WO2009088442A3 - Isomerases and epimerases and methods of using - Google Patents

Isomerases and epimerases and methods of using Download PDF

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Publication number
WO2009088442A3
WO2009088442A3 PCT/US2008/013968 US2008013968W WO2009088442A3 WO 2009088442 A3 WO2009088442 A3 WO 2009088442A3 US 2008013968 W US2008013968 W US 2008013968W WO 2009088442 A3 WO2009088442 A3 WO 2009088442A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
epimerases
isomerases
polypeptides
racemase
Prior art date
Application number
PCT/US2008/013968
Other languages
French (fr)
Other versions
WO2009088442A2 (en
Inventor
Mervyn L. De Souza
Wei Niu
Jose M. Laplaza
Christopher Solheid
Sherry R. Kollmann
Joshua M. Lundorff
Paula M. Hicks
Sara C. Mcfarlan
Fernando A. Sanchez-Riera
David P. Weiner
Ellen Burke
Peter Luginbuhl
Analia Bueno
Joslin Cuenca
Original Assignee
Cargill, Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill, Incorporated filed Critical Cargill, Incorporated
Publication of WO2009088442A2 publication Critical patent/WO2009088442A2/en
Publication of WO2009088442A3 publication Critical patent/WO2009088442A3/en
Priority to US12/828,714 priority Critical patent/US20110045547A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides for isomerase (e.g., racemase) and epimerase polypeptides and nucleic acids encoding such polypeptides. Also provided are methods of using such isomerase (e.g., racemase) and epimerase nucleic acids and polypeptides.
PCT/US2008/013968 2008-01-03 2008-12-22 Isomerases and epimerases and methods of using WO2009088442A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/828,714 US20110045547A1 (en) 2008-01-03 2010-07-01 Isomerases and epimerases and methods of using

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1884508P 2008-01-03 2008-01-03
US61/018,845 2008-01-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/049599 Continuation WO2011002469A1 (en) 2008-01-03 2009-07-02 Isomerases and epimerases and methods of using

Publications (2)

Publication Number Publication Date
WO2009088442A2 WO2009088442A2 (en) 2009-07-16
WO2009088442A3 true WO2009088442A3 (en) 2010-03-18

Family

ID=40853655

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/013968 WO2009088442A2 (en) 2008-01-03 2008-12-22 Isomerases and epimerases and methods of using

Country Status (1)

Country Link
WO (1) WO2009088442A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050095670A1 (en) * 2002-03-01 2005-05-05 Hajime Ikeda Amino acid racemase having low substrate specificity and process for producing racemic amino acid
US20060252135A1 (en) * 2005-04-26 2006-11-09 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US20080020434A1 (en) * 2005-04-26 2008-01-24 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050095670A1 (en) * 2002-03-01 2005-05-05 Hajime Ikeda Amino acid racemase having low substrate specificity and process for producing racemic amino acid
US20060252135A1 (en) * 2005-04-26 2006-11-09 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US20080020434A1 (en) * 2005-04-26 2008-01-24 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 2 October 2001 (2001-10-02), DECKERT ET AL: "UFP0001 protein aq_274", Database accession no. O66631 *
DATABASE GENBANK [online] 22 December 2005 (2005-12-22), DECKERT ET AL: "Aquifex aeolicus VFS, complete genome", Database accession no. AE000657 *
DATABASE INTERPRO [online] 1991, "Alanine racemase, N-terminal", Database accession no. IPR001608 *

Also Published As

Publication number Publication date
WO2009088442A2 (en) 2009-07-16

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