WO2009078036A3 - Process and intermediate of letrozole - Google Patents

Process and intermediate of letrozole Download PDF

Info

Publication number
WO2009078036A3
WO2009078036A3 PCT/IN2008/000801 IN2008000801W WO2009078036A3 WO 2009078036 A3 WO2009078036 A3 WO 2009078036A3 IN 2008000801 W IN2008000801 W IN 2008000801W WO 2009078036 A3 WO2009078036 A3 WO 2009078036A3
Authority
WO
WIPO (PCT)
Prior art keywords
letrozole
involving
formula
preparation
relates
Prior art date
Application number
PCT/IN2008/000801
Other languages
French (fr)
Other versions
WO2009078036A2 (en
Inventor
B. Vishnukant
Original Assignee
Shilpa Medicare Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shilpa Medicare Ltd. filed Critical Shilpa Medicare Ltd.
Publication of WO2009078036A2 publication Critical patent/WO2009078036A2/en
Publication of WO2009078036A3 publication Critical patent/WO2009078036A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
    • C07C257/06—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers having carbon atoms of imino-carboxyl groups bound to hydrogen atoms, to acyclic carbon atoms, or to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention relates to a process for the preparation of Letrozole involving the use of novel intermediate of Formula I.
PCT/IN2008/000801 2007-12-11 2008-12-01 Process and intermediate of letrozole WO2009078036A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2971/CHE/2007 2007-12-11
IN2971CH2007 2007-12-11

Publications (2)

Publication Number Publication Date
WO2009078036A2 WO2009078036A2 (en) 2009-06-25
WO2009078036A3 true WO2009078036A3 (en) 2009-10-22

Family

ID=40795972

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2008/000801 WO2009078036A2 (en) 2007-12-11 2008-12-01 Process and intermediate of letrozole

Country Status (1)

Country Link
WO (1) WO2009078036A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103664810B (en) * 2013-12-11 2016-09-14 深圳劲创生物技术有限公司 A kind of technique synthesizing letrozole

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070100149A1 (en) * 2005-11-02 2007-05-03 Palle Venkata Raghavendra A Process for preparing letrozole
US20070112202A1 (en) * 2005-11-14 2007-05-17 Chemagis Ltd. Letrozole production process
WO2007144896A1 (en) * 2006-06-13 2007-12-21 Natco Pharma Limited A method of manufacture of letrozole

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070100149A1 (en) * 2005-11-02 2007-05-03 Palle Venkata Raghavendra A Process for preparing letrozole
US20070112202A1 (en) * 2005-11-14 2007-05-17 Chemagis Ltd. Letrozole production process
WO2007144896A1 (en) * 2006-06-13 2007-12-21 Natco Pharma Limited A method of manufacture of letrozole

Also Published As

Publication number Publication date
WO2009078036A2 (en) 2009-06-25

Similar Documents

Publication Publication Date Title
WO2011138281A3 (en) Process for the preparation of dithiine tetracarboxydiimides
WO2007115821A3 (en) Organic compounds
WO2009156462A3 (en) Organic compounds
WO2007093627A3 (en) Biocidal composition
WO2011077043A3 (en) Phenol derivatives and pharmaceutical or cosmetic use thereof
WO2009026176A3 (en) Antiinfective flavononol compounds and methods of use thereof
WO2008149345A3 (en) Tri-aryl compounds and compositions comprising the same
WO2009124962A3 (en) Sulfonamides
WO2008058118A3 (en) Preparation of montelukast and its salts
WO2008053334A3 (en) An improved process for preparing rosuvastatin calcium
EA200900090A1 (en) BENZYLAMINES, METHOD OF THEIR PRODUCTION AND THEIR APPLICATION AS ANTI-INFLAMMATORY MEANS
WO2009074247A8 (en) Novel 2-aryl-thiazole-4-carboxamide derivatives, production thereof, and use thereof as a medicament
PL2137206T3 (en) Process for the preparation of tauroursodesoxycholic acid
TW200728310A (en) Process for the preparation of ferri-succinylcasein
WO2007130821A3 (en) Mglur5 modulators ii
WO2008032099A3 (en) Process for the preparation of montelukast, and intermediates therefor
WO2006134499A3 (en) 2-(1h-indolylsulfanyl)-aryl amine derivatives
WO2011058525A3 (en) Processes for the preparation of erlotinib hydrochloride form a and erlotinib hydrochloride form b
HK1144682A1 (en) Process for the preparation of alkyl 3,3-dialkoxypropionates 33-
WO2010015656A3 (en) Alkoxypyrazoles and the process for their preparation
WO2010077730A3 (en) Indanone inhibitors of acetylcholinesterase
WO2010098583A2 (en) Novel method for preparing statin compounds or salts thereof, and intermediate compounds used in same
WO2011073370A3 (en) Use of 2,3-dihydroxypropyl dodecanoate for treating seborrhea
WO2008019030A3 (en) Modified azole compounds as antiinfective agents
WO2008059519A3 (en) A process for the preparation of intermediates of rosuvastatin

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08863326

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08863326

Country of ref document: EP

Kind code of ref document: A2