WO2008095603A3 - Farbmarkierte oligo- oder polysaccharide - Google Patents

Farbmarkierte oligo- oder polysaccharide Download PDF

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Publication number
WO2008095603A3
WO2008095603A3 PCT/EP2008/000479 EP2008000479W WO2008095603A3 WO 2008095603 A3 WO2008095603 A3 WO 2008095603A3 EP 2008000479 W EP2008000479 W EP 2008000479W WO 2008095603 A3 WO2008095603 A3 WO 2008095603A3
Authority
WO
WIPO (PCT)
Prior art keywords
polysaccharides
color
oligosaccharides
marked
marked oligosaccharides
Prior art date
Application number
PCT/EP2008/000479
Other languages
English (en)
French (fr)
Other versions
WO2008095603A2 (de
Inventor
Joerg Kowalczyk
Thomas Rose
Stephan Hausmanns
Thomas Walter
Wolfgang Wach
Norbert Gretz
Maliha Sadick
Daniel Schock
Original Assignee
Suedzucker Ag
Joerg Kowalczyk
Thomas Rose
Stephan Hausmanns
Thomas Walter
Wolfgang Wach
Norbert Gretz
Maliha Sadick
Daniel Schock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suedzucker Ag, Joerg Kowalczyk, Thomas Rose, Stephan Hausmanns, Thomas Walter, Wolfgang Wach, Norbert Gretz, Maliha Sadick, Daniel Schock filed Critical Suedzucker Ag
Priority to AU2008213452A priority Critical patent/AU2008213452B2/en
Priority to EP08707201A priority patent/EP2121033A2/de
Priority to CA002677686A priority patent/CA2677686A1/en
Priority to US12/525,992 priority patent/US20100008860A1/en
Priority to JP2009548599A priority patent/JP2010518034A/ja
Publication of WO2008095603A2 publication Critical patent/WO2008095603A2/de
Publication of WO2008095603A3 publication Critical patent/WO2008095603A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052—Small organic molecules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Die Erfindung betrifft farbmarkierte Oligo- oder Polysaccharide, Verfahren zur Herstellung dieser farbmarkierten Oligo- oder Polysaccharide und ihre Verwendung zur Nierenfunktionsbestimmung.
PCT/EP2008/000479 2007-02-09 2008-01-23 Farbmarkierte oligo- oder polysaccharide WO2008095603A2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2008213452A AU2008213452B2 (en) 2007-02-09 2008-01-23 Color-marked oligosaccharides or polysaccharides
EP08707201A EP2121033A2 (de) 2007-02-09 2008-01-23 Farbmarkierte oligo- oder polysaccharide
CA002677686A CA2677686A1 (en) 2007-02-09 2008-01-23 Color-marked oligosaccharides or polysaccharides
US12/525,992 US20100008860A1 (en) 2007-02-09 2008-01-23 Color-marked oligosaccharides or polysaccharides
JP2009548599A JP2010518034A (ja) 2007-02-09 2008-01-23 色標識オリゴ糖又は多糖

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007007738A DE102007007738A1 (de) 2007-02-09 2007-02-09 Farbmarkierte Oligo- oder Polysaccharide
DE102007007738.8 2007-02-09

Publications (2)

Publication Number Publication Date
WO2008095603A2 WO2008095603A2 (de) 2008-08-14
WO2008095603A3 true WO2008095603A3 (de) 2009-04-16

Family

ID=39591140

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/000479 WO2008095603A2 (de) 2007-02-09 2008-01-23 Farbmarkierte oligo- oder polysaccharide

Country Status (7)

Country Link
US (1) US20100008860A1 (de)
EP (1) EP2121033A2 (de)
JP (1) JP2010518034A (de)
AU (1) AU2008213452B2 (de)
CA (1) CA2677686A1 (de)
DE (1) DE102007007738A1 (de)
WO (1) WO2008095603A2 (de)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040106A1 (en) * 1997-03-13 1998-09-17 Mallinckrodt Inc. Method of measuring physiological function
WO2002032285A2 (en) * 2000-10-16 2002-04-25 Mallinckrodt Inc. Hydrophilic light absorbing compositions for determination of physiological function in critically ill patients
US6423547B1 (en) * 1998-04-03 2002-07-23 Mallinckrodt Inc. Non-covalent bioconjugates useful for diagnosis and therapy
EP1604689A1 (de) * 2000-03-06 2005-12-14 Mallinckrodt, Inc. Gleichzeitiger multimodale Messung von physiologischen Funktionen
WO2006032441A2 (de) * 2004-09-21 2006-03-30 Roche Diagnostics Gmbh Stöchiometrisch definierte farbstoffmarkierte substanzen zur messung der glomerulären filtrationsrate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466471A (en) * 1994-07-18 1995-11-14 Wm. Wrigley Jr. Company Chewing gum containing aspartame and maltodextrin or purified maltodextrin
US6228344B1 (en) * 1997-03-13 2001-05-08 Mallinckrodt Inc. Method of measuring physiological function
DE10023051B4 (de) 2000-05-11 2004-02-19 Roche Diagnostics Gmbh Verfahren zur Herstellung von Fluoresceinisothiocyanat-Sinistrin, dessen Verwendung und Fluoresceinisothiocyanat-Sinistrin enthaltende diagnostische Zubereitung
TWI312369B (en) * 2000-08-01 2009-07-21 Hayashibara Biochem Lab A-isomaltosylglucosaccharide synthase,process for producing the same and use thereof
DK1470163T3 (da) * 2002-01-30 2006-05-15 Sigma Coatings Bv Polysaccharidestere og anvendelser deraf som bindemidler i overtræk

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040106A1 (en) * 1997-03-13 1998-09-17 Mallinckrodt Inc. Method of measuring physiological function
US6423547B1 (en) * 1998-04-03 2002-07-23 Mallinckrodt Inc. Non-covalent bioconjugates useful for diagnosis and therapy
EP1604689A1 (de) * 2000-03-06 2005-12-14 Mallinckrodt, Inc. Gleichzeitiger multimodale Messung von physiologischen Funktionen
WO2002032285A2 (en) * 2000-10-16 2002-04-25 Mallinckrodt Inc. Hydrophilic light absorbing compositions for determination of physiological function in critically ill patients
WO2006032441A2 (de) * 2004-09-21 2006-03-30 Roche Diagnostics Gmbh Stöchiometrisch definierte farbstoffmarkierte substanzen zur messung der glomerulären filtrationsrate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
H.H. SCHLUBACH UND H.O.A. KOEHN: "DIE BILDUNG DER VERZWEIGTEN POLYFRUCTOSANE IN DEN ROGGENHALMEN", LIEBIGS ANN. CHEM. BD., vol. 614, 1958, pages 126 - 136, XP007906971 *

Also Published As

Publication number Publication date
EP2121033A2 (de) 2009-11-25
US20100008860A1 (en) 2010-01-14
AU2008213452B2 (en) 2012-09-27
AU2008213452A1 (en) 2008-08-14
WO2008095603A2 (de) 2008-08-14
DE102007007738A1 (de) 2008-08-14
JP2010518034A (ja) 2010-05-27
CA2677686A1 (en) 2008-07-14

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