WO2008119146A3 - Combi-preparation of phosphoethanolamine and omega-3-fatty acid for treating bronchial asthma and copd - Google Patents

Combi-preparation of phosphoethanolamine and omega-3-fatty acid for treating bronchial asthma and copd Download PDF

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Publication number
WO2008119146A3
WO2008119146A3 PCT/BR2008/000093 BR2008000093W WO2008119146A3 WO 2008119146 A3 WO2008119146 A3 WO 2008119146A3 BR 2008000093 W BR2008000093 W BR 2008000093W WO 2008119146 A3 WO2008119146 A3 WO 2008119146A3
Authority
WO
WIPO (PCT)
Prior art keywords
phosphoethanolamine
day
omega
bronchial asthma
combi
Prior art date
Application number
PCT/BR2008/000093
Other languages
French (fr)
Other versions
WO2008119146A8 (en
WO2008119146A2 (en
Original Assignee
Dair Bicudo Piai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dair Bicudo Piai filed Critical Dair Bicudo Piai
Priority to PCT/BR2008/000093 priority Critical patent/WO2008119146A2/en
Publication of WO2008119146A2 publication Critical patent/WO2008119146A2/en
Publication of WO2008119146A3 publication Critical patent/WO2008119146A3/en
Publication of WO2008119146A8 publication Critical patent/WO2008119146A8/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The object of the invention is a composition for the treatment of bronchial asthma and chronic obstructive pulmonary disease, characterized in that the composition comprises phosphoethanolamine and Omega-3 folly acids in pre-established proportions. The preferred dose is 400 to 1200 mg/day, more specifically 800 mg/day for the phosphoethanolamine and 500 to 3200 mg/day, more specifically 1000 mg/day for the cicosapentaenoic acid 'EPA' and 350 to 2000 mg/day, more specifically 750 mg/day for the cocosahexaenoic acid 'DHA'.
PCT/BR2008/000093 2007-03-29 2008-03-31 Combi-preparation of phosphoethanolamine and omega-3-fatty acid for treating bronchial asthma and copd WO2008119146A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/BR2008/000093 WO2008119146A2 (en) 2007-03-29 2008-03-31 Combi-preparation of phosphoethanolamine and omega-3-fatty acid for treating bronchial asthma and copd

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0701374-4 2007-03-29
PCT/BR2008/000093 WO2008119146A2 (en) 2007-03-29 2008-03-31 Combi-preparation of phosphoethanolamine and omega-3-fatty acid for treating bronchial asthma and copd

Publications (3)

Publication Number Publication Date
WO2008119146A2 WO2008119146A2 (en) 2008-10-09
WO2008119146A3 true WO2008119146A3 (en) 2008-12-18
WO2008119146A8 WO2008119146A8 (en) 2010-02-18

Family

ID=41678990

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2008/000093 WO2008119146A2 (en) 2007-03-29 2008-03-31 Combi-preparation of phosphoethanolamine and omega-3-fatty acid for treating bronchial asthma and copd

Country Status (1)

Country Link
WO (1) WO2008119146A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102016008247A2 (en) * 2016-04-13 2017-10-17 Acolli S.A. FOOD SUPPLEMENT BASED ON 2-AMINOETHANOL DIHYDROGENOPHOSPHATE AND SYNTHESIS PROCESS
WO2024073678A2 (en) * 2022-09-30 2024-04-04 Omega Therapeutics, Inc. Phospholipids containing a heterocycle ring having a tertiary amine or amide

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021912A1 (en) * 1992-04-28 1993-11-11 Fresenius Ag Use of an emulsion containing omega-3 fatty acids to produce a medicament to be parenterally administered for treating inflammatory diseases
WO2004064716A2 (en) * 2003-01-24 2004-08-05 Pabay Investments Limited Eicosapentaenoic acid and docosapentaenoic acid for treating inflammatory disorders
US20050080052A1 (en) * 1998-11-26 2005-04-14 Britannia Pharmaceuticals Limited Anti-asthmatic combinations comprising surface active phospholipids
WO2005089744A2 (en) * 2004-03-17 2005-09-29 The Brigham And Women's Hospital, Inc. Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
WO2007026071A1 (en) * 2005-09-01 2007-03-08 Pieroni Gerard Use of dha in the form of phospholipids for the preparation of a composition that is intended for the treatment of respiratory failure

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021912A1 (en) * 1992-04-28 1993-11-11 Fresenius Ag Use of an emulsion containing omega-3 fatty acids to produce a medicament to be parenterally administered for treating inflammatory diseases
US20050080052A1 (en) * 1998-11-26 2005-04-14 Britannia Pharmaceuticals Limited Anti-asthmatic combinations comprising surface active phospholipids
WO2004064716A2 (en) * 2003-01-24 2004-08-05 Pabay Investments Limited Eicosapentaenoic acid and docosapentaenoic acid for treating inflammatory disorders
WO2005089744A2 (en) * 2004-03-17 2005-09-29 The Brigham And Women's Hospital, Inc. Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
WO2007026071A1 (en) * 2005-09-01 2007-03-08 Pieroni Gerard Use of dha in the form of phospholipids for the preparation of a composition that is intended for the treatment of respiratory failure

Also Published As

Publication number Publication date
WO2008119146A8 (en) 2010-02-18
WO2008119146A2 (en) 2008-10-09

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