WO2008093358A3 - Aqueous topical solution containing olopatadine - Google Patents

Aqueous topical solution containing olopatadine Download PDF

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Publication number
WO2008093358A3
WO2008093358A3 PCT/IN2008/000054 IN2008000054W WO2008093358A3 WO 2008093358 A3 WO2008093358 A3 WO 2008093358A3 IN 2008000054 W IN2008000054 W IN 2008000054W WO 2008093358 A3 WO2008093358 A3 WO 2008093358A3
Authority
WO
WIPO (PCT)
Prior art keywords
topical solution
aqueous topical
solution containing
olopatadine
containing olopatadine
Prior art date
Application number
PCT/IN2008/000054
Other languages
French (fr)
Other versions
WO2008093358A2 (en
Inventor
Subhas Balaram Bhowmick
Ritu Nitin Laddha
Original Assignee
Sun Pharmaceutical Ind Ltd
Subhas Balaram Bhowmick
Ritu Nitin Laddha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Ind Ltd, Subhas Balaram Bhowmick, Ritu Nitin Laddha filed Critical Sun Pharmaceutical Ind Ltd
Publication of WO2008093358A2 publication Critical patent/WO2008093358A2/en
Publication of WO2008093358A3 publication Critical patent/WO2008093358A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to an aqueous topical solution comprising a therapeutically active ingredient consisting essentially of olopatadine or its pharmaceutically acceptable salt and a solubilizer selected from a group consisting of tyloxapol, vitamin E tocopheryl polyethylene glycol diesters of dicarboxylic acids and mixtures thereof, wherein the aqueous topical solution is stable.
PCT/IN2008/000054 2007-01-29 2008-01-29 Aqueous topical solution containing olopatadine WO2008093358A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN159/MUM/2007 2007-01-29
IN159MU2007 2007-01-29

Publications (2)

Publication Number Publication Date
WO2008093358A2 WO2008093358A2 (en) 2008-08-07
WO2008093358A3 true WO2008093358A3 (en) 2008-10-16

Family

ID=39674597

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2008/000054 WO2008093358A2 (en) 2007-01-29 2008-01-29 Aqueous topical solution containing olopatadine

Country Status (1)

Country Link
WO (1) WO2008093358A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2189157A4 (en) * 2007-09-06 2012-10-31 Kyowa Hakko Kirin Co Ltd EYE DROP COMPRISING DIBENZO[b,e]OXEPIN DERIVATIVE
CN102548536A (en) * 2009-10-01 2012-07-04 爱尔康研究有限公司 Olopatadine compositions and uses thereof
CN109254102B (en) * 2017-07-14 2022-02-15 上海联陆实业股份有限公司 High performance liquid detection method for water-soluble vitamin E derivatives

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030055102A1 (en) * 2001-06-27 2003-03-20 Alcon, Inc. Olopatadine formulations for topical administration
US6743439B1 (en) * 2001-06-27 2004-06-01 Alcon, Inc. Ophthalmic compositions containing copolymers of sulfonated styrene and maleic anhydride
WO2005020962A1 (en) * 2003-08-29 2005-03-10 Novagali Pharma Sa Self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs
US20050209312A1 (en) * 2004-03-19 2005-09-22 Bausch & Lomb Incorporated Carboxylic acid derivatives of doxepin formulations preserved with low-irritation preservative
WO2006036614A2 (en) * 2004-09-24 2006-04-06 Boehringer Ingelheim Pharmaceuticals, Inc. A new class of surfactant-like materials comprising vitamin e tpgs and a water soluble polymer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030055102A1 (en) * 2001-06-27 2003-03-20 Alcon, Inc. Olopatadine formulations for topical administration
US6743439B1 (en) * 2001-06-27 2004-06-01 Alcon, Inc. Ophthalmic compositions containing copolymers of sulfonated styrene and maleic anhydride
WO2005020962A1 (en) * 2003-08-29 2005-03-10 Novagali Pharma Sa Self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs
US20050209312A1 (en) * 2004-03-19 2005-09-22 Bausch & Lomb Incorporated Carboxylic acid derivatives of doxepin formulations preserved with low-irritation preservative
WO2006036614A2 (en) * 2004-09-24 2006-04-06 Boehringer Ingelheim Pharmaceuticals, Inc. A new class of surfactant-like materials comprising vitamin e tpgs and a water soluble polymer

Also Published As

Publication number Publication date
WO2008093358A2 (en) 2008-08-07

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