WO2009022893A8 - Composición farmacéutica que comprende la combinación de un agente antimicrobiano y un agente inhibidor selectivo de la enzima encefalinasa, indicada para el control y tratamiento de la diarrea aguda de origen bacteriano - Google Patents

Composición farmacéutica que comprende la combinación de un agente antimicrobiano y un agente inhibidor selectivo de la enzima encefalinasa, indicada para el control y tratamiento de la diarrea aguda de origen bacteriano Download PDF

Info

Publication number
WO2009022893A8
WO2009022893A8 PCT/MX2008/000100 MX2008000100W WO2009022893A8 WO 2009022893 A8 WO2009022893 A8 WO 2009022893A8 MX 2008000100 W MX2008000100 W MX 2008000100W WO 2009022893 A8 WO2009022893 A8 WO 2009022893A8
Authority
WO
WIPO (PCT)
Prior art keywords
selective
pharmaceutical composition
antimicrobial agent
control
enzyme inhibitor
Prior art date
Application number
PCT/MX2008/000100
Other languages
English (en)
French (fr)
Other versions
WO2009022893A1 (es
Inventor
María Elena GARCÍA ARMENTA
Josefina Santos Murillo
Víctor Guillermo ALVAREZ OCHOA
Original Assignee
ESPINOSA ABDALA, Leopoldo de Jesús
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ESPINOSA ABDALA, Leopoldo de Jesús filed Critical ESPINOSA ABDALA, Leopoldo de Jesús
Priority to BRPI0813087-6A2A priority Critical patent/BRPI0813087A2/pt
Priority to EP08793783A priority patent/EP2179733A4/en
Priority to ARP080103245A priority patent/AR067700A1/es
Publication of WO2009022893A1 publication Critical patent/WO2009022893A1/es
Publication of WO2009022893A8 publication Critical patent/WO2009022893A8/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una composición farmacéutica compuesta por la combinación sinérgica de un agente antimicrobiano, conocido como: Ciprof loxacino y un agente inhibidor selectivo de la enzima encefalinasa, tal como: Racecadotrilo, además de excipientes farmacéuticamente aceptables, mismos que se encuentran formulados en una sola unidad de dosis para ser administrada por vía oral, utilizada para el control y tratamiento de la diarrea aguda bacteriana, la cual proporciona un mayor efecto terapéutico, una mayor rapidez de acción en menor tiempo y la reducción del riesgo de que se presenten complicaciones graves.
PCT/MX2008/000100 2007-07-27 2008-07-25 Composición farmacéutica que comprende la combinación de un agente antimicrobiano y un agente inhibidor selectivo de la enzima encefalinasa, indicada para el control y tratamiento de la diarrea aguda de origen bacteriano WO2009022893A1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
BRPI0813087-6A2A BRPI0813087A2 (pt) 2007-07-27 2008-07-25 Composição farmacêutica compreendendo a combinação de um agente antimicrobiano e um agente inibidor seletivo da enzima encefalinasa, indicada para o controle e tratamento da diarréia aguda de origem bacteriana.
EP08793783A EP2179733A4 (en) 2007-07-27 2008-07-25 A PHARMACEUTICAL COMPOSITION COMPRISING AN ANTIMICROBIAL ACTIVE SUBSTANCE AND A SELECTIVE ENKEPHALINASE CYCLIST FOR USE AS THE CONTROL AND TREATMENT OF ACUTE BACTERIAL INHALATION
ARP080103245A AR067700A1 (es) 2007-07-27 2008-07-25 Composicion farmaceutica que comprende la combinacin de un agente antimicrobiano y un agente inhibidor selectivo de la enzima encefalinasa indicada para el contol y tratamiento de la diarrea aguda de origen bacteriano

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MXMX/A/2007/009121 2007-07-27
MX2007009121A MX2007009121A (es) 2007-07-27 2007-07-27 Composicion farmaceutica que comprende la combinacion de un agente antimicrobiano y un agente inhibidor selectivo de la enzima encefalinasa, indicada para el control y tratamiento de la diarrea aguda de origen bacteriano.

