WO2009068913A3 - Bioactive and resorbable soybean-based biomaterials - Google Patents

Bioactive and resorbable soybean-based biomaterials Download PDF

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Publication number
WO2009068913A3
WO2009068913A3 PCT/GB2008/051117 GB2008051117W WO2009068913A3 WO 2009068913 A3 WO2009068913 A3 WO 2009068913A3 GB 2008051117 W GB2008051117 W GB 2008051117W WO 2009068913 A3 WO2009068913 A3 WO 2009068913A3
Authority
WO
WIPO (PCT)
Prior art keywords
soybean
biomaterials
bioactive
surgical
biomedical
Prior art date
Application number
PCT/GB2008/051117
Other languages
French (fr)
Other versions
WO2009068913A2 (en
Inventor
Luigi Ambrosio
Luigi Nicolais
Jonathan Peter Salvage
Matteo Santin
Guy Standen
Original Assignee
University Of Brighton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Brighton filed Critical University Of Brighton
Priority to EP08853269.2A priority Critical patent/EP2222347B1/en
Priority to ES08853269T priority patent/ES2433207T3/en
Priority to JP2010535459A priority patent/JP2011504406A/en
Priority to US12/744,848 priority patent/US20110027364A1/en
Publication of WO2009068913A2 publication Critical patent/WO2009068913A2/en
Publication of WO2009068913A3 publication Critical patent/WO2009068913A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3637—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the origin of the biological material other than human or animal, e.g. plant extracts, algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

Bioactive and resorbable soybean-based biomaterials A method of producing a soybean-based biomaterial which is suitable for use in a biomedical product, the method comprising: defatting soy flour; either prior to or at the same time as, performing a solvent extraction; to produce a biomaterial comprising variable levels of soy proteins, carbohydrates and isoflavones. The resulting biomaterials have a range of biomedical uses and are particularly desirable because of their isoflavone content. Examples of biomedical products containing the biomaterials include wound dressings; scaffolds for tissue engineering; fillers or implants for use in surgery; temporary barriers for use in dental or surgical procedures or to prevent post-surgical tissue adherence; carriers for the delivery of drugs, bioactive peptides or plasmids; anti-inflammatory agents; coatings for wound dressings or for dental, medical, surgical or veterinary devices or implants; and compositions for soothing skin or gum irritation.
PCT/GB2008/051117 2007-11-26 2008-11-26 Bioactive and resorbable soybean-based biomaterials WO2009068913A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP08853269.2A EP2222347B1 (en) 2007-11-26 2008-11-26 Bioactive and resorbable soybean-based biomaterials
ES08853269T ES2433207T3 (en) 2007-11-26 2008-11-26 Bioactive and reabsorbable soy-based biomaterials
JP2010535459A JP2011504406A (en) 2007-11-26 2008-11-26 Soy biomaterial that is bioactive and resorbable
US12/744,848 US20110027364A1 (en) 2007-11-26 2008-11-26 Bioactive and resorbable soybean-based biomaterials

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0723102.0A GB0723102D0 (en) 2007-11-26 2007-11-26 Bioactive and resorbable soy-based biomaterials
GB0723102.0 2007-11-26

Publications (2)

Publication Number Publication Date
WO2009068913A2 WO2009068913A2 (en) 2009-06-04
WO2009068913A3 true WO2009068913A3 (en) 2010-06-24

Family

ID=38926032

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2008/051117 WO2009068913A2 (en) 2007-11-26 2008-11-26 Bioactive and resorbable soybean-based biomaterials

Country Status (6)

