WO2008068217A3 - Pharmaceutical composition comprising a coated hmg-coa reductase inhibitor and an inhibitor of the renin-angiotensin system - Google Patents

Pharmaceutical composition comprising a coated hmg-coa reductase inhibitor and an inhibitor of the renin-angiotensin system Download PDF

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Publication number
WO2008068217A3
WO2008068217A3 PCT/EP2007/063138 EP2007063138W WO2008068217A3 WO 2008068217 A3 WO2008068217 A3 WO 2008068217A3 EP 2007063138 W EP2007063138 W EP 2007063138W WO 2008068217 A3 WO2008068217 A3 WO 2008068217A3
Authority
WO
WIPO (PCT)
Prior art keywords
inhibitor
pharmaceutical composition
renin
hmg
coated
Prior art date
Application number
PCT/EP2007/063138
Other languages
French (fr)
Other versions
WO2008068217A2 (en
Inventor
Andrea Staab
Amar Lulla
Geena Malhotra
Original Assignee
Boehringer Ingelheim Int
Boehringer Ingelheim Pharma
Andrea Staab
Amar Lulla
Geena Malhotra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Boehringer Ingelheim Pharma, Andrea Staab, Amar Lulla, Geena Malhotra filed Critical Boehringer Ingelheim Int
Publication of WO2008068217A2 publication Critical patent/WO2008068217A2/en
Publication of WO2008068217A3 publication Critical patent/WO2008068217A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Abstract

The invention describes a pharmaceutical composition comprising a cholesterol lowering agent in combination with an inhibitor of the renin angiotensin system (RAS) and a process of preparation thereof.
PCT/EP2007/063138 2006-12-04 2007-12-03 Pharmaceutical composition comprising a coated hmg-coa reductase inhibitor and an inhibitor of the renin-angiotensin system WO2008068217A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2578/DELNP/2006 2006-12-04
IN2578DE2006 2006-12-04

Publications (2)

Publication Number Publication Date
WO2008068217A2 WO2008068217A2 (en) 2008-06-12
WO2008068217A3 true WO2008068217A3 (en) 2008-08-14

Family

ID=39434009

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/063138 WO2008068217A2 (en) 2006-12-04 2007-12-03 Pharmaceutical composition comprising a coated hmg-coa reductase inhibitor and an inhibitor of the renin-angiotensin system

Country Status (1)

Country Link
WO (1) WO2008068217A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008235790B2 (en) 2007-03-28 2013-06-06 Takeda Pharmaceutical Company Limited Solid pharmaceutical composition comprising a benzimidazole-7-carboxylate derivative and a pH control agent
GEP20146062B (en) 2008-07-31 2014-03-25 Takeda Pharmaceuticals Co Solid pharmaceutical composition
CZ301299B6 (en) * 2008-11-24 2010-01-06 Zentiva, A.S. Solid pharmaceutical composition with atorvastatin and telmisartan active ingredients
KR101248804B1 (en) * 2010-05-14 2013-03-29 한미사이언스 주식회사 BILAYERED PHARMACEUTICAL COMPOSITION OF HMG-CoA REDUCTASE INHIBITOR AND IRBESARTAN
PL2814465T3 (en) * 2012-02-17 2020-01-31 Egis Gyógyszergyár Zrt. Pharmaceutical formulation having improved stability
IN2014MN01919A (en) * 2012-03-30 2015-07-10 Dae Woong Pharma
CN102908335B (en) * 2012-11-19 2015-04-08 山东罗欣药业集团股份有限公司 Rosuvastatain calcium composition and preparation method thereof
CN104224736A (en) * 2013-06-21 2014-12-24 哈药集团三精制药股份有限公司 Preparation method of simvastatin tablet
BR102013028883A2 (en) * 2013-11-08 2015-10-06 Hypermarcas S A oral dosage form for the prevention of vascular diseases, tablet as a dosage form and gelatin capsule as a dosage form
CN104306348B (en) * 2014-09-30 2017-05-31 地奥集团成都药业股份有限公司 A kind of Simvastatin Tablets and preparation method thereof
CN105273210B (en) * 2015-03-02 2021-07-06 北京工商大学 High-barrier composite film and preparation method thereof
CN105395551A (en) * 2015-11-19 2016-03-16 哈尔滨圣吉药业股份有限公司 Olmesartan medoxomil/rosuvastatin compound preparation and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020243A1 (en) * 2001-08-28 2003-03-13 Longwood Pharmaceutical Research, Inc. Combination dosage form containing a cholesterol -lowering agent , an inhibitor of the renin-angiotensin, and aspirin
WO2003092729A1 (en) * 2002-05-03 2003-11-13 Hexal Ag Stable pharmaceutical formulation for a combination of a statin and an ace inhibitor
US20060078615A1 (en) * 2004-10-12 2006-04-13 Boehringer Ingelheim International Gmbh Bilayer tablet of telmisartan and simvastatin
WO2007053406A1 (en) * 2005-10-28 2007-05-10 Novartis Ag Combinations of antihypertensive and cholesterol lowering agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020243A1 (en) * 2001-08-28 2003-03-13 Longwood Pharmaceutical Research, Inc. Combination dosage form containing a cholesterol -lowering agent , an inhibitor of the renin-angiotensin, and aspirin
WO2003092729A1 (en) * 2002-05-03 2003-11-13 Hexal Ag Stable pharmaceutical formulation for a combination of a statin and an ace inhibitor
US20060078615A1 (en) * 2004-10-12 2006-04-13 Boehringer Ingelheim International Gmbh Bilayer tablet of telmisartan and simvastatin
WO2007053406A1 (en) * 2005-10-28 2007-05-10 Novartis Ag Combinations of antihypertensive and cholesterol lowering agents

Also Published As

Publication number Publication date
WO2008068217A2 (en) 2008-06-12

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