WO2008098109A3 - Hydrogel compositions - Google Patents

Hydrogel compositions Download PDF

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Publication number
WO2008098109A3
WO2008098109A3 PCT/US2008/053287 US2008053287W WO2008098109A3 WO 2008098109 A3 WO2008098109 A3 WO 2008098109A3 US 2008053287 W US2008053287 W US 2008053287W WO 2008098109 A3 WO2008098109 A3 WO 2008098109A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydrogels
hydrogel compositions
making
compositions
vitro
Prior art date
Application number
PCT/US2008/053287
Other languages
French (fr)
Other versions
WO2008098109A2 (en
WO2008098109A9 (en
Inventor
Lonnie D Shea
Teresa Woodruff
Original Assignee
Univ Northwestern
Lonnie D Shea
Teresa Woodruff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Northwestern, Lonnie D Shea, Teresa Woodruff filed Critical Univ Northwestern
Publication of WO2008098109A2 publication Critical patent/WO2008098109A2/en
Publication of WO2008098109A3 publication Critical patent/WO2008098109A3/en
Publication of WO2008098109A9 publication Critical patent/WO2008098109A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/28—Treatment by wave energy or particle radiation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

The invention provides compositions for making hydrogels with improved mechanical properties, particularly for biological cultures. It provides methods for making the hydrogels and for using them. Exemplary hydrogels are made from irradiated or oxidized alginate compositions. Such hydrogels are useful for, especially, culturing follicles in vitro.
PCT/US2008/053287 2007-02-08 2008-02-07 Hydrogel compositions WO2008098109A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90024107P 2007-02-08 2007-02-08
US60/900,241 2007-02-08

Publications (3)

Publication Number Publication Date
WO2008098109A2 WO2008098109A2 (en) 2008-08-14
WO2008098109A3 true WO2008098109A3 (en) 2008-10-30
WO2008098109A9 WO2008098109A9 (en) 2008-12-11

Family

ID=39643422

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/053287 WO2008098109A2 (en) 2007-02-08 2008-02-07 Hydrogel compositions

Country Status (1)

Country Link
WO (1) WO2008098109A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL187707A0 (en) 2007-11-27 2008-11-03 Univ Ben Gurion Alginate scaffold in hepatectomy
JP6046644B2 (en) * 2011-03-04 2016-12-21 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ Encapsulated cells for hormone replacement therapy
CA2919255C (en) 2013-09-03 2022-05-17 Wake Forest University Health Sciences Encapsulated cells for hormone replacement therapy
WO2015172073A1 (en) 2014-05-08 2015-11-12 Cornell University Bio-adhesive gels and methods of use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012228A1 (en) * 1996-09-19 1998-03-26 The Regents Of The University Of Michigan Polymers containing polysaccharides such as alginates or modified alginates

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012228A1 (en) * 1996-09-19 1998-03-26 The Regents Of The University Of Michigan Polymers containing polysaccharides such as alginates or modified alginates

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BIOMACROMOLECULES, vol. 5, no. 5, 2004, pages 1720 - 1727 *
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KONG, HYUN JOON ET AL.: "Controlling rigidity and degradation of alginate hydrogels via molecular weight distribution", XP002493437, retrieved from STN Database accession no. 2004:552251 *
KONG H J ET AL: "Designing alginate hydrogels to maintain viability of immobilized cells", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 24, no. 22, 1 October 2003 (2003-10-01), pages 4023 - 4029, XP004434244, ISSN: 0142-9612 *
KONG H-J ET AL: "Decoupling the dependence of rheological/mechanical properties of hydrogels from solids concentration", POLYMER, ELSEVIER SCIENCE PUBLISHERS B.V, GB, vol. 43, no. 23, 1 January 2002 (2002-01-01), pages 6239 - 6246, XP004383568, ISSN: 0032-3861 *
KREEGER ET AL: "The in vitro regulation of ovarian follicle development using alginate-extracellular matrix gels", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 27, no. 5, 1 February 2006 (2006-02-01), pages 714 - 723, XP005124202, ISSN: 0142-9612 *

Also Published As

Publication number Publication date
WO2008098109A2 (en) 2008-08-14
WO2008098109A9 (en) 2008-12-11

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