WO2009104961A3 - Process for the preparation of a dichloropropanol product - Google Patents

Process for the preparation of a dichloropropanol product Download PDF

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Publication number
WO2009104961A3
WO2009104961A3 PCT/NL2009/050072 NL2009050072W WO2009104961A3 WO 2009104961 A3 WO2009104961 A3 WO 2009104961A3 NL 2009050072 W NL2009050072 W NL 2009050072W WO 2009104961 A3 WO2009104961 A3 WO 2009104961A3
Authority
WO
WIPO (PCT)
Prior art keywords
product
hydrochloric acid
preparation
dichloropropanol
chloropropane
Prior art date
Application number
PCT/NL2009/050072
Other languages
French (fr)
Other versions
WO2009104961A2 (en
Inventor
Bouwe De Jong
Magnus Kristian MALMSTRÖM
Original Assignee
Bouwe De Jong
Malmstroem Magnus Kristian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bouwe De Jong, Malmstroem Magnus Kristian filed Critical Bouwe De Jong
Publication of WO2009104961A2 publication Critical patent/WO2009104961A2/en
Publication of WO2009104961A3 publication Critical patent/WO2009104961A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • C07D301/24—Synthesis of the oxirane ring by splitting off HAL—Y from compounds containing the radical HAL—C—C—OY
    • C07D301/26—Y being hydrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to a process for the preparation of a dichloropropanol product, wherein the dichloropropanol product comprises a mixture of 1,2-dichloropropan-3-ol and 1,3-dichloropropan-2-ol, said process comprising the steps of: (a) contacting glycerol with hydrochloric acid in a molar ratio of glycerol to hydrochloric acid of about less than 1 to about 100 to form a first product mixture comprising l-chloropropane-2,3-diol as a major constituent; and (b) contacting said first product mixture comprising 1-chloropropane-2,3-diol as a major constituent with hydrochloric acid in a molar ratio of 1-chloropropane-2,3- diol to hydrochloric acid of about less than 1 to about 100 to form the dichloropropanol product.
PCT/NL2009/050072 2008-02-21 2009-02-19 Process for the preparation of a dichloropropanol product WO2009104961A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3029508P 2008-02-21 2008-02-21
US61/030,295 2008-02-21

Publications (2)

Publication Number Publication Date
WO2009104961A2 WO2009104961A2 (en) 2009-08-27
WO2009104961A3 true WO2009104961A3 (en) 2009-10-15

Family

ID=40677669

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2009/050072 WO2009104961A2 (en) 2008-02-21 2009-02-19 Process for the preparation of a dichloropropanol product

Country Status (1)

Country Link
WO (1) WO2009104961A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101792424B (en) * 2010-04-06 2012-02-29 山东海力化工股份有限公司 Environment-friendly preparation process for producing epoxy chloropropane by complexation and extraction

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL215730B1 (en) 2011-01-10 2014-01-31 Inst Ciezkiej Syntezy Orga Process for the preparation of dichloropropanols from glycerine
CN102391072B (en) * 2011-09-23 2014-01-15 中国天辰工程有限公司 Method for separating oil-phase dichloropropanol from mixed aqueous solution of dichloropropanol and chlorine hydride
CN111875511A (en) * 2020-07-13 2020-11-03 山东泰和水处理科技股份有限公司 Preparation method of biquaternary ammonium salt intermediate
CN111718270B (en) * 2020-07-13 2023-08-22 山东泰和科技股份有限公司 Synthesis method of biquaternary ammonium salt intermediate
CN114849614B (en) * 2022-05-24 2023-11-03 山东绿色海洋化工研究院有限公司 Micro-reaction method for preparing higher halogenated aliphatic hydrocarbon by utilizing micro-reaction system
CN115097022B (en) * 2022-05-30 2023-06-27 浙江万盛股份有限公司 Method for measuring impurity content in dichloropropanol preparation process by glycerol method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE263106C (en) *
WO2005021476A1 (en) * 2003-09-01 2005-03-10 Spolek Pro Chemickou A Hutni Vyrobu, Akciova Spolecnost Method of preparing dichloropropanols from glycerine
WO2005054167A1 (en) * 2003-11-20 2005-06-16 Solvay (Société Anonyme) Process for producing dichloropropanol from glycerol, the glycerol coming eventually from the conversion of animal fats in the manufacture of biodiesel

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE263106C (en) *
WO2005021476A1 (en) * 2003-09-01 2005-03-10 Spolek Pro Chemickou A Hutni Vyrobu, Akciova Spolecnost Method of preparing dichloropropanols from glycerine
WO2005054167A1 (en) * 2003-11-20 2005-06-16 Solvay (Société Anonyme) Process for producing dichloropropanol from glycerol, the glycerol coming eventually from the conversion of animal fats in the manufacture of biodiesel

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; 1910, XP002539323, Database accession no. Reaction ID:116249 *
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; 1950, XP002539322, Database accession no. Reaction ID:214069 *
FODOR, ARCHIVES OF BIOCHEMISTRY, vol. 28, 1950, pages 274 - 275 *
GIBSON G P: "THE PREPARATION, PROPERTIES AND USES OF GLYCEROL DERIVATIVES. Part III. THE CHLOROHYDRINS", CHEMISTRY & INDUSTRY, SOCIETY OF CHEMICAL INDUSTRY. LONDON, GB, 1 January 1931 (1931-01-01), pages 949 - 970, XP009042263, ISSN: 0009-3068 *
GRUEN, CHEMISCHE BERICHTE, vol. 43, 1910, pages 1290 *
L. NIEMILOWICZ: "Zur Kenntnis einger cholinartiger Verbindungen", MONATSHEFTE FÜR CHEMIE, vol. 7, 1886, pages 241 - 254, XP002539324 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101792424B (en) * 2010-04-06 2012-02-29 山东海力化工股份有限公司 Environment-friendly preparation process for producing epoxy chloropropane by complexation and extraction

Also Published As

Publication number Publication date
WO2009104961A2 (en) 2009-08-27

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