WO2009025315A1 - Oral preparation for improvement of bioavailability of curcumin - Google Patents

Oral preparation for improvement of bioavailability of curcumin Download PDF

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Publication number
WO2009025315A1
WO2009025315A1 PCT/JP2008/064886 JP2008064886W WO2009025315A1 WO 2009025315 A1 WO2009025315 A1 WO 2009025315A1 JP 2008064886 W JP2008064886 W JP 2008064886W WO 2009025315 A1 WO2009025315 A1 WO 2009025315A1
Authority
WO
WIPO (PCT)
Prior art keywords
curcumin
bioavailability
oral preparation
improvement
disclosed
Prior art date
Application number
PCT/JP2008/064886
Other languages
French (fr)
Japanese (ja)
Inventor
Yasushi Sakai
Erika Kagami
Koji Morishita
Original Assignee
Kyowa Hakko Bio Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Bio Co., Ltd. filed Critical Kyowa Hakko Bio Co., Ltd.
Publication of WO2009025315A1 publication Critical patent/WO2009025315A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Disclosed is a composition for increasing the amount of tetrahydrocurcumin, which is believed to be useful for the maintenance of good health or the amelioration of a disease condition, in a living body efficiently through oral intake. Specifically disclosed is an oral preparation for improving the bioavailability of a curcumin, which comprises a curcumin and a magnesium salt as active ingredients.
PCT/JP2008/064886 2007-08-21 2008-08-21 Oral preparation for improvement of bioavailability of curcumin WO2009025315A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-214303 2007-08-21
JP2007214303 2007-08-21

Publications (1)

Publication Number Publication Date
WO2009025315A1 true WO2009025315A1 (en) 2009-02-26

Family

ID=40378214

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/064886 WO2009025315A1 (en) 2007-08-21 2008-08-21 Oral preparation for improvement of bioavailability of curcumin

Country Status (1)

Country Link
WO (1) WO2009025315A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20111259A1 (en) * 2011-07-06 2013-01-07 Eye Tech Srl QUICK-RELEASE ORO-SOLUBLE COMPOSITION CONTAINING CURCUMINE DERIVATIVES
WO2018077958A1 (en) 2016-10-27 2018-05-03 Unilever N.V. A personal care composition comprising curcuminoids
CN110261496A (en) * 2019-04-17 2019-09-20 四川省中医药科学院 A kind of detection method of content of tetrahydro curcumin

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003002827A (en) * 2001-06-20 2003-01-08 Kyowa Hakko Kogyo Co Ltd Preventing or ameliorating agent for preventing or ameliorating increase in blood neutral fat
JP2007063138A (en) * 2005-08-29 2007-03-15 Daicho Kikaku:Kk Therapeutic agent for irritable colitis, therapeutic agent for ulcerative colitis, therapeutic agent for crohn's disease, therapeutic agent for regional ileitis and therapeutic agent for sterility
CN1935006A (en) * 2006-09-28 2007-03-28 王增礼 Konjaku flour suitable for diabetes
CN1969815A (en) * 2006-11-29 2007-05-30 浙江工业大学 Sustained release agent of curcumin and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003002827A (en) * 2001-06-20 2003-01-08 Kyowa Hakko Kogyo Co Ltd Preventing or ameliorating agent for preventing or ameliorating increase in blood neutral fat
JP2007063138A (en) * 2005-08-29 2007-03-15 Daicho Kikaku:Kk Therapeutic agent for irritable colitis, therapeutic agent for ulcerative colitis, therapeutic agent for crohn's disease, therapeutic agent for regional ileitis and therapeutic agent for sterility
CN1935006A (en) * 2006-09-28 2007-03-28 王增礼 Konjaku flour suitable for diabetes
CN1969815A (en) * 2006-11-29 2007-05-30 浙江工业大学 Sustained release agent of curcumin and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20111259A1 (en) * 2011-07-06 2013-01-07 Eye Tech Srl QUICK-RELEASE ORO-SOLUBLE COMPOSITION CONTAINING CURCUMINE DERIVATIVES
WO2018077958A1 (en) 2016-10-27 2018-05-03 Unilever N.V. A personal care composition comprising curcuminoids
CN110261496A (en) * 2019-04-17 2019-09-20 四川省中医药科学院 A kind of detection method of content of tetrahydro curcumin
CN110261496B (en) * 2019-04-17 2022-04-05 四川省中医药科学院 Method for detecting content of tetrahydrocurcumin

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