WO2009016519A3 - Bioresorbable implant - Google Patents

Bioresorbable implant Download PDF

Info

Publication number
WO2009016519A3
WO2009016519A3 PCT/IB2008/002989 IB2008002989W WO2009016519A3 WO 2009016519 A3 WO2009016519 A3 WO 2009016519A3 IB 2008002989 W IB2008002989 W IB 2008002989W WO 2009016519 A3 WO2009016519 A3 WO 2009016519A3
Authority
WO
WIPO (PCT)
Prior art keywords
pores
bioresorbable
defines
implant
knit
Prior art date
Application number
PCT/IB2008/002989
Other languages
French (fr)
Other versions
WO2009016519A2 (en
Inventor
Yves Bayon
Philippe Gravagna
Alfredo Meneghin
Michel Therin
Olivier Lefranc
Original Assignee
Sofradim Production
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sofradim Production filed Critical Sofradim Production
Priority to AT08826808T priority Critical patent/ATE549045T1/en
Priority to AU2008281442A priority patent/AU2008281442B2/en
Priority to JP2010518778A priority patent/JP5356384B2/en
Priority to EP08826808A priority patent/EP2183000B1/en
Priority to CA2693977A priority patent/CA2693977C/en
Publication of WO2009016519A2 publication Critical patent/WO2009016519A2/en
Publication of WO2009016519A3 publication Critical patent/WO2009016519A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005Ingredients of undetermined constitution or reaction products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L31/129Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • DTEXTILES; PAPER
    • D04BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04BKNITTING
    • D04B21/00Warp knitting processes for the production of fabrics or articles not dependent on the use of particular machines; Fabrics or articles defined by such processes
    • D04B21/10Open-work fabrics
    • D04B21/12Open-work fabrics characterised by thread material
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2403/00Details of fabric structure established in the fabric forming process
    • D10B2403/01Surface features
    • D10B2403/011Dissimilar front and back faces
    • D10B2403/0112One smooth surface, e.g. laminated or coated
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2403/00Details of fabric structure established in the fabric forming process
    • D10B2403/02Cross-sectional features
    • D10B2403/021Lofty fabric with equidistantly spaced front and back plies, e.g. spacer fabrics
    • D10B2403/0213Lofty fabric with equidistantly spaced front and back plies, e.g. spacer fabrics with apertures, e.g. with one or more mesh fabric plies
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2509/00Medical; Hygiene
    • D10B2509/08Hernia repair mesh

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Composite Materials (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Textile Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)

Abstract

Bioresorbable wall reinforcement implants include a bioresorbable porous matrix based on a collagen sponge which defines first pores, a bioresorbable porous three-dimensional knit which defines second pores, with the matrix filling the knit and all the first and second pores being at least partially interconnected with one another. Tissue engineering supports including such an implant and uses thereof are also described.
PCT/IB2008/002989 2007-07-30 2008-07-30 Bioresorbable implant WO2009016519A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AT08826808T ATE549045T1 (en) 2007-07-30 2008-07-30 BIORESORBOR BRES IMPLANT
AU2008281442A AU2008281442B2 (en) 2007-07-30 2008-07-30 Bioresorbable implant
JP2010518778A JP5356384B2 (en) 2007-07-30 2008-07-30 Bioabsorbable implant
EP08826808A EP2183000B1 (en) 2007-07-30 2008-07-30 Bioresorbable implant
CA2693977A CA2693977C (en) 2007-07-30 2008-07-30 Bioresorbable implant

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/881,838 US8834578B2 (en) 2007-07-30 2007-07-30 Bioresorbable implant
US11/881,838 2007-07-30

Publications (2)

Publication Number Publication Date
WO2009016519A2 WO2009016519A2 (en) 2009-02-05
WO2009016519A3 true WO2009016519A3 (en) 2010-01-07

Family

ID=40304988

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/002989 WO2009016519A2 (en) 2007-07-30 2008-07-30 Bioresorbable implant

Country Status (7)

