegeneration diseases
KR102426481B1 (en) 2013-03-15 2022-07-27 제넨테크, 인크. Il-22 polypeptides and il-22 fc fusion proteins and methods of use
CN109425450B (en) * 2017-08-23 2021-04-23 北京纳米能源与系统研究所 Sensor and electronic, bionic skin and bionic communication equipment applying same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003023012A2 (en) * 2001-09-10 2003-03-20 Ludwig Institute For Cancer Research Crystal structure of interleukin-22 and uses thereof
WO2005000897A2 (en) * 2003-06-23 2005-01-06 Genetics Institute, Llc Antibodies against interleukin-22 and uses therefor
WO2007100643A2 (en) * 2006-02-21 2007-09-07 Wyeth Methods of using antibodies against human il-22

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003023012A2 (en) * 2001-09-10 2003-03-20 Ludwig Institute For Cancer Research Crystal structure of interleukin-22 and uses thereof
WO2005000897A2 (en) * 2003-06-23 2005-01-06 Genetics Institute, Llc Antibodies against interleukin-22 and uses therefor
WO2007100643A2 (en) * 2006-02-21 2007-09-07 Wyeth Methods of using antibodies against human il-22

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
KOTENKO SERGEI V: "The family of IL-10-related cytokines and their receptors: Related, but to what extent?", CYTOKINE AND GROWTH FACTOR REVIEWS, OXFORD, GB, vol. 13, no. 3, 1 June 2002 (2002-06-01), pages 223 - 240, XP002307631, ISSN: 1359-6101 *
LOGSDON N J ET AL: "The IL-10R2 Binding Hot Spot on IL-22 is Located on the N-terminal Helix and is Dependent on N-linked Glycosylation", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 342, no. 2, 10 September 2004 (2004-09-10), pages 503 - 514, XP004725921, ISSN: 0022-2836 *
NAGEM RONALDO ALVES PINTO ET AL: "Crystal structure of recombinant human interleukin-22", STRUCTURE (CAMBRIDGE), vol. 10, no. 8, August 2002 (2002-08-01), pages 1051 - 1062, XP002538405, ISSN: 0969-2126 *
WU PAUL W ET AL: "IL-22R, IL-10R2, and IL-22BP Binding Sites Are Topologically Juxtaposed on Adjacent and Overlapping Surfaces of IL-22", JOURNAL OF MOLECULAR BIOLOGY, vol. 382, no. 5, October 2008 (2008-10-01), pages 1168 - 1183, XP002538406, ISSN: 0022-2836 *

Also Published As

Publication number Publication date
WO2009117640A2 (en) 2009-09-24
CA2718634A1 (en) 2009-09-24

Similar Documents

Publication Publication Date Title
AU2009260320A8 (en) Antibodies to IL-6 and their uses
IL258718A (en) Human anti-il-23 antibodies,compositions, methods and uses
EP4025602A4 (en) Antibodies binding tslp and uses thereof
WO2009136286A3 (en) Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
WO2007116360A3 (en) Antibodies that bind human protein tyrosine phosphatase beta (hptpbeta) and uses thereof
WO2009052400A8 (en) Antibodies that bind to mammalian ngal and uses thereof
WO2008140493A3 (en) Anti-egfr family antibodies, bispecific anti-egfr family antibodies and methods of use thereof
WO2008150485A3 (en) Erbb2 binding proteins and use thereof
WO2011053763A3 (en) Il-17a antagonists
WO2009040134A8 (en) Heparin-binding epidermal growth factor-like growth factor antigen binding proteins
HK1116398A1 (en) Anti-il-6 antibodies, compositions, methods and uses il-6
WO2012047583A3 (en) Antibodies binding human collagen ii
WO2008060705A8 (en) Anti-dll4 antibodies and methods using same
WO2010136311A3 (en) Compositions and methods for antibodies targeting complement protein c3b
WO2008106134A3 (en) Engineered anti-il-23r antibodies
PT2327423T (en) Human antibodies against human interleukin-22 (il-22)
WO2010128407A3 (en) Anti-il-17f antibodies and methods of use thereof
WO2009052125A9 (en) Human anti-amyloid antibodies, compositions, methods and uses
WO2010136483A3 (en) Antigen-binding proteins
WO2009055074A3 (en) Erbb2 binding proteins and use thereof
WO2008088823A3 (en) Methods for treating psoriasis
WO2007106915A3 (en) Antibodies to egfl7 and methods for their use
EP3848391A4 (en) Antibodies binding to human il-4r, preparation method therefor and use thereof
EP2281004A4 (en) Prostate specific membrane antigen antibodies and antigen binding fragments
WO2009117640A3 (en) Antibodies against interleukin-10 like cytokines and uses therefor

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09722720

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2718634

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2011500973

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: JP

122 Ep: pct application non-entry in european phase

Ref document number: 09722720

Country of ref document: EP

Kind code of ref document: A2