Publications (2)

Publication Number Publication Date
WO2009022893A1 WO2009022893A1 (es) 2009-02-19
WO2009022893A8 true WO2009022893A8 (es) 2009-09-11

Family

ID=40350867

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/MX2008/000100 WO2009022893A1 (es) 2007-07-27 2008-07-25 Composición farmacéutica que comprende la combinación de un agente antimicrobiano y un agente inhibidor selectivo de la enzima encefalinasa, indicada para el control y tratamiento de la diarrea aguda de origen bacteriano

Country Status (7)

Country Link
EP (1) EP2179733A4 (es)
AR (1) AR067700A1 (es)
CO (1) CO6260072A2 (es)
EC (1) ECSP109996A (es)
MX (1) MX2007009121A (es)
PE (1) PE20090507A1 (es)
WO (1) WO2009022893A1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015490D0 (en) * 2000-06-23 2000-08-16 Smithkline Beecham Lab Novel formulations
US20030143293A1 (en) * 2002-01-31 2003-07-31 Sergei Shushunov Compositions and methods for treating diarrhea

Also Published As

Publication number Publication date
EP2179733A1 (en) 2010-04-28
PE20090507A1 (es) 2009-05-20
AR067700A1 (es) 2009-10-21
EP2179733A4 (en) 2012-08-15
CO6260072A2 (es) 2011-03-22
ECSP109996A (es) 2010-03-31
WO2009022893A1 (es) 2009-02-19
MX2007009121A (es) 2009-02-18

Similar Documents

Publication Publication Date Title
WO2008022256A3 (en) Methods and compositions for preventing or treating age-related diseases
WO2008157537A3 (en) Compositions and methods of use for treating or preventing lipid related disorders
ZA200807879B (en) Use of bifidobacterium longum for the prevention and treatment of inflammation
NO20090887L (no) Fremgangsmate for behandling og forebygging av mukositt
GEP20156281B (en) Orally administered corticosteroid compositions
WO2007058990A3 (en) Therapy using cytokine inhibitors
WO2007062093A3 (en) Combination therapy for the treatment of cancer comprising a metalloprotease inhibitor
WO2007106537A3 (en) Aminoquinolones as gsk-3 inhibitors
WO2009074794A3 (en) Anti-inflammatory compositions and combinations
WO2010116385A3 (en) Pharmaceutical compositions for alleviating unpleasant taste
WO2007121088A3 (en) Combinations of therapeutic agents for treating cancer
WO2008008474A3 (en) Compositions and methods for the treatment of chronic pain conditions
JP2012502047A5 (es)
WO2007131070A3 (en) Compositions, dosage forms and methods of treating emesis
WO2008012796A3 (en) Pharmaceutical compositions comprising ccl2 and use of same for the treatment of inflammation
WO2008070010A3 (en) Hydroxylamine derivatives for the treatment of stroke
WO2009041798A8 (es) Composiciones farmacéuticas que comprenden la combinación de un agente antiinflamatorio no esteroideo y un agente inhibidor de la xantino oxidasa útiles para el control y tratamiento de la gota, artritis gotosa y enfermedades relacionadas.
BR112012006149A2 (pt) composição farmacêutica.
WO2014119985A3 (es) Composición farmacéutica con un inhibidor selectivo de la enzima fosfodiesterasa en forma de gel oral
WO2009022893A8 (es) Composición farmacéutica que comprende la combinación de un agente antimicrobiano y un agente inhibidor selectivo de la enzima encefalinasa, indicada para el control y tratamiento de la diarrea aguda de origen bacteriano
WO2008001113A3 (en) Use of wnt5a for inhibiting scarring
WO2007136615A3 (en) Combination cancer therapy
WO2007138233A3 (fr) Utilisation du zatosetron pour le traitement de la rosacee
WO2008100653A3 (en) Copper lowering treatment of cardiac disease
WO2007084383A3 (en) Method and composition for the treatment of parkinson's disease

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08793783

Country of ref document: EP

Kind code of ref document: A1

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 10015886

Country of ref document: CO

WWE Wipo information: entry into national phase

Ref document number: 2008793783

Country of ref document: EP

ENP Entry into the national phase

Ref document number: PI0813087

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20100127