WO2009008236A1 - マイクロ検査チップの液体混合方法および検査装置 - Google Patents
マイクロ検査チップの液体混合方法および検査装置 Download PDFInfo
- Publication number
- WO2009008236A1 WO2009008236A1 PCT/JP2008/060444 JP2008060444W WO2009008236A1 WO 2009008236 A1 WO2009008236 A1 WO 2009008236A1 JP 2008060444 W JP2008060444 W JP 2008060444W WO 2009008236 A1 WO2009008236 A1 WO 2009008236A1
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- liquids
- mixing liquids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
- B01F25/451—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
- B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
- B01F25/4521—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through orifices in elements, e.g. flat plates or cylinders, which obstruct the whole diameter of the tube
- B01F25/45211—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through orifices in elements, e.g. flat plates or cylinders, which obstruct the whole diameter of the tube the elements being cylinders or cones which obstruct the whole diameter of the tube, the flow changing from axial in radial and again in axial
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/712—Feed mechanisms for feeding fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/71745—Feed mechanisms characterised by the means for feeding the components to the mixer using pneumatic pressure, overpressure, gas or air pressure in a closed receptacle or circuit system
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00889—Mixing
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Micromachines (AREA)
Abstract
異なる液体を直列に接触させ、その前後を空気で挟んで混合流路内を一方向に送液することで、混合流路の壁面のせん断力と液体と空気との界面の表面張力とによる動きを利用して液体を混合することができるので、異なる液体を効率よく混合することのできるマイクロ検査チップの液体混合方法および検査装置を提供することができる。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009522560A JPWO2009008236A1 (ja) | 2007-07-10 | 2008-06-06 | マイクロ検査チップの液体混合方法および検査装置 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-180742 | 2007-07-10 | ||
JP2007180742 | 2007-07-10 |
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WO2009008236A1 true WO2009008236A1 (ja) | 2009-01-15 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/JP2008/060444 WO2009008236A1 (ja) | 2007-07-10 | 2008-06-06 | マイクロ検査チップの液体混合方法および検査装置 |
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WO (1) | WO2009008236A1 (ja) |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8388908B2 (en) | 2009-06-02 | 2013-03-05 | Integenx Inc. | Fluidic devices with diaphragm valves |
US8394642B2 (en) | 2009-06-05 | 2013-03-12 | Integenx Inc. | Universal sample preparation system and use in an integrated analysis system |
US8431340B2 (en) | 2004-09-15 | 2013-04-30 | Integenx Inc. | Methods for processing and analyzing nucleic acid samples |
US8476063B2 (en) | 2004-09-15 | 2013-07-02 | Integenx Inc. | Microfluidic devices |
US8512538B2 (en) | 2010-05-28 | 2013-08-20 | Integenx Inc. | Capillary electrophoresis device |
US8557518B2 (en) | 2007-02-05 | 2013-10-15 | Integenx Inc. | Microfluidic and nanofluidic devices, systems, and applications |
US8584703B2 (en) | 2009-12-01 | 2013-11-19 | Integenx Inc. | Device with diaphragm valve |
US8672532B2 (en) | 2008-12-31 | 2014-03-18 | Integenx Inc. | Microfluidic methods |
US8748165B2 (en) | 2008-01-22 | 2014-06-10 | Integenx Inc. | Methods for generating short tandem repeat (STR) profiles |
US8763642B2 (en) | 2010-08-20 | 2014-07-01 | Integenx Inc. | Microfluidic devices with mechanically-sealed diaphragm valves |
US9121058B2 (en) | 2010-08-20 | 2015-09-01 | Integenx Inc. | Linear valve arrays |
US10191071B2 (en) | 2013-11-18 | 2019-01-29 | IntegenX, Inc. | Cartridges and instruments for sample analysis |
US10208332B2 (en) | 2014-05-21 | 2019-02-19 | Integenx Inc. | Fluidic cartridge with valve mechanism |
US10525467B2 (en) | 2011-10-21 | 2020-01-07 | Integenx Inc. | Sample preparation, processing and analysis systems |
JP2020034333A (ja) * | 2018-08-28 | 2020-03-05 | 京セラ株式会社 | 液体供給デバイス |
US10690627B2 (en) | 2014-10-22 | 2020-06-23 | IntegenX, Inc. | Systems and methods for sample preparation, processing and analysis |
JP2020190575A (ja) * | 2020-08-25 | 2020-11-26 | ソニー株式会社 | 粒子分取装置及び粒子分取方法 |
US10865440B2 (en) | 2011-10-21 | 2020-12-15 | IntegenX, Inc. | Sample preparation, processing and analysis systems |
JP2021510627A (ja) * | 2018-01-15 | 2021-04-30 | ローベルト ボツシユ ゲゼルシヤフト ミツト ベシユレンクテル ハフツングRobert Bosch Gmbh | マイクロ流体デバイスおよび該マイクロ流体デバイスを運転する方法 |
US11305318B2 (en) | 2013-04-04 | 2022-04-19 | Sony Corporation | Particle sorting apparatus and particle sorting method |
Citations (5)
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JP2005199238A (ja) * | 2004-01-19 | 2005-07-28 | Kri Inc | 微粒子製造装置 |
