WO2008094507A3 - Novel fusion compounds - Google Patents

Novel fusion compounds Download PDF

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Publication number
WO2008094507A3
WO2008094507A3 PCT/US2008/001092 US2008001092W WO2008094507A3 WO 2008094507 A3 WO2008094507 A3 WO 2008094507A3 US 2008001092 W US2008001092 W US 2008001092W WO 2008094507 A3 WO2008094507 A3 WO 2008094507A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel fusion
fusion compounds
compounds
compositions
management
Prior art date
Application number
PCT/US2008/001092
Other languages
French (fr)
Other versions
WO2008094507A2 (en
Inventor
Tsvetelina Lazarova
Michael Thormann
Michael Almstetter
Guillaume Cottarel
Steven Wayne Riesinger
Original Assignee
Cellicon Biotechnologies Inc
Tsvetelina Lazarova
Michael Thormann
Michael Almstetter
Guillaume Cottarel
Steven Wayne Riesinger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellicon Biotechnologies Inc, Tsvetelina Lazarova, Michael Thormann, Michael Almstetter, Guillaume Cottarel, Steven Wayne Riesinger filed Critical Cellicon Biotechnologies Inc
Publication of WO2008094507A2 publication Critical patent/WO2008094507A2/en
Publication of WO2008094507A3 publication Critical patent/WO2008094507A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/46—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with acyclic hydrocarbon radicals or such radicals substituted by carbocyclic or heterocyclic rings, attached to the carboxamido radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to novel compounds derived from compounds having antibiotic activities. The invention further provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by anti-infective agents, particularly those relating to the management of bacterial infection.
PCT/US2008/001092 2007-01-26 2008-01-25 Novel fusion compounds WO2008094507A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89798107P 2007-01-26 2007-01-26
US60/897,981 2007-01-26

Publications (2)

Publication Number Publication Date
WO2008094507A2 WO2008094507A2 (en) 2008-08-07
WO2008094507A3 true WO2008094507A3 (en) 2008-10-02

Family

ID=39674685

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/001092 WO2008094507A2 (en) 2007-01-26 2008-01-25 Novel fusion compounds

Country Status (1)

Country Link
WO (1) WO2008094507A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393250B2 (en) 2012-04-12 2016-07-19 University Of Saskatchewan Phthalocyanine compounds useful as RecA inhibitors and methods of using same
MX2015011948A (en) 2013-03-08 2015-12-09 Allergan Inc Antibiotic conjugates directly linked with steroid drugs.
SG11201507241UA (en) 2013-03-08 2015-10-29 Allergan Inc Cyclosporine a-steroid conjugates
MA44037B1 (en) 2016-06-06 2020-03-31 Arena Pharm Inc Beta 3 adrenergic receptor modulators useful in the treatment or prevention of disorders associated therewith
CN106565654B (en) * 2016-10-14 2018-08-31 云南中烟工业有限责任公司 A kind of novel flavone compound, Its Preparation Method And Use extracted from Bai Yun Shen
CR20220316A (en) 2019-12-06 2022-10-07 Vertex Pharma Substituted tetrahydrofurans as modulators of sodium channels
AU2021244718A1 (en) * 2020-03-23 2022-11-03 John M.H. GREGG Anti-viral compounds and methods for administration thereof
CN117794920A (en) 2021-06-04 2024-03-29 沃泰克斯药物股份有限公司 N- (hydroxyalkyl (hetero) aryl) tetrahydrofurancarboxamides as sodium channel modulators
CN114315812A (en) * 2021-12-31 2022-04-12 广西师范大学 Two alkaloid compounds derived from marine fungi, and their preparation methods and application in preparing antiinflammatory medicine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050119269A1 (en) * 2003-10-28 2005-06-02 Rao Yeleswarapu K. Heterocyclic compounds and methods of making and using thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050119269A1 (en) * 2003-10-28 2005-06-02 Rao Yeleswarapu K. Heterocyclic compounds and methods of making and using thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DA SILVA ET AL.: "Biological Activity and Synthetic Metodologies for the Preparation of Fluoroquinolones, A Class of Potent Antibacterial Agents", CURRENT MEDICINAL CHEMISTRY, vol. 10, 2003, pages 21 - 39 *

Also Published As

Publication number Publication date
WO2008094507A2 (en) 2008-08-07

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