WO2008147245A3 - Controlled release proxodolol pharmaceutical composition - Google Patents
Controlled release proxodolol pharmaceutical composition Download PDFInfo
- Publication number
- WO2008147245A3 WO2008147245A3 PCT/RU2007/000619 RU2007000619W WO2008147245A3 WO 2008147245 A3 WO2008147245 A3 WO 2008147245A3 RU 2007000619 W RU2007000619 W RU 2007000619W WO 2008147245 A3 WO2008147245 A3 WO 2008147245A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- proxodolol
- controlled release
- pharmaceutically acceptable
- active ingredient
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
The invention relates to medicine, in particular to pharmaceutic. A novel preparation exhibiting stable kinetic characteristics relating to delivery of an active substance is disclosed. The controlled release proxodolol pharmaceutical forms can be effectively and easily produced using a mixture of one or more expanding or gel-forming components, an active ingredient and a pharmaceutically acceptable filler. In the preferred embodiment, a preparation in the form of tablets containing proxodolol in a quantity of 120 mg, hypromellose and pharmaceutically acceptable fillers, for example microcristalline cellulose, calcium stearate and aerosil, is used. The novel pharmaceutical forms with a suitable proxodolol release make it possible to reduce the number of every day medications, whilst the concentration of the active ingredient remains constant within a therapeutic dose.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2007120431/15A RU2356532C2 (en) | 2007-06-01 | 2007-06-01 | Controlled-release pharmaceutical proxodolol composition |
RU2007120431 | 2007-06-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008147245A2 WO2008147245A2 (en) | 2008-12-04 |
WO2008147245A3 true WO2008147245A3 (en) | 2009-06-04 |
Family
ID=40075688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/RU2007/000619 WO2008147245A2 (en) | 2007-06-01 | 2007-11-13 | Controlled release proxodolol pharmaceutical composition |
Country Status (2)
Country | Link |
---|---|
RU (1) | RU2356532C2 (en) |
WO (1) | WO2008147245A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103477224B (en) * | 2011-03-04 | 2015-12-23 | 贝克顿·迪金森公司 | Blood collection device containing lysophosphatide enzyme inhibitor |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996014070A1 (en) * | 1994-11-02 | 1996-05-17 | Janssen Pharmaceutica N.V. | Cisapride extended release oral compositions |
WO2000021525A2 (en) * | 1998-10-14 | 2000-04-20 | Novartis Ag | Sustained release pharmaceutical composition and method of releasing pharmaceutically active agent |
-
2007
- 2007-06-01 RU RU2007120431/15A patent/RU2356532C2/en active
- 2007-11-13 WO PCT/RU2007/000619 patent/WO2008147245A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996014070A1 (en) * | 1994-11-02 | 1996-05-17 | Janssen Pharmaceutica N.V. | Cisapride extended release oral compositions |
WO2000021525A2 (en) * | 1998-10-14 | 2000-04-20 | Novartis Ag | Sustained release pharmaceutical composition and method of releasing pharmaceutically active agent |
Also Published As
Publication number | Publication date |
---|---|
RU2007120431A (en) | 2008-12-10 |
WO2008147245A2 (en) | 2008-12-04 |
RU2356532C2 (en) | 2009-05-27 |
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