JP2006504512A (ja) * | 2002-05-09 | 2006-02-09 | ザ ユニバーシティー オブ シカゴ | 圧力駆動プラグによる輸送と反応のための装置および方法 |
JP2006053091A (ja) * | 2004-08-13 | 2006-02-23 | Alps Electric Co Ltd | プレート |
JP2006247533A (ja) * | 2005-03-10 | 2006-09-21 | Bussan Nanotech Research Institute Inc | マイクロチャネルチップ |
JP2007155491A (ja) * | 2005-12-05 | 2007-06-21 | Seiko Instruments Inc | マイクロリアクターシステム及び送液方法 |
-
2008
- 2008-06-06 WO PCT/JP2008/060444 patent/WO2009008236A1/ja active Application Filing
- 2008-06-06 JP JP2009522560A patent/JPWO2009008236A1/ja active Pending
Patent Citations (5)
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JP2006504512A (ja) * | 2002-05-09 | 2006-02-09 | ザ ユニバーシティー オブ シカゴ | 圧力駆動プラグによる輸送と反応のための装置および方法 |
JP2005199238A (ja) * | 2004-01-19 | 2005-07-28 | Kri Inc | 微粒子製造装置 |
JP2006053091A (ja) * | 2004-08-13 | 2006-02-23 | Alps Electric Co Ltd | プレート |
JP2006247533A (ja) * | 2005-03-10 | 2006-09-21 | Bussan Nanotech Research Institute Inc | マイクロチャネルチップ |
JP2007155491A (ja) * | 2005-12-05 | 2007-06-21 | Seiko Instruments Inc | マイクロリアクターシステム及び送液方法 |
Cited By (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8551714B2 (en) | 2004-09-15 | 2013-10-08 | Integenx Inc. | Microfluidic devices |
US8431340B2 (en) | 2004-09-15 | 2013-04-30 | Integenx Inc. | Methods for processing and analyzing nucleic acid samples |
US8431390B2 (en) | 2004-09-15 | 2013-04-30 | Integenx Inc. | Systems of sample processing having a macro-micro interface |
US8476063B2 (en) | 2004-09-15 | 2013-07-02 | Integenx Inc. | Microfluidic devices |
US9752185B2 (en) | 2004-09-15 | 2017-09-05 | Integenx Inc. | Microfluidic devices |
US8557518B2 (en) | 2007-02-05 | 2013-10-15 | Integenx Inc. | Microfluidic and nanofluidic devices, systems, and applications |
US8748165B2 (en) | 2008-01-22 | 2014-06-10 | Integenx Inc. | Methods for generating short tandem repeat (STR) profiles |
US8672532B2 (en) | 2008-12-31 | 2014-03-18 | Integenx Inc. | Microfluidic methods |
US8388908B2 (en) | 2009-06-02 | 2013-03-05 | Integenx Inc. | Fluidic devices with diaphragm valves |
US8562918B2 (en) | 2009-06-05 | 2013-10-22 | Integenx Inc. | Universal sample preparation system and use in an integrated analysis system |
US8394642B2 (en) | 2009-06-05 | 2013-03-12 | Integenx Inc. | Universal sample preparation system and use in an integrated analysis system |
US9012236B2 (en) | 2009-06-05 | 2015-04-21 | Integenx Inc. | Universal sample preparation system and use in an integrated analysis system |
US8584703B2 (en) | 2009-12-01 | 2013-11-19 | Integenx Inc. | Device with diaphragm valve |
US8512538B2 (en) | 2010-05-28 | 2013-08-20 | Integenx Inc. | Capillary electrophoresis device |
US9121058B2 (en) | 2010-08-20 | 2015-09-01 | Integenx Inc. | Linear valve arrays |
US9731266B2 (en) | 2010-08-20 | 2017-08-15 | Integenx Inc. | Linear valve arrays |
US8763642B2 (en) | 2010-08-20 | 2014-07-01 | Integenx Inc. | Microfluidic devices with mechanically-sealed diaphragm valves |
US10865440B2 (en) | 2011-10-21 | 2020-12-15 | IntegenX, Inc. | Sample preparation, processing and analysis systems |
US10525467B2 (en) | 2011-10-21 | 2020-01-07 | Integenx Inc. | Sample preparation, processing and analysis systems |
US11684918B2 (en) | 2011-10-21 | 2023-06-27 | IntegenX, Inc. | Sample preparation, processing and analysis systems |
US11305318B2 (en) | 2013-04-04 | 2022-04-19 | Sony Corporation | Particle sorting apparatus and particle sorting method |
US10191071B2 (en) | 2013-11-18 | 2019-01-29 | IntegenX, Inc. | Cartridges and instruments for sample analysis |
US10989723B2 (en) | 2013-11-18 | 2021-04-27 | IntegenX, Inc. | Cartridges and instruments for sample analysis |
US10961561B2 (en) | 2014-05-21 | 2021-03-30 | IntegenX, Inc. | Fluidic cartridge with valve mechanism |
US10208332B2 (en) | 2014-05-21 | 2019-02-19 | Integenx Inc. | Fluidic cartridge with valve mechanism |
US11891650B2 (en) | 2014-05-21 | 2024-02-06 | IntegenX, Inc. | Fluid cartridge with valve mechanism |
US10690627B2 (en) | 2014-10-22 | 2020-06-23 | IntegenX, Inc. | Systems and methods for sample preparation, processing and analysis |
JP2021510627A (ja) * | 2018-01-15 | 2021-04-30 | ローベルト ボツシユ ゲゼルシヤフト ミツト ベシユレンクテル ハフツングRobert Bosch Gmbh | マイクロ流体デバイスおよび該マイクロ流体デバイスを運転する方法 |
JP7171739B2 (ja) | 2018-01-15 | 2022-11-15 | ローベルト ボツシユ ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | マイクロ流体デバイスおよび該マイクロ流体デバイスを運転する方法 |
JP2020034333A (ja) * | 2018-08-28 | 2020-03-05 | 京セラ株式会社 | 液体供給デバイス |
JP2020190575A (ja) * | 2020-08-25 | 2020-11-26 | ソニー株式会社 | 粒子分取装置及び粒子分取方法 |
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JPWO2009008236A1 (ja) | 2010-09-02 |
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