WO2009083975A3 - Small molecules and protein analysis devices based on molecular imprinted polymers - Google Patents

Small molecules and protein analysis devices based on molecular imprinted polymers Download PDF

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Publication number
WO2009083975A3
WO2009083975A3 PCT/IL2008/001688 IL2008001688W WO2009083975A3 WO 2009083975 A3 WO2009083975 A3 WO 2009083975A3 IL 2008001688 W IL2008001688 W IL 2008001688W WO 2009083975 A3 WO2009083975 A3 WO 2009083975A3
Authority
WO
WIPO (PCT)
Prior art keywords
small molecules
devices based
protein analysis
analysis devices
imprinted polymers
Prior art date
Application number
PCT/IL2008/001688
Other languages
French (fr)
Other versions
WO2009083975A2 (en
Inventor
Raphael Levi
Ido Margalit
Yarden Dloomy
Original Assignee
Infigo Diagnostics Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infigo Diagnostics Ltd. filed Critical Infigo Diagnostics Ltd.
Priority to EP08868717A priority Critical patent/EP2245135A4/en
Priority to CN2008801268886A priority patent/CN101945990A/en
Priority to JP2010540221A priority patent/JP2011508233A/en
Publication of WO2009083975A2 publication Critical patent/WO2009083975A2/en
Publication of WO2009083975A3 publication Critical patent/WO2009083975A3/en
Priority to IL206618A priority patent/IL206618A0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2600/00—Assays involving molecular imprinted polymers/polymers created around a molecular template

Abstract

Devices, methods and kits for rapid and simple determination of target molecules, including small molecules, polypeptides, proteins, cells and infectious disease agents in liquid samples that are capable of real-time measurement of these entities in fluid samples that are highly selective, highly sensitive, simple to operate, low cost, and portable. The devices, methods and kits also provide, in at least some embodiments, the use of MIPs in a flow through or lateral flow device.
PCT/IL2008/001688 2007-12-27 2008-12-28 Small molecules and protein analysis devices based on molecular imprinted polymers WO2009083975A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP08868717A EP2245135A4 (en) 2007-12-27 2008-12-28 Small molecules and protein analysis devices based on molecular imprinted polymers
CN2008801268886A CN101945990A (en) 2007-12-27 2008-12-28 Small molecules and protein analysis devices based on molecular imprinted polymers
JP2010540221A JP2011508233A (en) 2007-12-27 2008-12-28 Small molecule and protein analysis devices based on molecularly imprinted polymers
IL206618A IL206618A0 (en) 2007-12-27 2010-06-24 Small molecules and protein analysis devices based on molecular imprinted polymers

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1682907P 2007-12-27 2007-12-27
US61/016,829 2007-12-27
US2746208P 2008-02-10 2008-02-10
US61/027,462 2008-02-10

Publications (2)

Publication Number Publication Date
WO2009083975A2 WO2009083975A2 (en) 2009-07-09
WO2009083975A3 true WO2009083975A3 (en) 2010-03-11

Family

ID=40824816

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2008/001688 WO2009083975A2 (en) 2007-12-27 2008-12-28 Small molecules and protein analysis devices based on molecular imprinted polymers

Country Status (4)