Country Link
US (1) US8834578B2 (en)
EP (1) EP2183000B1 (en)
JP (1) JP5356384B2 (en)
AT (1) ATE549045T1 (en)
AU (1) AU2008281442B2 (en)
CA (1) CA2693977C (en)
WO (1) WO2009016519A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090036907A1 (en) * 2007-07-30 2009-02-05 Yves Bayon Bioresorbable knit
US8685099B2 (en) * 2007-08-14 2014-04-01 Warsaw Orthopedic, Inc. Multiple component osteoimplant
DE102008044005A1 (en) * 2008-11-24 2010-05-27 Leibniz-Institut Für Polymerforschung Dresden E.V. Planar implant for in abdominal wall region of patient during hernia surgery, has threads with cellular arrangement made in connecting area, where thread aligned parallel to cutting direction, is not present in wound area
FR2949688B1 (en) 2009-09-04 2012-08-24 Sofradim Production FABRIC WITH PICOTS COATED WITH A BIORESORBABLE MICROPOROUS LAYER
AU2011232414A1 (en) 2010-03-24 2012-11-15 Covidien Lp Combination three-dimensional surgical implant
FR2985271B1 (en) 2011-12-29 2014-01-24 Sofradim Production KNITTED PICOTS
FR2985169B1 (en) 2011-12-29 2014-12-05 Sofradim Production KNIT WITH ZONES WITHOUT PICOTS
FR2985170B1 (en) * 2011-12-29 2014-01-24 Sofradim Production PROSTHESIS FOR INGUINAL HERNIA
US11883275B2 (en) 2014-06-11 2024-01-30 Bard Shannon Limited In vivo tissue engineering devices, methods and regenerative and cellular medicine employing scaffolds made of absorbable material
US11638640B2 (en) 2014-06-11 2023-05-02 Bard Shannon Limited In vivo tissue engineering devices, methods and regenerative and cellular medicine employing scaffolds made of absorbable material
US11648135B2 (en) 2017-09-13 2023-05-16 Boston Scientific Scimed, Inc. Coated stent
US11883276B2 (en) 2018-03-12 2024-01-30 Bard Shannon Limited In vivo tissue engineering devices, methods and regenerative and cellular medicine employing scaffolds made of absorbable material
EP3653171B1 (en) 2018-11-16 2024-08-21 Sofradim Production Implants suitable for soft tissue repair
US11065102B2 (en) 2019-02-07 2021-07-20 Biorez, Inc. Composite scaffold for the repair, reconstruction, and regeneration of soft tissues
WO2020255113A1 (en) * 2019-06-20 2020-12-24 Datum Biotech Ltd. An implantable structure having a collagen membrane
WO2021194555A1 (en) 2020-03-23 2021-09-30 Bard Shannon Limited In vivo tissue engineering devices, methods and regenerative and cellular medicine employing scaffolds made of absorbable material
US12064330B2 (en) 2020-04-28 2024-08-20 Covidien Lp Implantable prothesis for minimally invasive hernia repair

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11319068A (en) * 1998-05-12 1999-11-24 Menicon Co Ltd Base material for artificial skin and production thereof
EP0999805A1 (en) * 1997-08-01 2000-05-17 Sofradim Production Three-dimensional open-worked prosthetic fabric
US6391939B2 (en) * 1997-02-06 2002-05-21 Imedex Biomateriaux Collagenic material useful in particular for preventing post-operative adhesions
US6451032B1 (en) * 1997-08-01 2002-09-17 Sofradim Production Composite prosthesis for preventing post-surgical adhesions and method for obtaining same
EP1273312A2 (en) * 2001-07-04 2003-01-08 National Institute of Advanced Industrial Science and Technology Implant for cartilage tissue regeneration
US20040132365A1 (en) * 2002-11-04 2004-07-08 Sofradim Production Intermediate composite part for forming reinforcement prosthesis
EP1535631A2 (en) * 2003-11-25 2005-06-01 Ethicon, Inc. Hemostatic wound dessings containing proteinaceous polymers
WO2006138098A1 (en) * 2005-06-17 2006-12-28 Ethicon, Inc. Reinforced collagen scaffold
US20070032805A1 (en) * 2005-08-03 2007-02-08 Sofradim Production Oxydized cellulose prosthesis

