WO2009062914A3 - Blood pressure lowering combination comprising ipp and/or vpp - Google Patents

Blood pressure lowering combination comprising ipp and/or vpp Download PDF

Info

Publication number
WO2009062914A3
WO2009062914A3 PCT/EP2008/065242 EP2008065242W WO2009062914A3 WO 2009062914 A3 WO2009062914 A3 WO 2009062914A3 EP 2008065242 W EP2008065242 W EP 2008065242W WO 2009062914 A3 WO2009062914 A3 WO 2009062914A3
Authority
WO
WIPO (PCT)
Prior art keywords
ipp
vpp
blood pressure
pressure lowering
lowering combination
Prior art date
Application number
PCT/EP2008/065242
Other languages
French (fr)
Other versions
WO2009062914A2 (en
Inventor
Van Der Lucas Cyril Gerard Heyden
Joris Kloek
Original Assignee
Dsm Ip Assets B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets B.V. filed Critical Dsm Ip Assets B.V.
Priority to JP2010533552A priority Critical patent/JP2011504464A/en
Priority to EP08848815A priority patent/EP2209483A2/en
Priority to CN2008801247324A priority patent/CN101909645A/en
Publication of WO2009062914A2 publication Critical patent/WO2009062914A2/en
Publication of WO2009062914A3 publication Critical patent/WO2009062914A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

The present invention provides a composition comprising a peptide which is IPP and/or VPP; and at least one compound which can be extracted or purified from a natural source, this compound is preferably selected from the group consisting of CoQ10, grape seed extract, resveratrol, EGCG, Vitamin D, Pufa, GABA, Lycopene, Hawthorne, hydroxytyrosol or is preferably selected on anti-oxidative action of the polyphenols present in grape seed extract or isolate.
PCT/EP2008/065242 2007-11-14 2008-11-10 Novel blood pressure lowering composition WO2009062914A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2010533552A JP2011504464A (en) 2007-11-14 2008-11-10 Novel blood pressure lowering composition
EP08848815A EP2209483A2 (en) 2007-11-14 2008-11-10 Blood pressure lowering combination comprising ipp and/or vpp
CN2008801247324A CN101909645A (en) 2007-11-14 2008-11-10 Comprise the blood pressure lowering combination of IPP and/or VPP

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07120625 2007-11-14
EP07120625.4 2007-11-14

Publications (2)

Publication Number Publication Date
WO2009062914A2 WO2009062914A2 (en) 2009-05-22
WO2009062914A3 true WO2009062914A3 (en) 2009-11-05

Family

ID=39272173

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/065242 WO2009062914A2 (en) 2007-11-14 2008-11-10 Novel blood pressure lowering composition

Country Status (4)

Country Link
EP (1) EP2209483A2 (en)
JP (1) JP2011504464A (en)
CN (1) CN101909645A (en)
WO (1) WO2009062914A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103127045B (en) * 2013-02-05 2014-10-29 新疆优康来生物科技开发有限公司 Composition containing gamma-aminobutyric acid and lycopene and preparation method thereof
CN107375897A (en) * 2017-08-15 2017-11-24 普维食品发展（上海）有限公司 A kind of composition of aided blood pressure-lowering and application thereof
CN109380728B (en) * 2018-10-17 2022-03-22 汤臣倍健股份有限公司 Composition and health food with auxiliary blood pressure lowering effect
CN111919963B (en) * 2020-07-10 2021-06-01 青岛农业大学 Method for preparing hydrolysate rich in IPP and VPP from wheat gluten protein by enzyme method
CN114010773A (en) * 2021-10-26 2022-02-08 江苏协合转化医学研究院有限公司 Composition formula for reducing blood pressure without side effect and preparation process and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1018341A1 (en) * 1997-09-26 2000-07-12 Calpis Co., Ltd. Antistress agents and functional foods
JP2002241305A (en) * 2001-02-14 2002-08-28 Yakult Honsha Co Ltd Prophylactic/therapeutic agent for hypertension
WO2005011660A1 (en) * 2003-07-29 2005-02-10 Abbott Laboratories Use of vitamin d to down regulate the renin-angiotensin-aldosterone system
US20050143356A1 (en) * 2003-12-08 2005-06-30 Vanderbilt University Selective inhibition of cyclooxygenase 1 in the treatment of diabetic nephropathy
WO2007079977A2 (en) * 2006-01-16 2007-07-19 Dsm Ip Assets B.V. Nutraceutical compositions comprising tripeptides

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1018341A1 (en) * 1997-09-26 2000-07-12 Calpis Co., Ltd. Antistress agents and functional foods
JP2002241305A (en) * 2001-02-14 2002-08-28 Yakult Honsha Co Ltd Prophylactic/therapeutic agent for hypertension
WO2005011660A1 (en) * 2003-07-29 2005-02-10 Abbott Laboratories Use of vitamin d to down regulate the renin-angiotensin-aldosterone system
US20050143356A1 (en) * 2003-12-08 2005-06-30 Vanderbilt University Selective inhibition of cyclooxygenase 1 in the treatment of diabetic nephropathy
WO2007079977A2 (en) * 2006-01-16 2007-07-19 Dsm Ip Assets B.V. Nutraceutical compositions comprising tripeptides

