WO2009093007A3 - Immune modulation by regioselectively modified glycosides - Google Patents

Immune modulation by regioselectively modified glycosides Download PDF

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Publication number
WO2009093007A3
WO2009093007A3 PCT/GB2009/000131 GB2009000131W WO2009093007A3 WO 2009093007 A3 WO2009093007 A3 WO 2009093007A3 GB 2009000131 W GB2009000131 W GB 2009000131W WO 2009093007 A3 WO2009093007 A3 WO 2009093007A3
Authority
WO
WIPO (PCT)
Prior art keywords
immune modulation
modified glycosides
regioselectively modified
regioselectively
glycosides
Prior art date
Application number
PCT/GB2009/000131
Other languages
French (fr)
Other versions
WO2009093007A2 (en
Inventor
Eng-Kiat Lim
Paul Kaye
Dianna Joy Bowles
Original Assignee
The University Of York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of York filed Critical The University Of York
Publication of WO2009093007A2 publication Critical patent/WO2009093007A2/en
Publication of WO2009093007A3 publication Critical patent/WO2009093007A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

We describe the use of regioselectively glycosylated glycoside scaffolds in the modulation of the immune system.
PCT/GB2009/000131 2008-01-21 2009-01-16 Immune modulation by regioselectively modified glycosides WO2009093007A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0801032.4 2008-01-21
GBGB0801032.4A GB0801032D0 (en) 2008-01-21 2008-01-21 Immune modulation

Publications (2)

Publication Number Publication Date
WO2009093007A2 WO2009093007A2 (en) 2009-07-30
WO2009093007A3 true WO2009093007A3 (en) 2009-11-26

Family

ID=39166075

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2009/000131 WO2009093007A2 (en) 2008-01-21 2009-01-16 Immune modulation by regioselectively modified glycosides

Country Status (2)

Country Link
GB (1) GB0801032D0 (en)
WO (1) WO2009093007A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012086812A1 (en) * 2010-12-22 2012-06-28 味の素株式会社 Glycoside compound
CN102949404B (en) * 2011-08-16 2016-09-14 中国医学科学院药物研究所 Vanillic acid glucoside derivative purposes in treatment of systemic autoimmune disease
WO2013128423A1 (en) * 2012-03-02 2013-09-06 Institut National De La Sante Et De La Recherche Medicale Use of a glycosylated-modified tetrafunctional non-ionic amphiphilic block copolymer as immune adjuvant
KR101392988B1 (en) 2012-09-13 2014-05-09 건국대학교 산학협력단 Engineered Esherichia coli expressing uridine-diphosphate(UDP)-dependent glycosyltransferase and Synthesis of quercetin 3,7-di-O-rhamnoside from the same
BR112015013651B1 (en) 2012-12-27 2020-03-24 Kimberly-Clark Worldwide, Inc. FARNESOL ANALOG, SCARF, ABSORBENT ARTICLE, AND FORMATION METHOD OF A FARNESOL ANALOG
WO2014101049A1 (en) 2012-12-27 2014-07-03 Kimberly-Clark Worldwide, Inc. Water soluble essential oils and their use
WO2015114584A1 (en) * 2014-01-31 2015-08-06 Ghimas S.P.A. Polydatin for the treatment of hiv in patients
WO2019135257A1 (en) 2018-01-03 2019-07-11 Council Of Scientific And Industrial Research Artemisinic acid glycoconjugate compounds, process for preparation and use thereof
US11643428B2 (en) * 2018-02-06 2023-05-09 Shanghai Pharmaceuticals Holding Co., Ltd. Therapeutic drug for neurodegenerative disease and application thereof
KR102187233B1 (en) * 2018-12-07 2020-12-04 경희대학교 산학협력단 Composition for immunity enhancement or anti-inflammatory comprising flavonoid from Brugmansia arborea
CN111658631A (en) * 2020-06-11 2020-09-15 广东盛普生命科技有限公司 Application of gallic acid and its derivatives and structural analogs in preparing anti-coronavirus medicine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002032410A2 (en) * 2000-10-19 2002-04-25 Imperial College Innovations Limited Pharmaceutical composition comprising resveratrol for treating inflammatory respiratory disorders
WO2007034190A2 (en) * 2005-09-21 2007-03-29 The University Of York Regioselective glycosylation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002032410A2 (en) * 2000-10-19 2002-04-25 Imperial College Innovations Limited Pharmaceutical composition comprising resveratrol for treating inflammatory respiratory disorders
WO2007034190A2 (en) * 2005-09-21 2007-03-29 The University Of York Regioselective glycosylation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FENG YONG-HONG ET AL: "Low dose of resveratrol enhanced immune response of mice", ACTA PHARMACOLOGICA SINICA, WILEY INTERSCIENCE, vol. 23, no. 10, 1 October 2002 (2002-10-01), pages 893 - 897, XP002378877, ISSN: 1671-4083 *
LAI-YI WANG ET AL: "Resveratrol glucuronides as the metabolites of resveratrol in humans: Characterization, synthesis, and anti-HIV activity", JOURNAL OF PHARMACEUTICAL SCIENCE, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, US, vol. 93, no. 10, 23 July 2004 (2004-07-23), pages 2448 - 2457, XP009120641, ISSN: 0022-3549 *
LU WEI ET AL: "Therapeutic dendritic-cell vaccine for simian AIDS", NATURE MEDICINE, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 9, no. 1, 1 January 2003 (2003-01-01), pages 27 - 32, XP002366697, ISSN: 1078-8956 *

Also Published As

Publication number Publication date
GB0801032D0 (en) 2008-02-27
WO2009093007A2 (en) 2009-07-30

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