WO2008126803A1 - Ophthalmic composition comprising soluble, cross-linked hyaluronic acid - Google Patents

Ophthalmic composition comprising soluble, cross-linked hyaluronic acid Download PDF

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Publication number
WO2008126803A1
WO2008126803A1 PCT/JP2008/056806 JP2008056806W WO2008126803A1 WO 2008126803 A1 WO2008126803 A1 WO 2008126803A1 JP 2008056806 W JP2008056806 W JP 2008056806W WO 2008126803 A1 WO2008126803 A1 WO 2008126803A1
Authority
WO
WIPO (PCT)
Prior art keywords
soluble
cross
hyaluronic acid
ophthalmic composition
linked hyaluronic
Prior art date
Application number
PCT/JP2008/056806
Other languages
French (fr)
Japanese (ja)
Inventor
Osamu Ueda
Rakan Matsui
Takeo Obara
Masami Ishida
Original Assignee
Shiseido Company, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Company, Ltd. filed Critical Shiseido Company, Ltd.
Publication of WO2008126803A1 publication Critical patent/WO2008126803A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Abstract

Disclosed is an ophthalmic composition comprising a soluble, cross-linked hyaluronic acid and a pharmaceutically acceptable carrier.
PCT/JP2008/056806 2007-04-06 2008-04-04 Ophthalmic composition comprising soluble, cross-linked hyaluronic acid WO2008126803A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007100561A JP2008255061A (en) 2007-04-06 2007-04-06 Soluble cross-linked hyaluronic acid-containing ophthalmic composition
JP2007-100561 2007-04-06

Publications (1)

Publication Number Publication Date
WO2008126803A1 true WO2008126803A1 (en) 2008-10-23

Family

ID=39863901

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/056806 WO2008126803A1 (en) 2007-04-06 2008-04-04 Ophthalmic composition comprising soluble, cross-linked hyaluronic acid

Country Status (2)

Country Link
JP (1) JP2008255061A (en)
WO (1) WO2008126803A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013021249A1 (en) * 2011-08-10 2013-02-14 Glycores 2000 S.R.L. Degradation-resistant cross-linked, low-molecular-weight hyaluronate
WO2016104705A1 (en) * 2014-12-26 2016-06-30 生化学工業株式会社 Agent and method for improving subjective symptoms in eyes
WO2018069763A1 (en) * 2016-10-14 2018-04-19 i.com medical GmbH Method for establishing, restoring, and preserving homeostasis of the ocular surface

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2068365A3 (en) 2007-12-04 2009-08-19 Nissan Motor Co., Ltd. Semiconductor device

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60233101A (en) * 1984-05-04 1985-11-19 Seikagaku Kogyo Co Ltd Crosslinked hyaluronic acid
JPS61172808A (en) * 1985-01-29 1986-08-04 Seikagaku Kogyo Co Ltd Skin cosmetic
JPS61502310A (en) * 1984-06-08 1986-10-16 カビ・フアーマシア・アー・ベー Vitreous humor substitute consisting of cross-linked hyaluronic acid gel
JPS62129226A (en) * 1985-11-29 1987-06-11 バイオマトリツクス、インコ−ポレ−テツド Drug release system depending on hyaluronane, derivatives ortheir salts and manufacture
JPH01238530A (en) * 1988-03-17 1989-09-22 Seikagaku Kogyo Co Ltd Remedy for cornea anterior epithelium layer injury
JP2002529550A (en) * 1998-11-11 2002-09-10 アクイジティオ ソチエタ ペル アツィオニ Crosslinked hyaluronic acid and its medical use
JP2006111867A (en) * 2004-09-15 2006-04-27 Seikagaku Kogyo Co Ltd Photoreactive polysaccharide, its photocrosslinking polysaccharide product, and medical material
WO2006056204A1 (en) * 2004-11-24 2006-06-01 Novozymes Biopolymer A/S Method of cross-linking hyaluronic acid with divinylsulfone
JP2006523731A (en) * 2003-04-17 2006-10-19 ウルトラシューティカルズ アールアンドディー ピーティーワイ リミテッド Cross-linked polysaccharide composition

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60233101A (en) * 1984-05-04 1985-11-19 Seikagaku Kogyo Co Ltd Crosslinked hyaluronic acid
JPS61502310A (en) * 1984-06-08 1986-10-16 カビ・フアーマシア・アー・ベー Vitreous humor substitute consisting of cross-linked hyaluronic acid gel
JPS61172808A (en) * 1985-01-29 1986-08-04 Seikagaku Kogyo Co Ltd Skin cosmetic
JPS62129226A (en) * 1985-11-29 1987-06-11 バイオマトリツクス、インコ−ポレ−テツド Drug release system depending on hyaluronane, derivatives ortheir salts and manufacture
JPH01238530A (en) * 1988-03-17 1989-09-22 Seikagaku Kogyo Co Ltd Remedy for cornea anterior epithelium layer injury
JP2002529550A (en) * 1998-11-11 2002-09-10 アクイジティオ ソチエタ ペル アツィオニ Crosslinked hyaluronic acid and its medical use
JP2006523731A (en) * 2003-04-17 2006-10-19 ウルトラシューティカルズ アールアンドディー ピーティーワイ リミテッド Cross-linked polysaccharide composition
JP2006111867A (en) * 2004-09-15 2006-04-27 Seikagaku Kogyo Co Ltd Photoreactive polysaccharide, its photocrosslinking polysaccharide product, and medical material
WO2006056204A1 (en) * 2004-11-24 2006-06-01 Novozymes Biopolymer A/S Method of cross-linking hyaluronic acid with divinylsulfone

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MALSON T. ET AL.: "Crosslinked hyaluronate gels for use un vitreous surgery", ADVANCES IN BIOMATERIALS (BIOMATER. CLIN. APPL.), vol. 7, 1987, pages 345 - 348, XP001034875 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013021249A1 (en) * 2011-08-10 2013-02-14 Glycores 2000 S.R.L. Degradation-resistant cross-linked, low-molecular-weight hyaluronate
RU2613887C2 (en) * 2011-08-10 2017-03-21 Гликорес 2000 С.Р.Л. Split-resistant low molecular cross-linked hyaluronate
WO2016104705A1 (en) * 2014-12-26 2016-06-30 生化学工業株式会社 Agent and method for improving subjective symptoms in eyes
US11147831B2 (en) 2014-12-26 2021-10-19 Seikagaku Corporation Agent for improving ocular subjective symptoms and method thereof
US11185558B2 (en) 2014-12-26 2021-11-30 Seikagaku Corporation Agent for improving ocular subjective symptoms and method thereof
US11779593B2 (en) 2014-12-26 2023-10-10 Seikagaku Corporation Agent for improving ocular subjective symptoms and method thereof
WO2018069763A1 (en) * 2016-10-14 2018-04-19 i.com medical GmbH Method for establishing, restoring, and preserving homeostasis of the ocular surface
JP2019532105A (en) * 2016-10-14 2019-11-07 アイ．コム メディカル ゲーエムベーハー Methods for establishing, restoring and maintaining keratoconjunctival homeostasis
EP3871682A1 (en) * 2016-10-14 2021-09-01 i.com Medical GmbH Method for establishing, restoring, and preserving homeostasis of the ocular surface
JP2022153583A (en) * 2016-10-14 2022-10-12 アイ．コム メディカル ゲーエムベーハー Method for establishing, restoring and preserving homeostasis of ocular surface

Also Published As

Publication number Publication date
JP2008255061A (en) 2008-10-23

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