WO2009116774A3 - 혈관 재협착 치료 또는 예방용 조성물 - Google Patents

혈관 재협착 치료 또는 예방용 조성물 Download PDF

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Publication number
WO2009116774A3
WO2009116774A3 PCT/KR2009/001316 KR2009001316W WO2009116774A3 WO 2009116774 A3 WO2009116774 A3 WO 2009116774A3 KR 2009001316 W KR2009001316 W KR 2009001316W WO 2009116774 A3 WO2009116774 A3 WO 2009116774A3
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WO
WIPO (PCT)
Prior art keywords
composition
prevention
treatment
restenosis
formula
Prior art date
Application number
PCT/KR2009/001316
Other languages
English (en)
French (fr)
Other versions
WO2009116774A2 (ko
Inventor
배윤수
이기인
강상원
이지현
Original Assignee
이화여자대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이화여자대학교 산학협력단 filed Critical 이화여자대학교 산학협력단
Publication of WO2009116774A2 publication Critical patent/WO2009116774A2/ko
Publication of WO2009116774A3 publication Critical patent/WO2009116774A3/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Abstract

본 발명은 화학식 1 또는 화학식 2의 화합물, 이들의 약제학적으로 허용되는 염을 포함하는 혈관 재협착 치료 또는 예방용 조성물에 관한 것이다. 또한, 본 발명은 상기 조성물을 개체에 투여하여 혈관 협착을 제거하는 방법 및 상기 조성물의 국소 투여용 약물 전달 장치에 관한 것이다.
PCT/KR2009/001316 2008-03-18 2009-03-17 혈관 재협착 치료 또는 예방용 조성물 WO2009116774A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0024803 2008-03-18
KR1020080024803A KR100987557B1 (ko) 2008-03-18 2008-03-18 혈관 재협착 치료 또는 예방용 조성물

Publications (2)

Publication Number Publication Date
WO2009116774A2 WO2009116774A2 (ko) 2009-09-24
WO2009116774A3 true WO2009116774A3 (ko) 2009-11-26

Family

ID=41091379

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/001316 WO2009116774A2 (ko) 2008-03-18 2009-03-17 혈관 재협착 치료 또는 예방용 조성물

Country Status (2)

Country Link
KR (1) KR100987557B1 (ko)
WO (1) WO2009116774A2 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20120098489A (ko) * 2011-02-28 2012-09-05 이화여자대학교 산학협력단 피라졸 유도체를 포함하는 심혈관 질환 예방 및 치료용 조성물

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0667838B2 (ja) * 1985-12-25 1994-08-31 三菱化成株式会社 過酸化脂質生成抑制剤
WO2001009121A2 (en) * 1999-07-30 2001-02-08 Basf Aktiengesellschaft 2-pyrazolin-5-ones_as tyrosine kinase inhibitors
WO2001077080A2 (en) * 2000-04-07 2001-10-18 Kinetek Pharmaceuticals, Inc. Pyrazole compounds having anti proliferative activity
US20040254234A1 (en) * 2002-09-04 2004-12-16 Takayuki Tanaka Medicament for prevention and/or therapy of arterial wall disorder

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0667838A (ja) * 1992-08-21 1994-03-11 Toshiba Corp 表示処理装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0667838B2 (ja) * 1985-12-25 1994-08-31 三菱化成株式会社 過酸化脂質生成抑制剤
WO2001009121A2 (en) * 1999-07-30 2001-02-08 Basf Aktiengesellschaft 2-pyrazolin-5-ones_as tyrosine kinase inhibitors
WO2001077080A2 (en) * 2000-04-07 2001-10-18 Kinetek Pharmaceuticals, Inc. Pyrazole compounds having anti proliferative activity
US20040254234A1 (en) * 2002-09-04 2004-12-16 Takayuki Tanaka Medicament for prevention and/or therapy of arterial wall disorder

Also Published As

Publication number Publication date
KR100987557B1 (ko) 2010-10-12
WO2009116774A2 (ko) 2009-09-24
KR20090099671A (ko) 2009-09-23

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