WO2009079629A3 - A cardiac output monitor probe and calibrator - Google Patents

A cardiac output monitor probe and calibrator Download PDF

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Publication number
WO2009079629A3
WO2009079629A3 PCT/US2008/087457 US2008087457W WO2009079629A3 WO 2009079629 A3 WO2009079629 A3 WO 2009079629A3 US 2008087457 W US2008087457 W US 2008087457W WO 2009079629 A3 WO2009079629 A3 WO 2009079629A3
Authority
WO
WIPO (PCT)
Prior art keywords
cardiac output
calibrator
dialysis
probe
patient
Prior art date
Application number
PCT/US2008/087457
Other languages
French (fr)
Other versions
WO2009079629A2 (en
Inventor
Eduardo H. Rubinstein
Daniel P. Holschneider
Jean-Michel I. Maarek
Alan Eskovitz
Sudeep Deeshpande
Original Assignee
Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California filed Critical Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California
Publication of WO2009079629A2 publication Critical patent/WO2009079629A2/en
Publication of WO2009079629A3 publication Critical patent/WO2009079629A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6491—Measuring fluorescence and transmission; Correcting inner filter effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

A non-invasive system and method for determination of cardiac output and blood volume of a patient. A dialysis probe wrapped around a blood tubing of the dialysis machine attached to the patient, to illuminate and detect the corresponding light effects. A probe calibrator to calibrate the dialysis probe prior to dialysis process. The cardiac output is determined on a patient undergoing hemodialysis based on the detected light effects.
PCT/US2008/087457 2007-12-18 2008-12-18 A cardiac output monitor probe and calibrator WO2009079629A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1454607P 2007-12-18 2007-12-18
US61/014,546 2007-12-18

Publications (2)

Publication Number Publication Date
WO2009079629A2 WO2009079629A2 (en) 2009-06-25
WO2009079629A3 true WO2009079629A3 (en) 2010-01-28

Family

ID=40796140

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/087457 WO2009079629A2 (en) 2007-12-18 2008-12-18 A cardiac output monitor probe and calibrator

Country Status (1)

Country Link
WO (1) WO2009079629A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT513863B1 (en) 2013-02-15 2014-12-15 Vwm Gmbh Method and device for determining a concentration of a fluorescent substance in a medium
US9702762B2 (en) 2013-03-15 2017-07-11 Lightlab Imaging, Inc. Calibration and image processing devices, methods, and systems
CN108024713B (en) * 2015-05-26 2021-08-17 Lvl技术公司 Apparatus and method for determining a level of a biological indicator in tissue
US10996170B2 (en) * 2016-03-14 2021-05-04 Massachusetts Institute Of Technology Device and method for imaging shortwave infrared fluorescence

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5701902A (en) * 1994-09-14 1997-12-30 Cedars-Sinai Medical Center Spectroscopic burn injury evaluation apparatus and method
WO2007136521A2 (en) * 2006-05-17 2007-11-29 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution for hemodialysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5701902A (en) * 1994-09-14 1997-12-30 Cedars-Sinai Medical Center Spectroscopic burn injury evaluation apparatus and method
WO2007136521A2 (en) * 2006-05-17 2007-11-29 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution for hemodialysis

Also Published As

Publication number Publication date
WO2009079629A2 (en) 2009-06-25

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