WO2009019673A3 - Ampoule de mélange multichambre - Google Patents

Ampoule de mélange multichambre Download PDF

Info

Publication number
WO2009019673A3
WO2009019673A3 PCT/IL2007/000987 IL2007000987W WO2009019673A3 WO 2009019673 A3 WO2009019673 A3 WO 2009019673A3 IL 2007000987 W IL2007000987 W IL 2007000987W WO 2009019673 A3 WO2009019673 A3 WO 2009019673A3
Authority
WO
WIPO (PCT)
Prior art keywords
ampoule
mixture
components
housing
proximal
Prior art date
Application number
PCT/IL2007/000987
Other languages
English (en)
Other versions
WO2009019673A2 (fr
Inventor
Shlomo Haimi
Yehezkel Menashe
Original Assignee
Shlomo Haimi
Yehezkel Menashe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shlomo Haimi, Yehezkel Menashe filed Critical Shlomo Haimi
Priority to PCT/IL2007/000987 priority Critical patent/WO2009019673A2/fr
Publication of WO2009019673A2 publication Critical patent/WO2009019673A2/fr
Publication of WO2009019673A3 publication Critical patent/WO2009019673A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/288—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne une ampoule multicompartiment pour le stockage des composants séparés d'un mélange de composants multiples puis leur mélange dans une même ampoule. Le logement d'ampoule comporte une extrémité d'injection proximale. L'extrémité distale du logement d'ampoule est fermée par une douille terminale comportant un trou traversant axial. Une partie d'un élément plongeur mobile dans le sens axial traverse le trou traversant axial, s'étend dans le volume intérieur et est fixée de manière stationnaire à un élément piston mobile dans le sens axial, qui se déploie de manière coulissante dans le logement d'ampoule afin de diviser hermétiquement le volume intérieur en au moins une première et une seconde région de stockage qui sont préremplies avec les composants séparés qui seront mélangés ensemble juste avant leur utilisation. Le déplacement axial de l'élément plongeur, et ainsi de l'élément piston, dans une première direction, déverse un premier composant du mélange de la région de stockage distale à la région de stockage proximale, à travers une configuration d'écoulement à sens unique. Une fois les deux composants réunis dans une même région de stockage, ils peuvent être efficacement mélangés ensemble. Une fois les composants mélangés, l'injection du mélange peut être effectuée selon divers procédés. Le mélange peut être injecté comme s'il provenait d'une ampoule standard, en insérant l'aiguille d'une seringue à travers la membrane hermétique, et en extrayant la quantité prescrite de mélange. En variante, l'ampoule peut être insérée dans un dispositif d'injection, tel un stylet d'injection par exemple, comme pour une ampoule standard. Les caractéristiques supplémentaires d'une canule d'aiguille configurée pour être fixée directement à l'extrémité d'injection proximale du logement d'ampoule, et les graduations sur la tige du plongeur indiquant le volume injecté, combinées avec l'ampoule de base, constituent un mode de réalisation permettant de stocker les composants séparés du mélange avant utilisation, permettent de mélanger les composants ensemble dans la même ampoule, et peuvent être utilisés sous forme de seringue pour injecter le mélange directement dans le patient.
PCT/IL2007/000987 2007-08-07 2007-08-07 Ampoule de mélange multichambre WO2009019673A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/IL2007/000987 WO2009019673A2 (fr) 2007-08-07 2007-08-07 Ampoule de mélange multichambre

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IL2007/000987 WO2009019673A2 (fr) 2007-08-07 2007-08-07 Ampoule de mélange multichambre

Publications (2)

Publication Number Publication Date
WO2009019673A2 WO2009019673A2 (fr) 2009-02-12
WO2009019673A3 true WO2009019673A3 (fr) 2016-06-09

Family

ID=40341845

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2007/000987 WO2009019673A2 (fr) 2007-08-07 2007-08-07 Ampoule de mélange multichambre

Country Status (1)

Country Link
WO (1) WO2009019673A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010104858A2 (fr) * 2009-03-09 2010-09-16 Purdue Research Foundation Dispositif compact pour mélanger et distribuer rapidement des substances à un patient
FR3038518A1 (fr) 2015-07-08 2017-01-13 Guerbet Sa Seringue et son procede d'assemblage

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5785683A (en) * 1995-07-17 1998-07-28 Szapiro; Jaime Luis Disposable syringe with two variable volume chambers
US6419656B1 (en) * 1999-03-19 2002-07-16 Arzneimittel Gmbh Apotheker Vetter & Ravensburg Medical syringe with braked step-advance plunger

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5785683A (en) * 1995-07-17 1998-07-28 Szapiro; Jaime Luis Disposable syringe with two variable volume chambers
US6419656B1 (en) * 1999-03-19 2002-07-16 Arzneimittel Gmbh Apotheker Vetter & Ravensburg Medical syringe with braked step-advance plunger

Also Published As

Publication number Publication date
WO2009019673A2 (fr) 2009-02-12

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