WO2009026348A3 - Antifungal agents from a streptomycete - Google Patents

Antifungal agents from a streptomycete Download PDF

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Publication number
WO2009026348A3
WO2009026348A3 PCT/US2008/073687 US2008073687W WO2009026348A3 WO 2009026348 A3 WO2009026348 A3 WO 2009026348A3 US 2008073687 W US2008073687 W US 2008073687W WO 2009026348 A3 WO2009026348 A3 WO 2009026348A3
Authority
WO
WIPO (PCT)
Prior art keywords
streptomycete
antifungal agents
potent
compound
antifungal compound
Prior art date
Application number
PCT/US2008/073687
Other languages
French (fr)
Other versions
WO2009026348A2 (en
Inventor
Dong-Chan Oh
Jon C Clardy
Jarrod Scott
Cameron Currie
Original Assignee
Harvard College
Wisconsin Alumni Res Found
Dong-Chan Oh
Jon C Clardy
Jarrod Scott
Cameron Currie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Wisconsin Alumni Res Found, Dong-Chan Oh, Jon C Clardy, Jarrod Scott, Cameron Currie filed Critical Harvard College
Publication of WO2009026348A2 publication Critical patent/WO2009026348A2/en
Publication of WO2009026348A3 publication Critical patent/WO2009026348A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/02—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 2
    • C07D317/04—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 2 not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A Streptomycete bacteria associated with the Southern Pine Beetle (SPB) has been found to synthesize a potent antifungal compound. The spectrum of activity of the isolated antifungal compound is similar to that of amphotericin, and the compound is approximately three-times more potent on a weight basis.
PCT/US2008/073687 2007-08-20 2008-08-20 Antifungal agents from a streptomycete WO2009026348A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96558307P 2007-08-20 2007-08-20
US60/965,583 2007-08-20

Publications (2)

Publication Number Publication Date
WO2009026348A2 WO2009026348A2 (en) 2009-02-26
WO2009026348A3 true WO2009026348A3 (en) 2009-04-16

Family

ID=40378968

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/073687 WO2009026348A2 (en) 2007-08-20 2008-08-20 Antifungal agents from a streptomycete

Country Status (1)

Country Link
WO (1) WO2009026348A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3094368A1 (en) * 2019-03-27 2020-10-02 Universite Paris-Sud Process for the preparation of 1,2-endoperoxide compounds
FR3094369A1 (en) * 2019-03-27 2020-10-02 Universite Paris-Sud New therapeutic application of 1,2-dioxolane-3,5-disubtituted compounds and their manufacturing process
CN113975263B (en) * 2021-10-20 2023-06-09 河南希百康健康产业有限公司 Composition for inhibiting fungi and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987004708A1 (en) * 1986-02-04 1987-08-13 Harbor Branch Oceanographic Institution, Inc. Novel dioxolane compositions and their method of use
WO1997021699A1 (en) * 1995-12-09 1997-06-19 Zeneca Limited Process for making 1,2-dioxolanes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987004708A1 (en) * 1986-02-04 1987-08-13 Harbor Branch Oceanographic Institution, Inc. Novel dioxolane compositions and their method of use
WO1997021699A1 (en) * 1995-12-09 1997-06-19 Zeneca Limited Process for making 1,2-dioxolanes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ASFIA QURESHI ET AL.: "New Cyclic Peroxides from the Philippine Sponge Plaknastrella sp.", J.NAT. PROD., vol. 61, no. 12, 1998, pages 1539 - 1542 *

Also Published As

Publication number Publication date
WO2009026348A2 (en) 2009-02-26

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