WO2008155512A3 - Stabilized wound dressing - Google Patents

Stabilized wound dressing Download PDF

Info

Publication number
WO2008155512A3
WO2008155512A3 PCT/GB2008/001611 GB2008001611W WO2008155512A3 WO 2008155512 A3 WO2008155512 A3 WO 2008155512A3 GB 2008001611 W GB2008001611 W GB 2008001611W WO 2008155512 A3 WO2008155512 A3 WO 2008155512A3
Authority
WO
WIPO (PCT)
Prior art keywords
ascorbate
wound dressing
solvent
polyphosphate
stabilized
Prior art date
Application number
PCT/GB2008/001611
Other languages
French (fr)
Other versions
WO2008155512A2 (en
Inventor
Stuart Boothman
Terry Donnelly
Original Assignee
Systagenix Wound Management Ip Co. B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Systagenix Wound Management Ip Co. B.V. filed Critical Systagenix Wound Management Ip Co. B.V.
Publication of WO2008155512A2 publication Critical patent/WO2008155512A2/en
Publication of WO2008155512A3 publication Critical patent/WO2008155512A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A wound dressing material comprising an ascorbate 2-polyphosphate compound. Preferably, the wound dressing material comprises a freeze-dried or solvent-dried polymer sponge having the ascorbate 2-polyphosphate compound dispersed therein. Preferably the ascorbate is L-ascorbate 2-triphosphate. Also provided are methods of making such materials by dispersing one or more polymers and the ascorbate 2- polyphosphate in an aqueous solvent, followed by freeze drying or solvent drying the dispersion.
PCT/GB2008/001611 2007-06-18 2008-02-09 Stabilized wound dressing WO2008155512A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0711802.9 2007-06-18
GB0711802A GB2450477A (en) 2007-06-18 2007-06-18 Stabilized wound dressing

Publications (2)

Publication Number Publication Date
WO2008155512A2 WO2008155512A2 (en) 2008-12-24
WO2008155512A3 true WO2008155512A3 (en) 2009-11-05

Family

ID=38332331

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2008/001611 WO2008155512A2 (en) 2007-06-18 2008-02-09 Stabilized wound dressing

Country Status (2)

Country Link
GB (1) GB2450477A (en)
WO (1) WO2008155512A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009104005A1 (en) * 2008-02-22 2009-08-27 Technostics Limited Chronic wound treatment
US8034363B2 (en) 2008-12-11 2011-10-11 Advanced Technologies And Regenerative Medicine, Llc. Sustained release systems of ascorbic acid phosphate
GB2470040A (en) * 2009-05-06 2010-11-10 Systagenix Wound Man Ip Co Bv Wound dressing material comprising N-acetyl cysteine
CN102921034A (en) * 2012-12-04 2013-02-13 广州创尔生物技术有限公司 Composite dressing of pig accellular dermal matrix and preparation method of composite dressing
CN109675119A (en) * 2019-01-14 2019-04-26 深圳齐康医疗器械有限公司 A kind of artificial dermis and preparation method thereof for chronic wound treatment

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002001954A1 (en) * 2000-07-05 2002-01-10 The Board Of Trustees Of The University Of Arkansas Use of ascorbic acid and salts of ascorbic acid to promote cell repair and regeneration after injury
US20040001878A1 (en) * 2002-06-26 2004-01-01 Deroyal Industries, Inc. Infused wound care dressings
US20040247633A1 (en) * 2003-06-04 2004-12-09 Ebersytes, Llc Novel dermatological composition
GB2425474A (en) * 2005-04-26 2006-11-01 Ethicon Inc Photostable wound dressing materials and methods of production thereof
DE102007030931A1 (en) * 2007-07-03 2009-01-08 Birgit Riesinger Composition containing at least one nutritive, at least one disinfecting or decontaminating and / or at least one protease inhibiting active substance and / or active substance complex

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04346926A (en) * 1991-05-21 1992-12-02 Sumitomo Pharmaceut Co Ltd Syrup agent
JPH08291075A (en) * 1995-04-20 1996-11-05 Showa Denko Kk Cancer metastasis inhibitor
EP0875246A1 (en) * 1997-04-04 1998-11-04 Showa Denko Kabushiki Kaisha Pharmaceutical preparation of ascorbic acid derivatives for medical treatment of cancer
JP2000212082A (en) * 1999-01-26 2000-08-02 Showa Denko Kk Preparation for external use for skin
JP4349772B2 (en) * 2000-04-12 2009-10-21 ザ プロクター アンド ギャンブル カンパニー Pre-formed sheet applicator suitable for topical application
DE10054479A1 (en) * 2000-11-03 2002-05-08 Henkel Kgaa Cosmetic plasters for skin lightening
KR20040002855A (en) * 2001-01-24 2004-01-07 오라세우티칼, 엘엘씨 Topical oral care compositions
JP2005023040A (en) * 2003-07-04 2005-01-27 Okayama Taiho Pharmaceutical Co Ltd Dermatological plaster

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002001954A1 (en) * 2000-07-05 2002-01-10 The Board Of Trustees Of The University Of Arkansas Use of ascorbic acid and salts of ascorbic acid to promote cell repair and regeneration after injury
US20040001878A1 (en) * 2002-06-26 2004-01-01 Deroyal Industries, Inc. Infused wound care dressings
US20040247633A1 (en) * 2003-06-04 2004-12-09 Ebersytes, Llc Novel dermatological composition
GB2425474A (en) * 2005-04-26 2006-11-01 Ethicon Inc Photostable wound dressing materials and methods of production thereof
DE102007030931A1 (en) * 2007-07-03 2009-01-08 Birgit Riesinger Composition containing at least one nutritive, at least one disinfecting or decontaminating and / or at least one protease inhibiting active substance and / or active substance complex

Also Published As

Publication number Publication date
GB2450477A (en) 2008-12-31
GB0711802D0 (en) 2007-07-25
WO2008155512A2 (en) 2008-12-24

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