WO2008086042A3 - Preventing infection by a measles or respiratory syncytial virus - Google Patents

Preventing infection by a measles or respiratory syncytial virus Download PDF

Info

Publication number
WO2008086042A3
WO2008086042A3 PCT/US2008/000449 US2008000449W WO2008086042A3 WO 2008086042 A3 WO2008086042 A3 WO 2008086042A3 US 2008000449 W US2008000449 W US 2008000449W WO 2008086042 A3 WO2008086042 A3 WO 2008086042A3
Authority
WO
WIPO (PCT)
Prior art keywords
measles
respiratory syncytial
syncytial virus
preventing infection
methods
Prior art date
Application number
PCT/US2008/000449
Other languages
French (fr)
Other versions
WO2008086042A2 (en
Inventor
Francis V Chisari
Philippe Gallay
Original Assignee
Francis V Chisari
Philippe Gallay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Francis V Chisari, Philippe Gallay filed Critical Francis V Chisari
Publication of WO2008086042A2 publication Critical patent/WO2008086042A2/en
Publication of WO2008086042A3 publication Critical patent/WO2008086042A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present application is directed to methods of inhibiting or preventing infection of a mammal by a measles virus and a respiratory syncytial virus, as well as methods of inactivating such viruses.
PCT/US2008/000449 2007-01-10 2008-01-10 Preventing infection by a measles or respiratory syncytial virus WO2008086042A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87972707P 2007-01-10 2007-01-10
US60/879,727 2007-01-10
US96781207P 2007-09-07 2007-09-07
US60/967,812 2007-09-07

Publications (2)

Publication Number Publication Date
WO2008086042A2 WO2008086042A2 (en) 2008-07-17
WO2008086042A3 true WO2008086042A3 (en) 2008-09-18

Family

ID=39609298

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/000449 WO2008086042A2 (en) 2007-01-10 2008-01-10 Preventing infection by a measles or respiratory syncytial virus

Country Status (1)

Country Link
WO (1) WO2008086042A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009014615A2 (en) * 2007-07-19 2009-01-29 The Board Of Trustees Of The Leland Stanford Junior University Amphipathic alpha-helical peptide compositions as antiviral agents
WO2009043518A2 (en) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
WO2011049914A2 (en) * 2009-10-22 2011-04-28 Board Of Regents Of The University Of Nebraska Anti-hiv peptides and methods of use thereof
WO2012040124A1 (en) 2010-09-22 2012-03-29 Alios Biopharma, Inc. Azido nucleosides and nucleotide analogs
AP2014007796A0 (en) 2011-12-22 2014-07-31 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
CA2989311A1 (en) 2015-07-02 2017-01-05 Dana-Farber Cancer Institute, Inc. Stabilized anti-microbial peptides
WO2017151617A1 (en) 2016-02-29 2017-09-08 Dana-Farber Cancer Institute, Inc. Stapled intracellular-targeting antimicrobial peptides to treat infection
US11325955B2 (en) 2017-07-19 2022-05-10 Dana-Farber Cancer Institute, Inc. Stabilized anti-microbial peptides for the treatment of antibiotic-resistant bacterial infections
EP3539562A1 (en) 2018-03-12 2019-09-18 Eberhard Karls Universität Tübingen Medizinische Fakultät Immunotherapeutic peptides

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BOBARDT ET AL.: "Hepatitis C virus NS5A anchor disrupts Human Immunodeficiency virus", vol. 105, no. 14, April 2008 (2008-04-01), pages 5525 - 5530 *
CHENG ET AL.: "A virocidal amphipathic alpha-helical peptide that inhibits Hepatitis C Virus in vitro", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 105, no. 8, February 2008 (2008-02-01), pages 3088 - 3093, XP002531867, DOI: doi:10.1073/PNAS.0712380105 *
ELAZAR ET AL.: "Amphipathic helix-dependent localization of NS5A mediates Hepatitis C Virus RNA replication", JOURNAL OF VIROLOGY, vol. 77, no. 10, May 2003 (2003-05-01), pages 6055 - 6061, XP002531868, DOI: doi:10.1128/JVI.77.10.6055 *
LAMBERT D.M. ET AL.: "Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 93, March 1996 (1996-03-01), pages 2186 - 2191, XP002161016 *
PARTIDOS ET AL.: "Structural requirements for synthetic immunogens to induce measles Virus specific CTL responses", MOLECULAR IMMUNOLOGY, vol. 33, no. 16, 1996, pages 1223 - 1229 *
SHEPERD ET AL.: "Modular alpha-helical mimetics with antiviral activity against Respiratory Syncytial Virus", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128, 2003, pages 13284 - 13289 *
WILD ET AL.: "Inhibition of Measles Virus infection and fusion with peptides corresponding to the leucine zipper region of the fusion protein", JOURNAL OF GENERAL VIROLOGY, vol. 78, 1997, pages 107 - 111, XP002614322 *

Also Published As

Publication number Publication date
WO2008086042A2 (en) 2008-07-17

Similar Documents

Publication Publication Date Title
WO2008086042A3 (en) Preventing infection by a measles or respiratory syncytial virus
WO2012083048A3 (en) Anti-viral compounds
WO2008113011A3 (en) Virus like particle purification
WO2009106019A3 (en) Chemical compounds having antiviral activity against dengue virus and other flaviviruses
WO2010030538A3 (en) Compounds for the treatment of hepatitis c
WO2008127364A3 (en) Antiviral compounds and use thereof
WO2011158039A8 (en) Ureido-pyrazole derivatives for use in the treatment of respiratory syncitial virus (rsv) infection
WO2008115281A3 (en) Compounds for treating viral infections
WO2011000566A3 (en) Compounds and pharmaceutical compositions for the treatment of negative-sense ssrna virus infections
WO2012083058A3 (en) Anti-viral compounds
WO2010062821A8 (en) Anti-viral compounds, compositions, and methods of use
AP2010005480A0 (en) Small molecule inhibitors for the treatment or prevention of denque virus infection.
HK1160724A1 (en) A method of inhibiting hepatitis c virus by combination of a 5,6-dihydro- 1h-pyridin-2-one and one or more additional antiviral compounds
WO2007084435A3 (en) Methods for treating hepatitis c
WO2009026179A3 (en) Antiinfective proanthocyanidin compounds and methods of use thereof
WO2010095041A3 (en) Compositions, methods, and kits for treating influenza viral infections
CA2818938A1 (en) Compounds for treating respiratory syncytial virus infections
WO2009029384A3 (en) Compounds for the treatment of hepatitis c
WO2007109105A3 (en) Flavivirus inhibition by sultams and related compounds
WO2007120595A3 (en) Amines for the treatment of hcv
WO2012162580A3 (en) Anti-viral compounds
WO2010052559A8 (en) Cycloundecadepsipeptide compounds and use of said compounds as a medicament
WO2012061248A8 (en) Novel specific hcv ns3 protease inhibitors
WO2010064822A3 (en) Effective control of viral plant disease with strains of pseudomonas oleovorans
WO2012048115A3 (en) Polypeptides and their use in treating and limiting respiratory syncytial virus infection

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08713114

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08713114

Country of ref document: EP

Kind code of ref document: A2