WO2008153429A3 - A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use - Google Patents

A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use Download PDF

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Publication number
WO2008153429A3
WO2008153429A3 PCT/PL2008/000042 PL2008000042W WO2008153429A3 WO 2008153429 A3 WO2008153429 A3 WO 2008153429A3 PL 2008000042 W PL2008000042 W PL 2008000042W WO 2008153429 A3 WO2008153429 A3 WO 2008153429A3
Authority
WO
WIPO (PCT)
Prior art keywords
spib
spia
staphylococcus aureus
recognises
protease
Prior art date
Application number
PCT/PL2008/000042
Other languages
French (fr)
Other versions
WO2008153429A2 (en
Inventor
Grzegorz Dubin
Jan Potempa
Original Assignee
Univ Jagiellonski
Biocentrum Sp Z O O
Grzegorz Dubin
Jan Potempa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PL382638A external-priority patent/PL214451B1/en
Priority claimed from PL382770A external-priority patent/PL221052B1/en
Application filed by Univ Jagiellonski, Biocentrum Sp Z O O, Grzegorz Dubin, Jan Potempa filed Critical Univ Jagiellonski
Publication of WO2008153429A2 publication Critical patent/WO2008153429A2/en
Publication of WO2008153429A3 publication Critical patent/WO2008153429A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The invention discloses a method of obtaining proteases from Staphylococcus aureus, particularly the proteases SpIA or SpIB, their use in the specific hydrolysis of a polypeptide chain, amino-acid sequence recognized by them and their use.
PCT/PL2008/000042 2007-06-11 2008-06-11 A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use WO2008153429A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PL382638A PL214451B1 (en) 2007-06-11 2007-06-11 Proteinase Sp1B and peptides identified by it and their applications
PLPL382638 2007-06-11
PLPL382770 2007-06-28
PL382770A PL221052B1 (en) 2007-06-28 2007-06-28 Proteinase Sp1A and peptides recognized by it and their application

Publications (2)

Publication Number Publication Date
WO2008153429A2 WO2008153429A2 (en) 2008-12-18
WO2008153429A3 true WO2008153429A3 (en) 2009-05-07

Family

ID=39928843

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/PL2008/000042 WO2008153429A2 (en) 2007-06-11 2008-06-11 A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use

Country Status (1)

Country Link
WO (1) WO2008153429A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8889633B2 (en) 2013-03-15 2014-11-18 Mead Johnson Nutrition Company Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof
US9138455B2 (en) 2013-03-15 2015-09-22 Mead Johnson Nutrition Company Activating adiponectin by casein hydrolysate
US9352020B2 (en) 2013-03-15 2016-05-31 Mead Johnson Nutrition Company Reducing proinflammatory response
US9289461B2 (en) 2013-03-15 2016-03-22 Mead Johnson Nutrition Company Reducing the risk of autoimmune disease
CN108794570B (en) * 2018-06-15 2021-08-06 华南理工大学 Xanthine oxidase inhibitor containing phenylalanine and application thereof
WO2022125928A1 (en) * 2020-12-11 2022-06-16 Bayer Animal Health Gmbh Methods and compositions for improved production of an antigen for use in an s. aureus vaccine
EP4389865A1 (en) * 2022-12-21 2024-06-26 Novozymes A/S Recombinant protease for cell detachment

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065878A1 (en) * 2005-08-31 2007-03-22 Daugherty Patrick S Cellular libraries of peptide sequences (CLiPS) and methods of using the same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065878A1 (en) * 2005-08-31 2007-03-22 Daugherty Patrick S Cellular libraries of peptide sequences (CLiPS) and methods of using the same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOULWARE K.T. ET AL.: "Protease specificity determination by using cellular libraries of peptide substrates (CLiPS)", P.N.A.S, vol. 103, 16 August 2006 (2006-08-16), pages 7583 - 7588, XP002503593 *
DUBIN G ET AL: "Enzymatic Activity of the Staphylococcus aureus SplB Serine Protease is Induced by Substrates Containing the Sequence Trp-Glu-Leu-Gln", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 379, no. 2, 29 May 2008 (2008-05-29), pages 343 - 356, XP022648469, ISSN: 0022-2836, [retrieved on 20080403] *
POPOWICZ ET AL: "Functional and Structural Characterization of Spl Proteases from Staphylococcus aureus", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 358, no. 1, 21 April 2006 (2006-04-21), pages 270 - 279, XP005345774, ISSN: 0022-2836 *

Also Published As

Publication number Publication date
WO2008153429A2 (en) 2008-12-18

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