WO2009108307A3 - Utilisation d’anticorps monoclonaux anti-h8 à des fins de diagnostic - Google Patents

Utilisation d’anticorps monoclonaux anti-h8 à des fins de diagnostic Download PDF

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Publication number
WO2009108307A3
WO2009108307A3 PCT/US2009/001177 US2009001177W WO2009108307A3 WO 2009108307 A3 WO2009108307 A3 WO 2009108307A3 US 2009001177 W US2009001177 W US 2009001177W WO 2009108307 A3 WO2009108307 A3 WO 2009108307A3
Authority
WO
WIPO (PCT)
Prior art keywords
antigen
monoclonal antibodies
antibodies
diagnostic uses
recognize
Prior art date
Application number
PCT/US2009/001177
Other languages
English (en)
Other versions
WO2009108307A2 (fr
Inventor
Peter A. Rice
Sunita Gulati
Original Assignee
University Of Massachusetts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Massachusetts filed Critical University Of Massachusetts
Publication of WO2009108307A2 publication Critical patent/WO2009108307A2/fr
Publication of WO2009108307A3 publication Critical patent/WO2009108307A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/22—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Neisseriaceae (F), e.g. Acinetobacter

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L’invention a trait à l’utilisation, à des fins de diagnostic et de traitement, d’anticorps ou de fragments de liaison à un antigène qui reconnaissent l’antigène H8, une protéine membranaire externe des Neisseriae. Certains aspects de l’invention concernent des compositions pharmaceutiques et diagnostiques comprenant des anticorps ou des fragments de liaison à un antigène qui reconnaissent l’antigène H8. D’autres aspects concernent des kits de diagnostic comprenant des anticorps ou des fragments de liaison à un antigène qui reconnaissent l’antigène H8.
PCT/US2009/001177 2008-02-26 2009-02-25 Utilisation d’anticorps monoclonaux anti-h8 à des fins de diagnostic WO2009108307A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6722008P 2008-02-26 2008-02-26
US61/067,220 2008-02-26

Publications (2)

Publication Number Publication Date
WO2009108307A2 WO2009108307A2 (fr) 2009-09-03
WO2009108307A3 true WO2009108307A3 (fr) 2010-02-18

Family

ID=41016648

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/001177 WO2009108307A2 (fr) 2008-02-26 2009-02-25 Utilisation d’anticorps monoclonaux anti-h8 à des fins de diagnostic

Country Status (1)

Country Link
WO (1) WO2009108307A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10996218B2 (en) 2008-03-11 2021-05-04 Ournextbaby Llc Methods for chemotaxis / redox driven separation of X and Y chromosome bearing sperm and their insemination in gender specific menstrual cycles
WO2012036691A1 (fr) 2010-09-16 2012-03-22 Urobiologics Llc Utilisation d'urine de mammifère femelle pour la détermination de caractéristiques liées au sexe d'un fœtus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005592A1 (fr) * 1985-03-18 1986-09-25 National Research Development Corporation Proteine a activite antigenique et son utilisation pour le diagnostic de la blennorragie
US7081244B2 (en) * 1999-02-22 2006-07-25 Health Protection Agency Neisserial vaccine compositions and methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005592A1 (fr) * 1985-03-18 1986-09-25 National Research Development Corporation Proteine a activite antigenique et son utilisation pour le diagnostic de la blennorragie
US7081244B2 (en) * 1999-02-22 2006-07-25 Health Protection Agency Neisserial vaccine compositions and methods

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
E. C. GOTSCHLICH ET AL.: "Cloning of the structural genes of three H8 antigens and of protein III of Neisseria Gonorrhoeae.", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 164, September 1986 (1986-09-01), pages 868 - 881 *
J. G. CANNON ET AL.: "Monoclonal antibody that recognizes an outer membrane antigen common to the pathogenic Neisseria species but not to most nonpathogenic Neisseria Species.", INFECTION AND IMMUNITY., vol. 43, no. 3, March 1984 (1984-03-01), pages 994 - 999 *
P. J. HITCHCOCK ET AL.: "Analysis of gonococcal H8 antigen.", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 162, December 1985 (1985-12-01), pages 2017 - 2034 *

Also Published As

Publication number Publication date
WO2009108307A2 (fr) 2009-09-03

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