Country Link
EP (1) EP2245135A4 (en)
JP (1) JP2011508233A (en)
CN (1) CN101945990A (en)
WO (1) WO2009083975A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011010304A2 (en) * 2009-07-23 2011-01-27 Infigo Diagnostics Ltd. Method for preparing molecularly imprinted polymers and uses thereof
CN102169120B (en) * 2010-02-25 2014-09-17 艾博生物医药(杭州)有限公司 Detector
CN101816927B (en) * 2010-04-30 2012-11-14 南开大学 Temperature-sensitive protein molecular engram monolithic column and preparation method and application thereof
WO2012138429A1 (en) * 2011-02-25 2012-10-11 University Of South Florida Molecularly imprinted polymers having affinity for natriuretic peptides
CN102507261B (en) * 2011-10-20 2015-06-03 东北大学 Method for selectively and quantitatively collecting arsenic in water environment
CN102417558B (en) * 2011-11-21 2013-09-04 嘉兴学院 Magnetic molecularly imprinted polymer for separating atrazine, and preparation method for magnetic molecularly imprinted polymer
JP6298761B2 (en) * 2012-06-06 2018-03-20 日本碍子株式会社 Chromatographic apparatus and use thereof
KR102630880B1 (en) 2014-03-07 2024-01-29 더 리전트 오브 더 유니버시티 오브 캘리포니아 Devices for integrating analyte extraction, concentration and detection
CN105004855B (en) * 2014-04-16 2017-05-31 万冰 A kind of lateral flow detects test-strips
JP2017150815A (en) * 2014-05-29 2017-08-31 株式会社日立製作所 Clinical examination kit and chemical substance detection method
US10471011B2 (en) 2014-12-05 2019-11-12 Toshifumi Takeuchi In vivo stealth nanoparticle
JP2016141665A (en) * 2015-02-04 2016-08-08 オルテック インコーポレイテッド Aflatoxin template, molecular imprint polymer, and methods of producing and using the same
KR20180052122A (en) 2015-09-04 2018-05-17 더 리전트 오브 더 유니버시티 오브 캘리포니아 Methods and apparatus for clinical analyte collection, extraction, concentration and detection
US11549948B2 (en) 2016-03-15 2023-01-10 Mipsalus Aps Detection method and means therefor
US10835898B2 (en) * 2016-03-18 2020-11-17 Quidel Corporation Microfluidic device, system and method
CN107478759A (en) * 2016-06-08 2017-12-15 南京医科大学 It is used for the detection method of arasaponin metabolite group in rat excrement based on molecular imprinting nanometer magnetic bead and mass spectrometry
WO2017214315A1 (en) 2016-06-09 2017-12-14 The Regents Of The University Of California Biomarker concentration and signal amplification for use in paper-based immunoassays and a single platform for extracting, concentrating, and amplifying dna
WO2018039139A1 (en) 2016-08-22 2018-03-01 The Regents Of The University Of California Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
CN106526176A (en) * 2016-12-05 2017-03-22 无锡艾科瑞思产品设计与研究有限公司 Multifunctional fluorescence-immunochromatography rapid quantitative detection strip
CN106645109B (en) * 2016-12-29 2019-11-26 Tcl集团股份有限公司 A kind of method, apparatus and system detecting hormone
CN106872689B (en) * 2017-01-10 2019-02-15 宁波大学 A kind of quickly measurement remaining bionical enzyme-linked immune detection method of sulfa antibiotics
WO2018183211A1 (en) 2017-03-27 2018-10-04 The Regents Of The University Of California Semi-quantitative lateral-flow immunoassay for the detection of csf leaks
CN111116823B (en) * 2018-10-31 2021-01-05 华中科技大学 Preparation method and application of material for screening thyroxin interferon
KR102352617B1 (en) 2019-12-26 2022-01-19 프리시젼바이오 주식회사 Method for producing test strips for multiple immunoassays and test strirps manufactured by the same
CN115960377B (en) * 2022-12-19 2023-07-21 北京工商大学 Specific fluorescent indicator sheet and preparation method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060177882A1 (en) * 2005-02-04 2006-08-10 Samad Talebpour Immunoassays with enhanced selectivity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85101019A (en) * 1984-06-12 1987-01-10 田纳西大学研究公司 Assaying immunoliposome is analysed-method and product
US6461873B1 (en) * 1999-03-18 2002-10-08 Daniel Catania Caffeine detector
SE0001877D0 (en) * 2000-05-22 2000-05-22 Klaus Mosbach Molecular imprinting
DE10042023C2 (en) * 2000-08-08 2003-04-10 Biognostic Ag Capsules that encapsulate solid particles of signal-generating substances and their use in bioassays for the detection of target molecules in a sample
WO2008007359A2 (en) * 2006-07-09 2008-01-17 Infigo Diagnostics Ltd. Rapid diagnostic devices based on molecular imprinted polymers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060177882A1 (en) * 2005-02-04 2006-08-10 Samad Talebpour Immunoassays with enhanced selectivity

Also Published As

Publication number Publication date
CN101945990A (en) 2011-01-12
EP2245135A2 (en) 2010-11-03
WO2009083975A2 (en) 2009-07-09
EP2245135A4 (en) 2011-01-12
JP2011508233A (en) 2011-03-10

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