WO2009066225A1 - Method, system and computer program for visually representing contrast-enhanced angiographic images - Google Patents

Method, system and computer program for visually representing contrast-enhanced angiographic images Download PDF

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Publication number
WO2009066225A1
WO2009066225A1 PCT/IB2008/054804 IB2008054804W WO2009066225A1 WO 2009066225 A1 WO2009066225 A1 WO 2009066225A1 IB 2008054804 W IB2008054804 W IB 2008054804W WO 2009066225 A1 WO2009066225 A1 WO 2009066225A1
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WIPO (PCT)
Prior art keywords
color
wavelength
information
contrast
interest
Prior art date
Application number
PCT/IB2008/054804
Other languages
French (fr)
Inventor
Arianne Van Muiswinkel
Liesbeth Geerts-Ossevoort
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Koninklijke Philips Electronics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Koninklijke Philips Electronics N.V. filed Critical Koninklijke Philips Electronics N.V.
Publication of WO2009066225A1 publication Critical patent/WO2009066225A1/en

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    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/00—2D [Two Dimensional] image generation
    • G06T11/001—Texturing; Colouring; Generation of texture or colour
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2210/00—Indexing scheme for image generation or computer graphics
    • G06T2210/41—Medical

Definitions

  • the invention relates to a method for visually representing contrast-enhanced angiographic images from a patient's region of interest, which images embody temporal information concerning the contrast arrival time in respective parts of said region of interest, wherein for each of said parts the contrast arrival time is visualized by a color that is selected in dependence of said arrival time.
  • a drawback of this known method and system is that colors that are having a relatively short wavelength such as green, blue and violet are interpreted to be further away than colors with a relatively longer wavelength such as yellow, orange and red.
  • a method is proposed that is characterized in that a signal representative for a pre-selected parameter of the color that is selected in dependence of the arrival time of the contrast agent is adjusted to a value that depends on the color's wavelength.
  • the pre-selected parameter of the color is the color's brightness or lightness.
  • the said signal is adjusted so as to cause that the color's brightness of lightness is enhanced for colors having a shorter wavelength as compared to colors with a longer wavelength.
  • the visual depth perception of the pixels in an image can be made indifferent with respect to the colors of the respective pixels, i.e. the color's brightness or lightness is for each color adapted so as to display all colors with an essentially uniform depth perception.
  • the invention is also embodied in a system for visually representing contrast- enhanced angiographic images from a patient's region of interest.
  • a system may comprise a data-source such as a data-acquisition apparatus or the data may be supplied by a data carrier or another suitable system.
  • a display-apparatus may be connected or connectable to said data-source, wherein the display-apparatus comprises a color monitor and a driver for said color monitor for converting image-information provided by the data-source into visual display information for the color monitor.
  • this system is characterized in that the driver is embodied so as to adapt for each color to be displayed on the color monitor, a signal representative for a pre-selected parameter of color- information that is comprised in the visual display information, which adaptation depends on the wavelength of each such color.
  • the invention is embodied in a computer program for representing contrast-enhanced angiographic images from a patient's region of interest by converting said images into visual display information for a color monitor, wherein said visual display information comprises color information.
  • this computer program is characterized in that in use and for each color represented by said color information a pre-selected parameter of said color is adapted depending on said color's wavelength.
  • the invention also applies to a data-carrier that is provided with the just- mentioned computer program.
  • FIG. 1 shows schematically a system according to the invention
  • - Fig. 2 shows a graph representing the correction- factor of a pre-selected parameter of a displayed color depending on such color's wavelength.
  • a system 1 for visually representing a contrast-enhanced angiographic image or images from a patient's region of interest.
  • the images are for instance collected with a data-acquisition apparatus 2 such as an MR- or CT-apparatus.
  • the data-acquisition apparatus 2 is intermediately connected with a color monitor 4 which is part of a display apparatus 3.
  • the display apparatus 3 also comprises a driver 5 which provides image signals to the color monitor 4 depending on the image information from the data-acquisition apparatus 2.
  • the driver 5 converts image information that is collected with said data acquisition apparatus 2 into visual display information for the color monitor 4, and in accordance with the invention the driver 5 is embodied to adapt a signal representative for a pre-selected parameter of the color information for each color to be displayed on the color monitor 4, that is comprised in the visual display information that the driver 5 submits to the color monitor 4.
  • the driver 5 adapts said parameter depending on the wavelength of the color represented by the information to be transmitted to the color monitor 4.
  • Fig. 1 also shows that the display apparatus 3 of the system 1 may have a calibration facility 6.
  • the calibration facility accepts an input from the user to determine the level of adaptation of the signal for a given wavelength.
  • Fig. 2 represents schematically the manner of adaptation of the aforesaid pre- selected parameter of the color to a value that depends on the color's wavelength.
  • the X-axis of the graph shown in Fig. 2 represents the color's wavelengths, wherein the wavelengths at the left part of the graph correspond to longer wavelengths such as yellow, orange and red and the right-hand part of the figure corresponds to shorter wavelength colors such as green, blue and violet.
  • the Y-axis of the graph represents the level of adjustment of the signal for the various wavelengths.
  • the graph shown in Fig. 2 clearly illustrates that the pre-selected parameter of the color information is adjusted either proportionally (graph A) depending on the color's wavelength or exponentially (graph B) depending on the color's wavelength.
  • the pre-selected parameter to be used for the adjustment of the color information is selected to be the color's brightness or lightness.
  • the color's brightness or lightness is enhanced for colors having a shorter wavelength as compared to colors with a longer wavelength.
  • the level of adjustment is indicated on the Y-axis of the graph.

