WO2008076557A3 - Détection d'allèles cyp2d6 - Google Patents

Détection d'allèles cyp2d6 Download PDF

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Publication number
WO2008076557A3
WO2008076557A3 PCT/US2007/084697 US2007084697W WO2008076557A3 WO 2008076557 A3 WO2008076557 A3 WO 2008076557A3 US 2007084697 W US2007084697 W US 2007084697W WO 2008076557 A3 WO2008076557 A3 WO 2008076557A3
Authority
WO
WIPO (PCT)
Prior art keywords
alleles
cyp2d6 alleles
detecting
detecting cyp2d6
cyp2d6
Prior art date
Application number
PCT/US2007/084697
Other languages
English (en)
Other versions
WO2008076557A2 (fr
Inventor
David A Mrazek
Iii John L Black
Dennis J O'kane
Original Assignee
Mayo Foundation
David A Mrazek
Iii John L Black
Dennis J O'kane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation, David A Mrazek, Iii John L Black, Dennis J O'kane filed Critical Mayo Foundation
Publication of WO2008076557A2 publication Critical patent/WO2008076557A2/fr
Publication of WO2008076557A3 publication Critical patent/WO2008076557A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne des procédés et des matériels intervenant dans la détection d'allèles CYP2D6 ou d'allèles recombinants CYP2D6 - CYP2D7 chez des mammifères (par exemple, chez des êtres humains).
PCT/US2007/084697 2006-11-14 2007-11-14 Détection d'allèles cyp2d6 WO2008076557A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85908106P 2006-11-14 2006-11-14
US60/859,081 2006-11-14
US90586207P 2007-03-08 2007-03-08
US60/905,862 2007-03-08

Publications (2)

Publication Number Publication Date
WO2008076557A2 WO2008076557A2 (fr) 2008-06-26
WO2008076557A3 true WO2008076557A3 (fr) 2008-08-21

Family

ID=39536942

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/084697 WO2008076557A2 (fr) 2006-11-14 2007-11-14 Détection d'allèles cyp2d6

Country Status (1)

Country Link
WO (1) WO2008076557A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113755578A (zh) * 2021-09-09 2021-12-07 上海普然生物科技有限公司 一种用于昂丹司琼和托烷司琼代谢标志物的检测试剂盒及其检测方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1281755A2 (fr) * 2001-07-31 2003-02-05 Pfizer Products Inc. Variants du gène humain cyp2d6
WO2004009760A2 (fr) * 2002-07-18 2004-01-29 Bioventures, Inc. Variations genetiques du cytochrome p 450

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1281755A2 (fr) * 2001-07-31 2003-02-05 Pfizer Products Inc. Variants du gène humain cyp2d6
WO2004009760A2 (fr) * 2002-07-18 2004-01-29 Bioventures, Inc. Variations genetiques du cytochrome p 450

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BODIN L. ET AL.: "Determination of Cytochrome P450 2D6 (CYP2D6) Gene Copy Number by Real-Time Quantitative PCR", J. BIOMED. BIOTECHNOL., vol. 2005, no. 3, 2005, pages 248 - 253 *
DATABASE GENBANK [online] 17 October 2006 (2006-10-17), accession no. NCBI Database accession no. (BX247885) *
DATABASE GENBANK [online] 19 October 2005 (2005-10-19), accession no. NCBI Database accession no. (DQ211353) *
JI L. ET AL.: "Genetic Polymorphisms of CYP2D6 in Chinese Mainland", CHIN. MED. J., vol. 115, no. 12, December 2002 (2002-12-01), pages 1780 - 1784 *
ROBERTS R.L. ET AL.: "Rapid Detection of Common Cytochrome P450 2D6 Alleles in Caucasians", CLIN. CHIM. ACTA, vol. 366, April 2006 (2006-04-01), pages 348 - 351, XP005320431 *

Also Published As

Publication number Publication date
WO2008076557A2 (fr) 2008-06-26

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