WO2008157203A3 - Methods of protecting animals from avian influenza infection - Google Patents

Methods of protecting animals from avian influenza infection Download PDF

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Publication number
WO2008157203A3
WO2008157203A3 PCT/US2008/066645 US2008066645W WO2008157203A3 WO 2008157203 A3 WO2008157203 A3 WO 2008157203A3 US 2008066645 W US2008066645 W US 2008066645W WO 2008157203 A3 WO2008157203 A3 WO 2008157203A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
avian
vaccine composition
avian influenza
influenza infection
Prior art date
Application number
PCT/US2008/066645
Other languages
French (fr)
Other versions
WO2008157203A2 (en
Inventor
Javaraiah Srinivas
Chengjin Huang
Michael A Gill
Hsien-Jue Chu
Original Assignee
Wyeth Corp
Javaraiah Srinivas
Chengjin Huang
Michael A Gill
Hsien-Jue Chu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp, Javaraiah Srinivas, Chengjin Huang, Michael A Gill, Hsien-Jue Chu filed Critical Wyeth Corp
Publication of WO2008157203A2 publication Critical patent/WO2008157203A2/en
Publication of WO2008157203A3 publication Critical patent/WO2008157203A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention provides methods of vaccinating non-avian, non-human animals against avian influenza. The methods of the invention comprise administering to the animal at least one dose of a vaccine composition comprising an immunologically-effective amount of an inactivated influenza virus. The influenza virus may contain any combination of hemagglutinin and neuraminidase subtypes. An exemplary inactivated influenza virus for use in a vaccine composition of the invention is a reverse genetics H5N3 virus. The animals to which the vaccine composition is administered may be any non-avian, non-human animal such as a dog, a cat or a pig.
PCT/US2008/066645 2007-06-15 2008-06-12 Methods of protecting animals from avian influenza infection WO2008157203A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93464107P 2007-06-15 2007-06-15
US60/934,641 2007-06-15

Publications (2)

Publication Number Publication Date
WO2008157203A2 WO2008157203A2 (en) 2008-12-24
WO2008157203A3 true WO2008157203A3 (en) 2009-05-07

Family

ID=39798223

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/066645 WO2008157203A2 (en) 2007-06-15 2008-06-12 Methods of protecting animals from avian influenza infection

Country Status (1)

Country Link
WO (1) WO2008157203A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9956281B2 (en) * 2011-05-04 2018-05-01 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
WO2023196741A1 (en) * 2022-04-08 2023-10-12 The United States Of America, As Represented By The Secretary Of Agriculture Avian influenza vaccines and methods of making same

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"Frequently asked questions with regard to the Avian flu, answered by Intervet International", 1 March 2006, INTERVET, XP002499624 *
HORIMOTO ET AL: "The development and characterization of H5 influenza virus vaccines derived from a 2003 human isolate", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 24, no. 17, 24 April 2006 (2006-04-24), pages 3669 - 3676, XP005353720, ISSN: 0264-410X *
KARACA KEMAL ET AL: "Immunogenicity of fowlpox virus expressing the avian influenza virus H5 gene (TROVAC AIV-H5) in cats", CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 12, no. 11, 1 November 2005 (2005-11-01), pages 1340 - 1342, XP002434626, ISSN: 1071-412X *
LU XIUHUA ET AL: "Cross-protective immunity in mice induced by live-attenuated or inactivated vaccines against highly pathogenic influenza A (H5N1) viruses", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 24, no. 44-46, 5 June 2006 (2006-06-05), pages 6588 - 6593, XP002420313, ISSN: 0264-410X *

Also Published As

Publication number Publication date
WO2008157203A2 (en) 2008-12-24

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