WO2008090831A1 - 酵素組成物及びその用途 - Google Patents

酵素組成物及びその用途 Download PDF

Info

Publication number
WO2008090831A1
WO2008090831A1 PCT/JP2008/050673 JP2008050673W WO2008090831A1 WO 2008090831 A1 WO2008090831 A1 WO 2008090831A1 JP 2008050673 W JP2008050673 W JP 2008050673W WO 2008090831 A1 WO2008090831 A1 WO 2008090831A1
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme composition
prevention
treatment
inflammatory bowel
bowel disease
Prior art date
Application number
PCT/JP2008/050673
Other languages
English (en)
French (fr)
Inventor
Takashi Joh
Makoto Sasaki
Satoshi Koikeda
Original Assignee
Amano Enzyme Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amano Enzyme Inc. filed Critical Amano Enzyme Inc.
Priority to JP2008555041A priority Critical patent/JP5627184B2/ja
Priority to CN200880001606XA priority patent/CN101594879B/zh
Priority to AT08703523T priority patent/ATE520413T1/de
Priority to EP08703523A priority patent/EP2127668B1/en
Priority to US12/449,007 priority patent/US20110150855A1/en
Publication of WO2008090831A1 publication Critical patent/WO2008090831A1/ja

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • C12N9/1055Levansucrase (2.4.1.10)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

 炎症性腸疾患の治療又は予防に有効な手段を提供することを課題とする。生体内でオリゴ糖を生成する能力を有する酵素を用いた、炎症性腸疾患の治療又は予防用の酵素組成物が提供される。
PCT/JP2008/050673 2007-01-26 2008-01-21 酵素組成物及びその用途 WO2008090831A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2008555041A JP5627184B2 (ja) 2007-01-26 2008-01-21 酵素組成物及びその用途
CN200880001606XA CN101594879B (zh) 2007-01-26 2008-01-21 酶组合物及其用途
AT08703523T ATE520413T1 (de) 2007-01-26 2008-01-21 Glycosyltransferase zur behandlung von entzündlichen darmkrankheiten
EP08703523A EP2127668B1 (en) 2007-01-26 2008-01-21 Glycosyltransferase for treating Inflammatory Bowel Disease
US12/449,007 US20110150855A1 (en) 2007-01-26 2008-01-21 Enzyme Composition and Use Thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007016892 2007-01-26
JP2007-016892 2007-01-26

Publications (1)

Publication Number Publication Date
WO2008090831A1 true WO2008090831A1 (ja) 2008-07-31

Family

ID=39644408

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/050673 WO2008090831A1 (ja) 2007-01-26 2008-01-21 酵素組成物及びその用途

Country Status (6)

Country Link
US (1) US20110150855A1 (ja)
EP (1) EP2127668B1 (ja)
JP (1) JP5627184B2 (ja)
CN (1) CN101594879B (ja)
AT (1) ATE520413T1 (ja)
WO (1) WO2008090831A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3927180A1 (en) * 2019-02-19 2021-12-29 DSM IP Assets B.V. Method for reducing fructan in a food product with aid of invertase (ec 3.2.1.26)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03183457A (ja) * 1989-12-11 1991-08-09 Advance Co Ltd 機能性食品
JP2000325045A (ja) 1998-07-02 2000-11-28 Amano Pharmaceut Co Ltd 酵素組成物及びその用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0229015D0 (en) * 2002-12-12 2003-01-15 Novartis Nutrition Ag New Compound

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03183457A (ja) * 1989-12-11 1991-08-09 Advance Co Ltd 機能性食品
JP2000325045A (ja) 1998-07-02 2000-11-28 Amano Pharmaceut Co Ltd 酵素組成物及びその用途

