WO2009018643A3 - Use of pharmaceutical compound containing crotoxin for the treatment of muscle dystonias - Google Patents

Use of pharmaceutical compound containing crotoxin for the treatment of muscle dystonias Download PDF

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Publication number
WO2009018643A3
WO2009018643A3 PCT/BR2008/000307 BR2008000307W WO2009018643A3 WO 2009018643 A3 WO2009018643 A3 WO 2009018643A3 BR 2008000307 W BR2008000307 W BR 2008000307W WO 2009018643 A3 WO2009018643 A3 WO 2009018643A3
Authority
WO
WIPO (PCT)
Prior art keywords
crotoxin
compound containing
pharmaceutical compound
treatment
muscular
Prior art date
Application number
PCT/BR2008/000307
Other languages
French (fr)
Other versions
WO2009018643A2 (en
Inventor
Geraldo De Barros Ribeiro
Almeida Henderson Celestino De
David Toledo Velarde
Original Assignee
Univ Minas Gerais
Geraldo De Barros Ribeiro
Almeida Henderson Celestino De
David Toledo Velarde
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minas Gerais, Geraldo De Barros Ribeiro, Almeida Henderson Celestino De, David Toledo Velarde filed Critical Univ Minas Gerais
Publication of WO2009018643A2 publication Critical patent/WO2009018643A2/en
Publication of WO2009018643A3 publication Critical patent/WO2009018643A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Abstract

The present invention is related to the use of a pharmaceutical compound containing a toxin extracted from the rattlesnake (Crotalus durissus terrificus) venom, known as crotoxin, which can act as an agent provoking muscular paralysis. Medical uses of this invention formulation are described, which was developed for muscular pathological conditions whose muscular paralysis is desired, such as strabismus, blepharospams, and nystagmus, among others.
PCT/BR2008/000307 2007-08-07 2008-08-06 Use of pharmaceutical compound containing crotoxin for the treatment of muscle dystonias WO2009018643A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0705590-0 2007-08-07
BRPI0705590-0A BRPI0705590B1 (en) 2007-08-07 2007-08-07 USE OF PHARMACEUTICAL COMPOSITION CONTAINING CROTOXIN FOR THE TREATMENT OF MUSCLE DYSTONIA

Publications (2)

Publication Number Publication Date
WO2009018643A2 WO2009018643A2 (en) 2009-02-12
WO2009018643A3 true WO2009018643A3 (en) 2009-03-26

Family

ID=40341798

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2008/000307 WO2009018643A2 (en) 2007-08-07 2008-08-06 Use of pharmaceutical compound containing crotoxin for the treatment of muscle dystonias

Country Status (2)

Country Link
BR (1) BRPI0705590B1 (en)
WO (1) WO2009018643A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2762951T3 (en) * 2015-04-24 2020-05-26 Consiglio Nazionale Ricerche New therapeutic use of serotype A botulinum neurotoxin
RU2761267C1 (en) * 2021-06-18 2021-12-06 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ГБ имени Гельмгольца" Минздрава России) Method for the complex treatment of nystagmus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1391207A1 (en) * 2001-04-24 2004-02-25 Luis Alberto Costa Use of a phospholipase a2 for the preparation of pharmaceutical and/or cosmetic compositions for the local and/or systematic treatment and/or prevention of diseases and/or processes caused by intra- and extracellular pathogens expressing membrane phospholipids
US20060034823A1 (en) * 2004-08-13 2006-02-16 Paul Reid Method of production and use of crotoxin as an analgesic

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1391207A1 (en) * 2001-04-24 2004-02-25 Luis Alberto Costa Use of a phospholipase a2 for the preparation of pharmaceutical and/or cosmetic compositions for the local and/or systematic treatment and/or prevention of diseases and/or processes caused by intra- and extracellular pathogens expressing membrane phospholipids
US20060034823A1 (en) * 2004-08-13 2006-02-16 Paul Reid Method of production and use of crotoxin as an analgesic

Also Published As

Publication number Publication date
BRPI0705590B1 (en) 2021-06-29
WO2009018643A2 (en) 2009-02-12
BRPI0705590A2 (en) 2009-03-24

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