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

The invention relates to a method for visually representing contrast-enhanced angiographic images from a patient's region of interest, which images embody temporal information concerning the contrast arrival time in respective parts of said region of interest, wherein for each of said parts the contrast arrival time is visualized by a color that is selected in dependence of said arrival time, wherein a signal representative for a pre-selected parameter of the color is adjusted to a value that depends on the color's wavelength.

Description

Method, system and computer program for visually representing contrast-enhanced angiographic images
FIELD OF THE INVENTION
The invention relates to a method for visually representing contrast-enhanced angiographic images from a patient's region of interest, which images embody temporal information concerning the contrast arrival time in respective parts of said region of interest, wherein for each of said parts the contrast arrival time is visualized by a color that is selected in dependence of said arrival time.
BACKGROUND OF THE INVENTION
Such a method is known from the article "Color Intensity Projection of Digitally Subtracted Angiography for the Visualization of Brain Arteriovenous
Malformations", published in Neurosurgery, volume 60, no. 3, March 2007, pages 511-514 by Keith S. Cover, et al.
From this article it is known to combine the standard gray-scale images produced by digital subtraction angiography into a single composite color image that encodes the contrast arrival time at each point of the brain's circulatory system. In this known method the arrival time of contrast at each pixel is represented by the pixel's hue, brightness and saturation conveying the intensity and intensity variation, respectively, of the pixel over the digital subtraction angiography images. Thus, the images summarize all temporal information of a series of digital subtraction angiography images within a single composite image allowing for easier evaluation of such images. In this method the areas that are filled with contrast earliest are red, intermediate areas are yellow and areas that fill late are coded green or blue. This exactly follows the well-known rainbow-colors.
A drawback of this known method and system is that colors that are having a relatively short wavelength such as green, blue and violet are interpreted to be further away than colors with a relatively longer wavelength such as yellow, orange and red.
SUMMARY OF THE INVENTION It is an object of the invention to alleviate the interpretation of visual images that are derived from contrast-enhanced angiographic images such as magnetic resonance angiography and other types of data acquisition means in which contrast agents are applied.
For this purpose according to the invention a method, system and computer program is proposed in accordance with one or more of the appended claims.
In a first aspect of the invention a method is proposed that is characterized in that a signal representative for a pre-selected parameter of the color that is selected in dependence of the arrival time of the contrast agent is adjusted to a value that depends on the color's wavelength. Thus, it is possible to compensate for the sensitivity of the human eye for each color, making it easier to evaluate the resulting visual images carrying the information pertaining to the time of arrival of the contrast agent in the respective parts of the patient's region of interest.
It is found to be preferable that the pre-selected parameter of the color is the color's brightness or lightness. By increasing the brightness or lightness of colors that are relatively close to green, blue or violet it is possible to experience these colors in a way comparable to colors having a longer wavelength such as yellow, orange or red for which less or no brightness or lightness correction occurs.
Correspondingly it is preferable that the said signal is adjusted so as to cause that the color's brightness of lightness is enhanced for colors having a shorter wavelength as compared to colors with a longer wavelength. This allows that the visual depth perception of the pixels in an image can be made indifferent with respect to the colors of the respective pixels, i.e. the color's brightness or lightness is for each color adapted so as to display all colors with an essentially uniform depth perception.
It is possible that the adjustment of the color's brightness or lightness is done proportionally or even exponentially depending on the color's wavelength.
It is further possible to have the user calibrate the adjustment of the color's brightness or lightness, preferably by using an appropriate facility for this purpose that forms part of the system to be discussed hereinafter.