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CHERBUT C. ET AL.: "The prebiotic characteristics of fructooligosaccharides are necessary for reduction of TNBS-induced colitis in rats", JOURNAL OF NUTRITION, vol. 133, no. 1, 2003, pages 21 - 27, XP008110893 *
DADDAOUA A. ET AL.: "Goat milk oligosaccharides are anti-inflammatory in rats with hapten-induced colitis", JOURNAL OF NUTRITION, vol. 136, no. 3, 2006, pages 672 - 676, XP008110892 *
DENPUN KAGAKU, vol. 38, no. 2, 1991, pages 217 - 222
JOURNAL OF FERMENTATION AND BIOENGINEERING, vol. 79, no. 4, 1995, pages 367 - 369
K. L. MADSEN ET AL.: "Lactobacillus species prevents colitis in interleukin 10-gene-deficient mice", GASTROENTEROLOGY, vol. 116, 1999, pages 1107 - 1114, XP008023587, DOI: doi:10.1016/S0016-5085(99)70013-2
RUMI G. ET AL.: "Protective effect of lactulose on dextran sulfate sodium-induced colonic inflammation in rats", DIGESTIVE DISEASES AND SCIENCES, vol. 49, no. 9, 2004, pages 1466 - 1472, XP008110897 *
SASAKI M ET AL., J PHARMACOL EXP THER, vol. 305, no. 1, 2003, pages 78 - 85
SASAKI M ET AL., J PHARMACOL EXP THER., vol. 305, no. 1, 2003, pages 78 - 85
WINKLER J. ET AL.: "Fructo-oligosaccharide reduces inflammation in a dextran sodium sulphate mouse model of colitis", DIGESTIVE DISEASES AND SCIENCES, vol. 52, no. 1, 14 December 2006 (2006-12-14), pages 52 - 58, XP019464741, Retrieved from the Internet <URL:http://www.springerlink.com/content/f13046123m150w6u/fulltext.pdf> *

Also Published As

Publication number Publication date
US20110150855A1 (en) 2011-06-23
JPWO2008090831A1 (ja) 2010-05-20
CN101594879A (zh) 2009-12-02
EP2127668A1 (en) 2009-12-02
CN101594879B (zh) 2012-06-20
EP2127668B1 (en) 2011-08-17
ATE520413T1 (de) 2011-09-15
EP2127668A4 (en) 2010-05-12
JP5627184B2 (ja) 2014-11-19

Similar Documents

Publication Publication Date Title
EP2369017B8 (en) Micro-RNA-based methods and compositions for the diagnosis and treatment of colon related diseases
IL233634A0 (en) Methods, compositions and kits for treating medical conditions
WO2007007173A3 (en) Human anti-madcam antibodies
HK1132302A1 (en) Micrornarna-based methods and compositions for the diagnosis and treatment of solid cancers rna
AU2007243282A8 (en) Compositions and methods for the treatment of cardiovascular disease
EP1843781A4 (en) COMPOSITION FOR THE PREVENTION, TREATMENT AND DIAGNOSIS OF INFLAMMATORY CHRONIC DISEASES OF AIRWAYS
GB0620695D0 (en) Composition and methods for the treatment of nurdegenerative disease
WO2008090831A1 (ja) 酵素組成物及びその用途
AU2006901699A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease I
AU2006902538A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease XXXII
AU2006901704A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease VI
AU2006902532A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease XVII
AU2006901703A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease V
AU2006901700A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease II
AU2006902536A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease XXX
AU2005905424A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease I
AU2006902524A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease IX
AU2006902527A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease XI
AU2006902537A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease XXXI
GB0615888D0 (en) Modification of enzymatic action for the treatment of microbes or disease
AU2006901701A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease III
AU2006902525A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease X
AU2006905090A0 (en) Methods and compositions for the diagnosis and treatment of tumours
AU2006901706A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease VIII
AU2006902533A0 (en) Diagnosis, prognosis and treatment of neurodegenerative disease XVIII

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880001606.X

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08703523

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2008555041

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008703523

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 12449007

Country of ref document: US