Country Link
US (1) US20110027364A1 (en)
EP (1) EP2222347B1 (en)
JP (1) JP2011504406A (en)
ES (1) ES2433207T3 (en)
GB (1) GB0723102D0 (en)
WO (1) WO2009068913A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2968004B1 (en) * 2010-11-29 2013-06-28 Sojasun Technologies BIODEGRADABLE NATURAL FILMS BASED ON CO-PRODUCTS FROM INDUSTRIAL PROCESSES FOR SEED TREATMENT.
WO2012120516A1 (en) * 2011-03-09 2012-09-13 Ramot At Tel-Aviv University Ltd. Soy protein-based structures and uses thereof
CN102488210B (en) * 2011-12-27 2013-06-19 西南大学 Genistein hydrogel compound and its preparation method
US20180362957A1 (en) * 2017-06-14 2018-12-20 R. J. Reynolds Tobacco Company RuBisCO Protein-Based Films
CN107441550A (en) * 2017-07-18 2017-12-08 张家港祥成医用材料科技有限公司 A kind of production method of isoflavones aerogel dressing for wound repair
CN109602911B (en) * 2019-01-09 2020-11-10 厦门大学 Application of calcium sulfate whisker or composition thereof in preparation of skin penetration enhancer
EP3967731A1 (en) * 2020-09-09 2022-03-16 Xampla Limited Protein dispersions
CN115089767B (en) * 2022-05-25 2023-06-20 中山大学 Soybean wound repair material and preparation method and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010512A1 (en) * 1993-10-12 1995-04-20 Protein Technologies International, Inc. An aglucone isoflavone enriched vegetable protein whey, whey protein, and process for producing
WO2002010261A1 (en) * 2000-08-02 2002-02-07 Biomed Interfaces B.V. Soybean-based thermoplastics as biomaterials
US20050123662A1 (en) * 2002-03-14 2005-06-09 Satoshi Wanezaki Soybean saponin-containing material and process for producing the same
US20070054031A1 (en) * 2005-09-02 2007-03-08 Keshun Liu Methods of extracting, concentrating and fractionating proteins and other chemical components
US20070077305A1 (en) * 2005-10-03 2007-04-05 Le Tien C Biocompatible polymeric matrix and preparation thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2495706A (en) * 1947-10-29 1950-01-31 Voss Letta I De Vegetable gel
US4172828A (en) * 1977-09-30 1979-10-30 Anderson, Clayton & Co. Method for processing soy protein and composition of matter
US6306997B1 (en) * 1999-07-29 2001-10-23 Iowa State University Research Foundation, Inc. Soybean-based adhesive resins and composite products utilizing such adhesives
US20030148084A1 (en) * 2000-02-11 2003-08-07 Trocino Frank S. Vegetable protein adhesive compositions
US7465470B2 (en) * 2001-02-28 2008-12-16 Fuji Oil Company, Limited Process for producing a soybean protein usable in acidic foods
US6818246B2 (en) * 2001-04-09 2004-11-16 Solae, Llc Soy protein concentrate having high isoflavone content and process for its manufacture
WO2007103785A2 (en) * 2006-03-03 2007-09-13 Specialty Protein Producers, Inc. Plant-derived protein compositions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010512A1 (en) * 1993-10-12 1995-04-20 Protein Technologies International, Inc. An aglucone isoflavone enriched vegetable protein whey, whey protein, and process for producing
WO2002010261A1 (en) * 2000-08-02 2002-02-07 Biomed Interfaces B.V. Soybean-based thermoplastics as biomaterials
US20050123662A1 (en) * 2002-03-14 2005-06-09 Satoshi Wanezaki Soybean saponin-containing material and process for producing the same
US20070054031A1 (en) * 2005-09-02 2007-03-08 Keshun Liu Methods of extracting, concentrating and fractionating proteins and other chemical components
US20070077305A1 (en) * 2005-10-03 2007-04-05 Le Tien C Biocompatible polymeric matrix and preparation thereof

Also Published As

Publication number Publication date
EP2222347B1 (en) 2013-07-31
JP2011504406A (en) 2011-02-10
ES2433207T3 (en) 2013-12-09
WO2009068913A2 (en) 2009-06-04
EP2222347A2 (en) 2010-09-01
US20110027364A1 (en) 2011-02-03
GB0723102D0 (en) 2008-01-02

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