WO2008065506A3 - Pharmaceutical compositions comprising nanoparticles comprising enteric polymers and casein - Google Patents

Pharmaceutical compositions comprising nanoparticles comprising enteric polymers and casein Download PDF

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Publication number
WO2008065506A3
WO2008065506A3 PCT/IB2007/003632 IB2007003632W WO2008065506A3 WO 2008065506 A3 WO2008065506 A3 WO 2008065506A3 IB 2007003632 W IB2007003632 W IB 2007003632W WO 2008065506 A3 WO2008065506 A3 WO 2008065506A3
Authority
WO
WIPO (PCT)
Prior art keywords
nanoparticles
casein
pharmaceutical compositions
enteric polymers
phenyl
Prior art date
Application number
PCT/IB2007/003632
Other languages
French (fr)
Other versions
WO2008065506A2 (en
Inventor
Ronald Arthur Beyerinck
Corey Jay Bloom
Marshall David Crew
Dwayne Thomas Friesen
Michael Mark Morgen
Daniel Tod Smithey
Original Assignee
Pfizer Prod Inc
Ronald Arthur Beyerinck
Corey Jay Bloom
Marshall David Crew
Dwayne Thomas Friesen
Michael Mark Morgen
Daniel Tod Smithey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc, Ronald Arthur Beyerinck, Corey Jay Bloom, Marshall David Crew, Dwayne Thomas Friesen, Michael Mark Morgen, Daniel Tod Smithey filed Critical Pfizer Prod Inc
Publication of WO2008065506A2 publication Critical patent/WO2008065506A2/en
Publication of WO2008065506A3 publication Critical patent/WO2008065506A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes

Abstract

A pharmaceutical composition comprises nanoparticles comprising the poorly water soluble lipophilic compound (2R)-3-[[3-(4-chloro-3-ethylphenoxy)phenyl][[3-(1,1,2,2- tetrafluoroethoxy)phenyl]methyl]amino]-1,1,1-trifluoro-2-propanol, and an enteric polymer.
PCT/IB2007/003632 2006-11-29 2007-11-16 Pharmaceutical compositions comprising nanoparticles comprising enteric polymers and casein WO2008065506A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86766206P 2006-11-29 2006-11-29
US60/867,662 2006-11-29

Publications (2)

Publication Number Publication Date
WO2008065506A2 WO2008065506A2 (en) 2008-06-05
WO2008065506A3 true WO2008065506A3 (en) 2009-06-25

Family

ID=39295581

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/003632 WO2008065506A2 (en) 2006-11-29 2007-11-16 Pharmaceutical compositions comprising nanoparticles comprising enteric polymers and casein

Country Status (1)

Country Link
WO (1) WO2008065506A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2583672A1 (en) * 2011-10-17 2013-04-24 PharmaSol GmbH Nanocrystals and amorphous nanoparticles and method for production of the same by a low energy process
US10500282B2 (en) 2012-12-19 2019-12-10 Kashiv Biosciences, Llc Supersaturated stabilized nanoparticles for poorly soluble drugs
EP3968964A1 (en) * 2019-05-16 2022-03-23 Leon-Nanodrugs GmbH Method for producing nanoparticles

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000226A2 (en) * 2001-06-22 2003-01-03 Pfizer Products Inc. Pharmaceutical compositions containing polymer and drug assemblies
WO2003063868A1 (en) * 2002-02-01 2003-08-07 Pfizer Products Inc. Controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor
WO2004056359A1 (en) * 2002-12-20 2004-07-08 Pfizer Products Inc. Dosage forms comprising a cetp inhibitor and an hmg-coa reductase inhibitor
WO2006129167A1 (en) * 2005-05-31 2006-12-07 Pfizer Products Inc. PHARMACEUTICAL COMPOSITIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG-CoA REDUCTASE INHIBITORS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000226A2 (en) * 2001-06-22 2003-01-03 Pfizer Products Inc. Pharmaceutical compositions containing polymer and drug assemblies
WO2003063868A1 (en) * 2002-02-01 2003-08-07 Pfizer Products Inc. Controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor
WO2004056359A1 (en) * 2002-12-20 2004-07-08 Pfizer Products Inc. Dosage forms comprising a cetp inhibitor and an hmg-coa reductase inhibitor
WO2006129167A1 (en) * 2005-05-31 2006-12-07 Pfizer Products Inc. PHARMACEUTICAL COMPOSITIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG-CoA REDUCTASE INHIBITORS

Also Published As

Publication number Publication date
WO2008065506A2 (en) 2008-06-05

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