WO2009113086A3 - Ibuprofen liquid fill formulation dosage form and its preparation - Google Patents

Ibuprofen liquid fill formulation dosage form and its preparation Download PDF

Info

Publication number
WO2009113086A3
WO2009113086A3 PCT/IN2009/000010 IN2009000010W WO2009113086A3 WO 2009113086 A3 WO2009113086 A3 WO 2009113086A3 IN 2009000010 W IN2009000010 W IN 2009000010W WO 2009113086 A3 WO2009113086 A3 WO 2009113086A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquid fill
preparation
dosage form
fill formulation
formulation dosage
Prior art date
Application number
PCT/IN2009/000010
Other languages
French (fr)
Other versions
WO2009113086A2 (en
Inventor
V. Vijay
Srinivas Raghupati
M. Krishna Prasad
V. Satyanarayana
Ashok Rampal
Original Assignee
Alkem Laboratories Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkem Laboratories Ltd. filed Critical Alkem Laboratories Ltd.
Publication of WO2009113086A2 publication Critical patent/WO2009113086A2/en
Publication of WO2009113086A3 publication Critical patent/WO2009113086A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to an ibuprofen liquid fill formulation, wherein the said liquid fill comprises ibuprofen with 50% of the particles not more than 50 microns and/or 90% of the particles not more than 100 microns and a solvent system comprising about 1% w/w to about 80% w/w polyethylene glycol, about 0 1% w/w to about 15% w/w of water and about 0.1% w/w to about 20% w/w of hydroxide species.
PCT/IN2009/000010 2008-01-07 2009-01-05 Ibuprofen liquid fill formulation, dosage form thereof and a process for its preparation WO2009113086A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN45/MUM/2008 2008-01-07
IN45MU2008 2008-01-07

Publications (2)

Publication Number Publication Date
WO2009113086A2 WO2009113086A2 (en) 2009-09-17
WO2009113086A3 true WO2009113086A3 (en) 2009-12-03

Family

ID=41065632

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2009/000010 WO2009113086A2 (en) 2008-01-07 2009-01-05 Ibuprofen liquid fill formulation, dosage form thereof and a process for its preparation

Country Status (1)

Country Link
WO (1) WO2009113086A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019224832A1 (en) * 2018-05-25 2019-11-28 Strides Shasun Limited Process for preparing pharmaceutical compositions resulting in reduction in overall fill volume for use with soft gelatin formulations
CN109820833B (en) * 2019-04-01 2022-02-01 人福普克药业（武汉）有限公司 Rapidly-dissolved ibuprofen soft capsule and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US5468502A (en) * 1994-12-20 1995-11-21 American Home Products Corporation Ibuprofen enhancing solvent system
WO2007035448A2 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US5468502A (en) * 1994-12-20 1995-11-21 American Home Products Corporation Ibuprofen enhancing solvent system
WO2007035448A2 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses

Also Published As

Publication number Publication date
WO2009113086A2 (en) 2009-09-17

Similar Documents

Publication Publication Date Title
WO2008008364A3 (en) Enhanced stability phenylephrine liquid compositions
WO2008109712A3 (en) Nanoparticle delivery systems for membrane-integrating peptides
EP3666076A3 (en) Agricultural pesticide compositions
PL2076244T3 (en) Aqueous systems for the preparation of lipid-based pharmaceutical compounds; compositions, methods, and uses thereof
WO2011138678A3 (en) Compositions, gels and foams with rheology modulators and uses thereof
WO2008060778A3 (en) Compositions having a performance indicator
WO2011161226A3 (en) Novel antibody formulation
WO2011090823A3 (en) Multi-surface acidic bathroom cleaning system
WO2007098128A3 (en) Phenylephrine-containing liquid formulations
WO2011117592A9 (en) Injector
WO2009100803A3 (en) Fluid compositions for colour electrophoretic displays
WO2012075507A3 (en) Disinfectant spray with indicator
WO2008151273A3 (en) Perfume systems
RS54588B1 (en) Liquid nasal spray containing low-dose naltrexone
WO2010006853A3 (en) Cosmetic sunscreen composite particules
EP3109307A3 (en) Perfume systems
WO2011025158A3 (en) Coacervate having an ionic polymer mixed with the adhesive protein of a mussel or of a species of the variome thereof
WO2010149727A3 (en) Injectable formulations containing asenapine and method of treatment using same
WO2010003567A3 (en) Fluorosurfactants
WO2011060363A3 (en) Cyclohexyl urea modulators of d2 receptors and/or d3 receptors
WO2010054286A3 (en) Substituted hydroxyphenylamine compounds
WO2013012666A3 (en) Compounds, methods of making, and methods of use
EP2343065A4 (en) The pharmaceutical composition containing ferulic acid and matrine compounds, the preparation and the use thereof
WO2008140496A3 (en) Preparation and purification of ionic liquids and precursors
WO2009046444A3 (en) Formulation for intranasal administration of diazepam

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09720915

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09720915

Country of ref document: EP

Kind code of ref document: A2