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX163953B (en) * 1984-03-27 1992-07-03 Univ New Jersey Med PROCEDURE FOR PREPARING A BIODEGRADABLE COLLAGEN MATRIX
FR2628634B1 (en) * 1988-03-15 1990-07-13 Imedex VISCERAL SURGERY PATCH
IL110367A (en) * 1994-07-19 2007-05-15 Colbar Lifescience Ltd Collagen-based matrix
FR2724563A1 (en) 1994-09-15 1996-03-22 Coletica USE OF COLLAGENIC MEMBRANES AS PERITONEAL REGENERATION PROSTHESES
US5891558A (en) 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
AUPN174495A0 (en) 1995-03-15 1995-04-06 Ketharanathan, Vettivetpillai Surgical prostheses
US6833408B2 (en) * 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
FR2766716B1 (en) 1997-08-01 2000-02-18 Cogent Sarl COMPOSITE PROSTHESIS FOR PREVENTION OF POST-SURGICAL ADHESIONS AND PROCESS FOR OBTAINING SAME
JP4070954B2 (en) * 1997-10-01 2008-04-02 ボストン サイエンティフィック リミテッド Pelvic floor remodeling
CA2307567C (en) 1997-10-31 2009-01-20 Children's Medical Center Corporation Polymer matrix/cell construct for bladder reconstruction
FR2783429B1 (en) 1998-09-18 2002-04-12 Imedex Biomateriaux BICOMPOSITE COLLAGENIC MATERIAL, ITS OBTAINING PROCESS AND ITS THERAPEUTIC APPLICATIONS
US20030225355A1 (en) 1998-10-01 2003-12-04 Butler Charles E. Composite material for wound repair
US7048753B2 (en) * 1999-03-17 2006-05-23 Poly-Med, Inc. Coated, slow-absorbing textile constructs for sutures and tissue engineering
FR2807937B1 (en) * 2000-04-20 2002-08-02 Sofradim Production GRIPPED PROSTHETIC KNIT, MANUFACTURING METHOD THEREOF AND REINFORCEMENT IMPLANT FOR THE TREATMENT OF WALL DEFICITS
US6790454B1 (en) 2000-05-26 2004-09-14 Coletica Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained
US6974679B2 (en) 2000-05-26 2005-12-13 Coletica Support with collagen base for tissue engineering and manufacture of biomaterials
CA2365376C (en) 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US6599323B2 (en) * 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391939B2 (en) * 1997-02-06 2002-05-21 Imedex Biomateriaux Collagenic material useful in particular for preventing post-operative adhesions
EP0999805A1 (en) * 1997-08-01 2000-05-17 Sofradim Production Three-dimensional open-worked prosthetic fabric
US6443964B1 (en) * 1997-08-01 2002-09-03 Sofradim Production Three-dimensional open-worked prosthetic fabric
US6451032B1 (en) * 1997-08-01 2002-09-17 Sofradim Production Composite prosthesis for preventing post-surgical adhesions and method for obtaining same
JPH11319068A (en) * 1998-05-12 1999-11-24 Menicon Co Ltd Base material for artificial skin and production thereof
EP1273312A2 (en) * 2001-07-04 2003-01-08 National Institute of Advanced Industrial Science and Technology Implant for cartilage tissue regeneration
US20040132365A1 (en) * 2002-11-04 2004-07-08 Sofradim Production Intermediate composite part for forming reinforcement prosthesis
EP1535631A2 (en) * 2003-11-25 2005-06-01 Ethicon, Inc. Hemostatic wound dessings containing proteinaceous polymers
WO2006138098A1 (en) * 2005-06-17 2006-12-28 Ethicon, Inc. Reinforced collagen scaffold
US20070032805A1 (en) * 2005-08-03 2007-02-08 Sofradim Production Oxydized cellulose prosthesis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE EPODOC EUROPEAN PATENT OFFICE, THE HAGUE, NL; XP002554917 *

Also Published As

Publication number Publication date
AU2008281442B2 (en) 2014-05-01
CA2693977A1 (en) 2009-02-05
WO2009016519A2 (en) 2009-02-05
EP2183000A2 (en) 2010-05-12
US8834578B2 (en) 2014-09-16
EP2183000B1 (en) 2012-03-14
AU2008281442A1 (en) 2009-02-05
JP2010535052A (en) 2010-11-18
CA2693977C (en) 2017-07-11
ATE549045T1 (en) 2012-03-15
US20090036997A1 (en) 2009-02-05
JP5356384B2 (en) 2013-12-04

Similar Documents

Publication Publication Date Title
WO2009016519A3 (en) Bioresorbable implant
WO2009016518A3 (en) Biological mesh tissue engineering support
WO2008109807A3 (en) Bone void filler
WO2009099559A3 (en) Porous biocompatible polymer material and methods
WO2006084040A3 (en) Engineering vascularized muscle tissue
WO2009022231A3 (en) Reinforced composite implant
WO2007055761A3 (en) Hydrophillic polymer dental sponge
WO2008034007A3 (en) Medical devices
WO2007041617A3 (en) Bioactive composite spinal implants
WO2008021127A3 (en) Expandable cartilage implant
WO2005086939A3 (en) Systems for bone replacement
WO2011011785A3 (en) Porous composite implant based on ceramic and polymeric filler material
PL1787626T3 (en) Injectable, self-setting calcium phosphate foam
WO2009156866A3 (en) Biosynthetic implant for soft tissue repair
WO2007012070A3 (en) Improvements in and relating to implants
EP1887948A4 (en) Bone implants with integrated line locks
ATE539710T1 (en) ANTERIOR HYBRID IMPLANT
WO2009120966A3 (en) Reinforced tissue graft
WO2010078037A3 (en) Full-metal dampening intervertebral implant
FI20045223A0 (en) A multifunctional biodegradable composite and a surgical implant comprising said composite
WO2008091835A3 (en) Implantable medical endoprostheses
WO2009105246A3 (en) Biostaples suitable for wrist, hand and other ligament replacements or repairs
WO2008096363A3 (en) Bone implant
WO2008106625A3 (en) Porous composite biomaterials and related methods
WO2009125402A3 (en) Bone-like prosthetic implants

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 2693977

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2008281442

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2010518778

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2008281442

Country of ref document: AU

Date of ref document: 20080730

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2008826808

Country of ref document: EP

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08826808

Country of ref document: EP

Kind code of ref document: A2