WO2008155998A1 - Antianxiety/antidepressant agent - Google Patents

Antianxiety/antidepressant agent Download PDF

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Publication number
WO2008155998A1
WO2008155998A1 PCT/JP2008/060477 JP2008060477W WO2008155998A1 WO 2008155998 A1 WO2008155998 A1 WO 2008155998A1 JP 2008060477 W JP2008060477 W JP 2008060477W WO 2008155998 A1 WO2008155998 A1 WO 2008155998A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
antianxiety
antidepressant
antidepressant agent
activity
agent
Prior art date
Application number
PCT/JP2008/060477
Other languages
French (fr)
Japanese (ja)
Inventor
Eiji Takeda
Junji Terao
Hiroyoshi Sei
Hiroyuki Sakakibara
Kazuyoshi Kitaoka
Toshitsugu Miyazaki
Chieko Kitajima
Original Assignee
Nagase & Co., Ltd.
The University Of Tokushima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Abstract

Disclosed are: an antianxiety/antidepressant agent which has a satisfactory level of an antianxiety activity and/or an antidepressant activity; and a food or beverage comprising the antianxiety/antidepressant agent. Specifically disclosed is an antianxiety/antidepressant agent comprising a fermented ginseng extract and/or a component produced from the fermented ginseng extract as an active ingredient. Also specifically disclosed is a food or beverage bearing a notice as being used for the prevention or treatment of anxiety or depression, which is characterized by comprising the antianxiety/antidepressant agent and having an antianxiety/antidepressant activity.
PCT/JP2008/060477 2007-06-21 2008-06-06 Antianxiety/antidepressant agent WO2008155998A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2007164183 2007-06-21
JP2007164034 2007-06-21
JP2007-164034 2007-06-21
JP2007-164183 2007-06-21

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009520423A JPWO2008155998A1 (en) 2007-06-21 2008-06-06 Anti-anxiety antidepressants

Publications (1)

Publication Number Publication Date
WO2008155998A1 true true WO2008155998A1 (en) 2008-12-24

Family

ID=40156157

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/060477 WO2008155998A1 (en) 2007-06-21 2008-06-06 Antianxiety/antidepressant agent

Country Status (2)

Country Link
JP (1) JPWO2008155998A1 (en)
WO (1) WO2008155998A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011121926A (en) * 2009-12-14 2011-06-23 Lion Corp Composition including at least either one of protopanaxatriol and protopanaxadiol
JP2013529899A (en) * 2010-05-14 2013-07-25 株式会社ジーシーエイチアンドピーGreencross Herb & Pharmaceutical Co.,Ltd. Method for producing a novel processed ginseng or processed ginseng extract increased the ginsenoside components
JP2015168614A (en) * 2014-03-04 2015-09-28 長瀬産業株式会社 Glp-1 secretion enhancer
JP2016508489A (en) * 2013-01-31 2016-03-22 シャンハイ イノベーティブ リサーチ センター オブ トラディショナル チャイニーズ メディスン Protopanaxadiol derivatives, their preparation and their applications
KR101641509B1 (en) * 2015-01-22 2016-07-21 샘표 주식회사 A composition for anti-stress containing aglycone ppd and/or ppt

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1099094A (en) * 1996-09-25 1998-04-21 Happy World:Kk Production of ginseng saponin metabolites
JP2004049154A (en) * 2002-07-23 2004-02-19 Hideo Hasegawa Fermented carrot containing decomposed product of saponin and method for producing the same
JP2005160373A (en) * 2003-12-02 2005-06-23 Hideo Hasegawa Glycoside-degradative probiotics
JP2006508660A (en) * 2002-12-05 2006-03-16 ホングリム トレーディング カンパニー リミテッドHongrim Trading Co.,Ltd. Ginseng lactobacillus fermentation product, a strain of ginseng yogurt and lactic acid bacteria is utilized to it containing the same
JP2008000102A (en) * 2006-06-26 2008-01-10 Bio Ken:Kk Spawn for producing yoghurt

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006115307A1 (en) * 2005-04-26 2006-11-02 Ko, Boong-Kyung Method of extracting ginsengnoside rg2m, pharmaceutical composition including ginsengnoside rg2, and uses thereof
CN100438876C (en) * 2006-06-09 2008-12-03 上海中药创新研究中心 Use of 20(S)-protopanoxadiol in preparation of antidepressant medicine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1099094A (en) * 1996-09-25 1998-04-21 Happy World:Kk Production of ginseng saponin metabolites
JP2004049154A (en) * 2002-07-23 2004-02-19 Hideo Hasegawa Fermented carrot containing decomposed product of saponin and method for producing the same
JP2006508660A (en) * 2002-12-05 2006-03-16 ホングリム トレーディング カンパニー リミテッドHongrim Trading Co.,Ltd. Ginseng lactobacillus fermentation product, a strain of ginseng yogurt and lactic acid bacteria is utilized to it containing the same
JP2005160373A (en) * 2003-12-02 2005-06-23 Hideo Hasegawa Glycoside-degradative probiotics
JP2008000102A (en) * 2006-06-26 2008-01-10 Bio Ken:Kk Spawn for producing yoghurt

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HASEGAWA H.: "Kanpo to Probiotic", IGAKU NO AYUMI, vol. 207, no. 10, 2003, pages 857 - 861 *
PARK J.-H. ET AL.: "Anxiolytic-like effects of ginseng in the elevated plus-maze model: Comparison of red dinseng and sun ginseng", PROGRESS IN NEURO-PSYCHOPHARMACOLOGY AND BIOLOGICAL PSYCHIATRY, vol. 29, no. 6, July 2005 (2005-07-01), pages 895 - 900 *
TACHIKAWA E. ET AL.: "In vitro inhibition of adrenal catecholamine secretion by steroidal metabolites of ginseng saponins", BIOCHEMICAL PHARMACOLOGY, vol. 66, no. 11, 2003, pages 2213 - 2221 *
WEI X.-Y. ET AL.: "Anxiolytic effect of saponins from Panax quinquefolium in mice", J. ETHNOPHARMACOL., vol. 111, no. 3, 22 May 2007 (2007-05-22), pages 613 - 618 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011121926A (en) * 2009-12-14 2011-06-23 Lion Corp Composition including at least either one of protopanaxatriol and protopanaxadiol
JP2013529899A (en) * 2010-05-14 2013-07-25 株式会社ジーシーエイチアンドピーGreencross Herb & Pharmaceutical Co.,Ltd. Method for producing a novel processed ginseng or processed ginseng extract increased the ginsenoside components
US9512453B2 (en) 2010-05-14 2016-12-06 Green Cross Wellbeing Corporation Method for preparing novel processed ginseng or an extract thereof, the usually minute ginsenoside content of which is increased
JP2016508489A (en) * 2013-01-31 2016-03-22 シャンハイ イノベーティブ リサーチ センター オブ トラディショナル チャイニーズ メディスン Protopanaxadiol derivatives, their preparation and their applications
JP2015168614A (en) * 2014-03-04 2015-09-28 長瀬産業株式会社 Glp-1 secretion enhancer
KR101641509B1 (en) * 2015-01-22 2016-07-21 샘표 주식회사 A composition for anti-stress containing aglycone ppd and/or ppt

Also Published As

Publication number Publication date Type
JPWO2008155998A1 (en) 2010-08-26 application

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