The invention is also embodied in a system for visually representing contrast- enhanced angiographic images from a patient's region of interest. Such a system may comprise a data-source such as a data-acquisition apparatus or the data may be supplied by a data carrier or another suitable system. A display-apparatus may be connected or connectable to said data-source, wherein the display-apparatus comprises a color monitor and a driver for said color monitor for converting image-information provided by the data-source into visual display information for the color monitor.
According to the invention this system is characterized in that the driver is embodied so as to adapt for each color to be displayed on the color monitor, a signal representative for a pre-selected parameter of color- information that is comprised in the visual display information, which adaptation depends on the wavelength of each such color.
Also the invention is embodied in a computer program for representing contrast-enhanced angiographic images from a patient's region of interest by converting said images into visual display information for a color monitor, wherein said visual display information comprises color information.
According to the invention this computer program is characterized in that in use and for each color represented by said color information a pre-selected parameter of said color is adapted depending on said color's wavelength.
The invention also applies to a data-carrier that is provided with the just- mentioned computer program.
BRIEF DESCRIPTION OF THE DRAWINGS
The invention will hereinafter be further elucidated with reference to an exemplary embodiment of the system of the invention and with reference to the drawing. In the drawings:
- Fig. 1 shows schematically a system according to the invention, and
- Fig. 2 shows a graph representing the correction- factor of a pre-selected parameter of a displayed color depending on such color's wavelength.
DETAILED DESCRIPTION OF EMBODIMENTS
Referring first to Fig. 1 a system 1 is shown for visually representing a contrast-enhanced angiographic image or images from a patient's region of interest.
The images are for instance collected with a data-acquisition apparatus 2 such as an MR- or CT-apparatus. The data-acquisition apparatus 2 is intermediately connected with a color monitor 4 which is part of a display apparatus 3. The display apparatus 3 also comprises a driver 5 which provides image signals to the color monitor 4 depending on the image information from the data-acquisition apparatus 2. To this end the driver 5 converts image information that is collected with said data acquisition apparatus 2 into visual display information for the color monitor 4, and in accordance with the invention the driver 5 is embodied to adapt a signal representative for a pre-selected parameter of the color information for each color to be displayed on the color monitor 4, that is comprised in the visual display information that the driver 5 submits to the color monitor 4. In accordance with the invention the driver 5 adapts said parameter depending on the wavelength of the color represented by the information to be transmitted to the color monitor 4.
Fig. 1 also shows that the display apparatus 3 of the system 1 may have a calibration facility 6. The calibration facility accepts an input from the user to determine the level of adaptation of the signal for a given wavelength.
Fig. 2 represents schematically the manner of adaptation of the aforesaid pre- selected parameter of the color to a value that depends on the color's wavelength. To this end the X-axis of the graph shown in Fig. 2 represents the color's wavelengths, wherein the wavelengths at the left part of the graph correspond to longer wavelengths such as yellow, orange and red and the right-hand part of the figure corresponds to shorter wavelength colors such as green, blue and violet. The Y-axis of the graph represents the level of adjustment of the signal for the various wavelengths.
The graph shown in Fig. 2 clearly illustrates that the pre-selected parameter of the color information is adjusted either proportionally (graph A) depending on the color's wavelength or exponentially (graph B) depending on the color's wavelength.
It is preferred that the pre-selected parameter to be used for the adjustment of the color information is selected to be the color's brightness or lightness. Thus, the color's brightness or lightness is enhanced for colors having a shorter wavelength as compared to colors with a longer wavelength. The level of adjustment is indicated on the Y-axis of the graph.