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; March 2005 (2005-03-01), WEISINGER RICHARD STUART ET AL: "Dietary omega-3 polyunsaturated fatty acids reduce blood pressure of hypertensive TGR (mRen2)27 transgenic rats", XP002477073 *
DATABASE EMBASE ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; 2004, HABS M: "Prospective, comparative cohort studies and their contribution to the benefit assessments of therapeutic options: Heart failure treatment with and without hawthorn special extract WS(R) 1442", XP002477074 *
DATABASE WPI Week 200311, Derwent World Patents Index; AN 2003-114676, XP002477075 *
FASEB JOURNAL, vol. 19, no. 4, Suppl. S, Part 1, March 2005 (2005-03-01), EXPERIMENTAL BIOLOGY 2005 MEETING/35TH INTERNATIONAL CONGRESS OF PHYSIOLOGICAL SCIENCES; SAN DIEGO, CA, USA; MARCH 31 -APRIL 06, 2005, pages A968 *
FORSCHENDE KOMPLEMENTARMEDIZIN UND KLASSISCHE NATURHEILKUNDE 2004 CH, vol. 11, no. SUPPL. 1, 2004, pages 36 - 39 *
HARA Y ET AL: "ANGIOTENSIN I CONVERTING ENZYME INHIBITING ACTIVITY OF TEA COMPONENTS", BIOSIS, 1987, XP002311587 *
KWON YOUNG-IN I ET AL: "Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension.", ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION 2006, vol. 15, no. 1, 2006, pages 107 - 118, XP009080781, ISSN: 0964-7058 *

Also Published As

Publication number Publication date
EP2209483A2 (en) 2010-07-28
WO2009062914A2 (en) 2009-05-22
CN101909645A (en) 2010-12-08
JP2011504464A (en) 2011-02-10

Similar Documents

Publication Publication Date Title
CY1121136T1 (en) HERBAL EXTRACTS CONTAINING CANNABINOIDS AS NEUROPROSPERATIVE FACTORS
UA108852C2 (en) Application of one or a combination of herbal cannabinoids for epilepsy treatment
AR059545A1 (en) VERBACOSIDE AND LUTEOLINE COMBINATION
WO2008006581A3 (en) Compositions and use thereof for the treatment, co-treatment or prevention of imflammatory disorders
WO2009012871A3 (en) Uv filter capsule
MX2009007088A (en) Composition containing a quinoa grain extract for dematological use.
WO2008085828A3 (en) Peptide modulators of angiogenesis and use thereof
WO2009062914A3 (en) Blood pressure lowering combination comprising ipp and/or vpp
WO2010069532A8 (en) Antibodies against human angiopoietin 2
WO2009035818A8 (en) Compounds that modulate intracellular calcium
WO2009076454A3 (en) Compounds that modulate intracellular calcium
CL2008000691A1 (en) COMPOUNDS DERIVED FROM DIHIDRO AND TETRAHIDRO OXAZOLOPIRIMIDINONAS REPLACED; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS; AND ITS USE FOR THE TREATMENT OF CHICHOPHRENIA, EPILEPSY, BETWEEN OTHER DISEASES.
CR11731A (en) COMPOSITIONS AND PROCEDURES FOR PREPARATION AND USE
WO2007117556A3 (en) Pharmaceutical compositions and uses thereof
WO2011073437A3 (en) Bacteriocin- and prebiotic-based cosmetic or dermatological compositions
WO2007042272A3 (en) Use of a nutraceutical composition comprising resveratrol for the treatment of age-related diseases
BRPI0716985A2 (en) NUTRITIONAL COMPOSITION, USE OF THE SAME, AND NUTRITIONAL SUPPLEMENT FOR THE TREATMENT OF PATIENTS SUFFERING FROM FOOD ALLERGIES
DOP2009000213A (en) STABILIZATION OF VITAMINS B12
GT200800068A (en) TYPE OF BROCOLI CONTAINING INFLORESCENCE WITH SEPARATE FLOSCULES.
WO2006045874A3 (en) Use of the slug gene or the replication, transcription or expression products thereof in the identification, diagnosis, prevention or treatment of the spread of cancer and/or the development of metastasis
WO2007148022A3 (en) Cosmetic product sterilization
WO2010068815A3 (en) Compositions and methods for treating cellular proliferative disorders
WO2010046061A3 (en) Cosmetic and/or pharmaceutical formulations
WO2010011997A3 (en) Compositions comprising docynia delavajy extract and/or elaeagnus lancelotus extract
WO2010147814A3 (en) Combinations of herb extracts having synergistic antioxidant effect, and methods relating thereto

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880124732.4

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08848815

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2008848815

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2010533552

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE