WO2008153429A3 - A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use - Google Patents

A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use Download PDF

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Publication number
WO2008153429A3
WO2008153429A3 PCT/PL2008/000042 PL2008000042W WO2008153429A3 WO 2008153429 A3 WO2008153429 A3 WO 2008153429A3 PL 2008000042 W PL2008000042 W PL 2008000042W WO 2008153429 A3 WO2008153429 A3 WO 2008153429A3
Authority
WO
WIPO (PCT)
Prior art keywords
spib
spia
staphylococcus aureus
recognises
protease
Prior art date
Application number
PCT/PL2008/000042
Other languages
French (fr)
Other versions
WO2008153429A2 (en
Inventor
Grzegorz Dubin
Jan Potempa
Original Assignee
Univ Jagiellonski
Biocentrum Sp Z O O
Grzegorz Dubin
Jan Potempa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PL382638A external-priority patent/PL214451B1/en
Priority claimed from PL382770A external-priority patent/PL221052B1/en
Application filed by Univ Jagiellonski, Biocentrum Sp Z O O, Grzegorz Dubin, Jan Potempa filed Critical Univ Jagiellonski
Publication of WO2008153429A2 publication Critical patent/WO2008153429A2/en
Publication of WO2008153429A3 publication Critical patent/WO2008153429A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The invention discloses a method of obtaining proteases from Staphylococcus aureus, particularly the proteases SpIA or SpIB, their use in the specific hydrolysis of a polypeptide chain, amino-acid sequence recognized by them and their use.
PCT/PL2008/000042 2007-06-11 2008-06-11 A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use WO2008153429A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PLPL382638 2007-06-11
PL382638A PL214451B1 (en) 2007-06-11 2007-06-11 Proteinase Sp1B and peptides identified by it and their applications
PL382770A PL221052B1 (en) 2007-06-28 2007-06-28 Proteinase Sp1A and peptides recognized by it and their application
PLPL382770 2007-06-28

Publications (2)

Publication Number Publication Date
WO2008153429A2 WO2008153429A2 (en) 2008-12-18
WO2008153429A3 true WO2008153429A3 (en) 2009-05-07

Family

ID=39928843

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/PL2008/000042 WO2008153429A2 (en) 2007-06-11 2008-06-11 A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use

Country Status (1)

Country Link
WO (1) WO2008153429A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8889633B2 (en) 2013-03-15 2014-11-18 Mead Johnson Nutrition Company Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof
US9289461B2 (en) 2013-03-15 2016-03-22 Mead Johnson Nutrition Company Reducing the risk of autoimmune disease
US9352020B2 (en) 2013-03-15 2016-05-31 Mead Johnson Nutrition Company Reducing proinflammatory response
US9138455B2 (en) 2013-03-15 2015-09-22 Mead Johnson Nutrition Company Activating adiponectin by casein hydrolysate
CN108794570B (en) * 2018-06-15 2021-08-06 华南理工大学 Xanthine oxidase inhibitor containing phenylalanine and application thereof
US20220185852A1 (en) * 2020-12-11 2022-06-16 Bayer Animal Health Gmbh Methods and compositions for improved production of an antigen for use in an s. aureus vaccine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065878A1 (en) * 2005-08-31 2007-03-22 Daugherty Patrick S Cellular libraries of peptide sequences (CLiPS) and methods of using the same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065878A1 (en) * 2005-08-31 2007-03-22 Daugherty Patrick S Cellular libraries of peptide sequences (CLiPS) and methods of using the same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOULWARE K.T. ET AL.: "Protease specificity determination by using cellular libraries of peptide substrates (CLiPS)", P.N.A.S, vol. 103, 16 August 2006 (2006-08-16), pages 7583 - 7588, XP002503593 *
DUBIN G ET AL: "Enzymatic Activity of the Staphylococcus aureus SplB Serine Protease is Induced by Substrates Containing the Sequence Trp-Glu-Leu-Gln", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 379, no. 2, 29 May 2008 (2008-05-29), pages 343 - 356, XP022648469, ISSN: 0022-2836, [retrieved on 20080403] *
POPOWICZ ET AL: "Functional and Structural Characterization of Spl Proteases from Staphylococcus aureus", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 358, no. 1, 21 April 2006 (2006-04-21), pages 270 - 279, XP005345774, ISSN: 0022-2836 *

Also Published As

Publication number Publication date
WO2008153429A2 (en) 2008-12-18

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