Claims

CLAIMS:
1. Method for visually representing contrast-enhanced angiographic images from a patient's region of interest, which images embody temporal information concerning the contrast arrival time in respective parts of said region of interest, wherein for each of said parts the contrast arrival time is visualized by a color that is selected in dependence of said arrival time, characterized in that a signal representative for a pre-selected parameter of the color is adjusted to a value that depends on the color's wavelength.
2. Method according to claim 1, characterized in that the pre-selected parameter of the color is the color's brightness or lightness.
3. Method according to claim 1 or 2, characterized in that the said signal is adjusted so as to cause that the color's brightness of lightness is enhanced for colors having a shorter wavelength as compared to colors with a longer wavelength.
4. Method according to claim 3, characterized in that the said signal is adjusted so as to cause that the color's brightness or lightness is for each color adapted so as to display all colors with an essentially uniform depth perception.
5. Method according to claim 3, characterized in that the said signal is adjusted so as to cause that the color's brightness of lightness is enhanced proportionally or exponentially depending on the color's wavelength.
6. Method for visually representing contrast-enhanced angiographic images from a patient's region of interest characterized in that a signal representative for a pre-selected parameter of the color is adjusted so as to compensate the sensitivity of the human eye for said color.
7. System (1) for visually representing contrast-enhanced angiographic images from a patient's region of interest, comprising a data source selected from the group comprising a data-acquisition apparatus (2) and a data carrier, and a display-apparatus (3) connected or connectable to said data-source (2), wherein the display-apparatus (3) comprises a color monitor (4) and a driver (5) for said color monitor (4) for converting image- information provided by the data-source (2) into visual display information for the color monitor (4), characterized in that the driver (5) is embodied so as to adapt for each color to be displayed on the color monitor (4), a signal representative for a pre-selected parameter of color-information that is comprised in the visual display information, which adaptation depends on the wavelength of each such color.
8. System (1) according to claim 7, wherein same comprises a calibration facility
(6) for said pre-selected parameter that depends on user-input to the system.
9. Computer program for representing contrast-enhanced angiographic images from a patient's region of interest by converting said images into visual display information for a color monitor, wherein said visual display information comprises color information, characterized in that in use and for each color represented by said color information a preselected parameter of said color is adapted depending on said color's wavelength.
10. Data-carrier provided with the computer program of claim 9.
PCT/IB2008/054804 2007-11-23 2008-11-17 Method, system and computer program for visually representing contrast-enhanced angiographic images WO2009066225A1 (en)

Applications Claiming Priority (2)

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EP07121437.3 2007-11-23
EP07121437 2007-11-23

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6865287B1 (en) * 1999-09-09 2005-03-08 Heimann Systems Gmbh Method for adjusting color in an image

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6865287B1 (en) * 1999-09-09 2005-03-08 Heimann Systems Gmbh Method for adjusting color in an image

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
COVER KEITH S ET AL: "Color intensity projection of digitally subtracted angiography for the visualization of brain arteriovenous malformations", NEUROSURGERY, MCGRAW-HILL, NEW YORK, NY, US, vol. 60, no. 3, 1 March 2007 (2007-03-01), pages 511 - 514, XP009112333 *
KNUTSSON H ET AL: "Spatio-temporal filtering of digital angiography image data.", COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 1998 AUG-SEP, vol. 57, no. 1-2, August 1998 (1998-08-01), pages 115 - 123, XP002515603, ISSN: 0169-2607 *
PENNY RHEINGANS AND CHRIS LANDRETH: "Perceptual Principles for Effective Visualizations", PERCEPTUAL ISSUES IN VISUALIZATION, 1995, Springer Verlag, pages 59 - 74, XP002515604 *
SAMUEL SILVA ET AL: "There is More to Color Scales than Meets the Eye: A Review on the Use of Color in Visualization", INFORMATION VISUALIZATION, 2007. IV '07. 11TH INTERNATIONAL CONFERENCE, IEEE, PI, 1 July 2007 (2007-07-01), pages 943 - 950, XP031115787, ISBN: 978-0-7695-2900-4 *

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