WO2009086333A3 - Methods and compositions relatin to antibodies that bind a protein reticulon 3 - Google Patents

Methods and compositions relatin to antibodies that bind a protein reticulon 3 Download PDF

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Publication number
WO2009086333A3
WO2009086333A3 PCT/US2008/088082 US2008088082W WO2009086333A3 WO 2009086333 A3 WO2009086333 A3 WO 2009086333A3 US 2008088082 W US2008088082 W US 2008088082W WO 2009086333 A3 WO2009086333 A3 WO 2009086333A3
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WO
WIPO (PCT)
Prior art keywords
antibodies
reticulon
bind
protein
relatin
Prior art date
Application number
PCT/US2008/088082
Other languages
French (fr)
Other versions
WO2009086333A2 (en
Inventor
Nobuko Uchida
Stanley Tamaki
Yakop Jacobs
Original Assignee
Stemcells California, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemcells California, Inc filed Critical Stemcells California, Inc
Publication of WO2009086333A2 publication Critical patent/WO2009086333A2/en
Publication of WO2009086333A3 publication Critical patent/WO2009086333A3/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Antibodies that bind a protein Reticulon 3 are disclosed. Preferably, the antibodies are monoclonal antibodies of an IgGl isotype and bind human Reticulon 3. In a preferred embodiment, an antibody of the invention binds an epitope recognized by a monoclonal antibody SC121, produced by a hybridoma SC121 (ATTC Accession No. PTA-8617). Pharmaceutical compositions comprising the antibodies of the invention are also disclosed. The antibodies of the invention are useful for isolating, characterizing, and tracking the progeny of human cells. Nucleic acid molecules encoding anti-Reticulon 3 antibodies, or portions thereof, as well as expression vectors and host cells incorporating said nucleic acid molecules, are also encompassed by the invention.
PCT/US2008/088082 2007-12-20 2008-12-22 Antibodies and methods for identifying and tracking engraftment, migratation, and differentiation of human stem, progenitor, and engrafting cell populations WO2009086333A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US892307P 2007-12-20 2007-12-20
US61/008,923 2007-12-20

Publications (2)

Publication Number Publication Date
WO2009086333A2 WO2009086333A2 (en) 2009-07-09
WO2009086333A3 true WO2009086333A3 (en) 2010-01-07

Family

ID=40825074

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/088082 WO2009086333A2 (en) 2007-12-20 2008-12-22 Antibodies and methods for identifying and tracking engraftment, migratation, and differentiation of human stem, progenitor, and engrafting cell populations

Country Status (1)

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WO (1) WO2009086333A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101935338A (en) * 2010-09-10 2011-01-05 深圳华大基因科技有限公司 Reticuloprotein epitope, anti-reticuloprotein antibody and application thereof
JP6836990B2 (en) 2014-11-26 2021-03-03 アクセラレイテッド・バイオサイエンシズ・コーポレーション Induced hepatocytes and their use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060099651A1 (en) * 2002-08-27 2006-05-11 Nobuko Uchida Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060099651A1 (en) * 2002-08-27 2006-05-11 Nobuko Uchida Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations

Also Published As

Publication number Publication date
WO2009086333A2 (en) 2009-07-09

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