WO2008063943A3 - Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain - Google Patents

Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain Download PDF

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Publication number
WO2008063943A3
WO2008063943A3 PCT/US2007/084387 US2007084387W WO2008063943A3 WO 2008063943 A3 WO2008063943 A3 WO 2008063943A3 US 2007084387 W US2007084387 W US 2007084387W WO 2008063943 A3 WO2008063943 A3 WO 2008063943A3
Authority
WO
WIPO (PCT)
Prior art keywords
adhesive compositions
pain
controlling inflammation
increasing efficacy
injury
Prior art date
Application number
PCT/US2007/084387
Other languages
French (fr)
Other versions
WO2008063943A4 (en
WO2008063943A2 (en
Inventor
Kathy L Chamness
Original Assignee
Warsaw Orthopedic Inc
Kathy L Chamness
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warsaw Orthopedic Inc, Kathy L Chamness filed Critical Warsaw Orthopedic Inc
Priority to EP07864257.6A priority Critical patent/EP2104505B1/en
Priority to ES07864257.6T priority patent/ES2493567T3/en
Publication of WO2008063943A2 publication Critical patent/WO2008063943A2/en
Publication of WO2008063943A3 publication Critical patent/WO2008063943A3/en
Publication of WO2008063943A4 publication Critical patent/WO2008063943A4/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method and kits thereof for increasing the efficiency of anti-adhesive compositions by parenterally administering a composition comprising an effective amount of at least one pharmaceutically-acceptable anti-adhesive non-ionic polymer and at least one magnesium salts to a site on injury, controlling inflammation at the site of injury, and reducing pain.
PCT/US2007/084387 2006-11-13 2007-11-12 Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain WO2008063943A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07864257.6A EP2104505B1 (en) 2006-11-14 2007-11-12 Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain
ES07864257.6T ES2493567T3 (en) 2006-11-13 2007-11-12 Procedure and use to increase the effectiveness of non-stick compositions to control inflammation and pain

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/598,397 2006-11-13
US11/598,397 US9675696B2 (en) 2006-11-14 2006-11-14 Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain

Publications (3)

Publication Number Publication Date
WO2008063943A2 WO2008063943A2 (en) 2008-05-29
WO2008063943A3 true WO2008063943A3 (en) 2009-05-07
WO2008063943A4 WO2008063943A4 (en) 2009-07-02

Family

ID=39267877

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/084387 WO2008063943A2 (en) 2006-11-13 2007-11-12 Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain

Country Status (4)

Country Link
US (1) US9675696B2 (en)
EP (2) EP2465513A3 (en)
ES (1) ES2493567T3 (en)
WO (1) WO2008063943A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US8945623B2 (en) * 2006-05-03 2015-02-03 Warsaw Orthopedic, Inc. Compositions comprising biomembrane sealing agent for treatment of neuronal injury, and methods of use
WO2010111212A1 (en) * 2009-03-26 2010-09-30 Warsaw Orthopedic, Inc. Methods of identifying potential components for targeted drug delivery compositions
DK2968159T3 (en) * 2013-03-15 2019-08-12 Midway Pharmaceuticals Inc TREATMENT OF OSTEOPOROSIS WITH HMW PEG
EP3746393A4 (en) 2018-02-02 2021-11-03 Galen Therapeutics Llc Apparatus and method for protecting neurons and reducing inflammation and scarring
EP3863686A1 (en) * 2018-10-12 2021-08-18 Advanced Accelerator Applications International S.A. Pharmaceutical composition comprising a radiolabeled gprp antagonist and a surfactant

Citations (3)

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Publication number Priority date Publication date Assignee Title
US6037331A (en) * 1996-07-19 2000-03-14 Poly-Med, Inc. Compositions for prevention of inflammation and adhesion formation uses thereof
US20050074495A1 (en) * 1997-06-17 2005-04-07 Fziomed, Inc. Compositions of polyacids and methods for their use in reducing adhesions
US20070258938A1 (en) * 2006-05-03 2007-11-08 Josee Roy Compositions comprising biomembrane sealing agent for treatment of pain or inflammation, and methods of use

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US3026248A (en) * 1959-09-11 1962-03-20 Pfizer & Co C Thioglycerol and formaldehyde sulfoxylate stabilized tetracycline antibiotics in polyhydric alcohol solvents
GB1250304A (en) 1969-03-13 1971-10-20
DE2001604C2 (en) 1970-01-15 1983-04-14 Pfizer Gmbh, 7500 Karlsruhe Use of polyethylene glycol for the production of oxytetracycline solutions for parenteral, peroral and local application
DK138974B (en) * 1974-02-19 1978-11-27 Ciba Geigy Ag Process for the preparation of aqueous oxytetracycline solutions for parenteral, oral and topical use.
US4451447A (en) * 1980-03-31 1984-05-29 Bristol-Myers Company Pharmaceutical formulations
US5605687A (en) * 1992-05-15 1997-02-25 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for repair of electrical injury
US5686488A (en) * 1995-08-25 1997-11-11 Alcon Laboratories, Inc. Polyethoxylated castor oil products as anti-inflammatory agents
US6869938B1 (en) * 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
SE9702698D0 (en) 1997-07-14 1997-07-14 Stig Bengmark Compositions for lubricating and separating tissues and biological membranes
ES2210808T3 (en) 1997-08-27 2004-07-01 California Institute Of Technology COMPOSITIONS AND THEIR USE TO PREVENT THE FORMATION OF ADHERENCES IN A BIOLOGICAL FABRIC.
US7582680B1 (en) * 1998-11-12 2009-09-01 Purdue Research Foundation Methods and compositions for treating mammalian spinal cord injuries
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
ES2223583T3 (en) * 1999-07-28 2005-03-01 United States Surgical Corporation ANTIADHERENT BARRIER OF HIALURONIC ACID.
CA2382864A1 (en) 1999-10-15 2001-04-26 The Dow Chemical Company Dialysis solution including polyglycol osmotic agent
US6566345B2 (en) * 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
WO2001087234A2 (en) * 2000-05-12 2001-11-22 Supratek Pharma Inc. Treatment of autoimmune, proliferative and inflammatory diseases with compositions of non-ionic copolymers
IL156618A0 (en) * 2000-12-28 2004-01-04 Altus Biologics Inc Crystals of whole antibodies and fragments thereof, methods for the preparation thereof and diagnostic kits utilizing the same
NZ543953A (en) * 2001-04-24 2007-04-27 Univ Chicago Method and compositions for treating mammalian nerve tissue injuries
EP1458408B1 (en) * 2001-12-21 2009-04-15 Novo Nordisk Health Care AG Liquid composition of factor vii polypeptides
US20040258757A1 (en) * 2002-07-16 2004-12-23 Elan Pharma International, Ltd. Liquid dosage compositions of stable nanoparticulate active agents
JP2006517807A (en) * 2002-12-30 2006-08-03 パーデュー・リサーチ・ファウンデーション Treatment of central nervous system damage
EP1819297B1 (en) * 2004-09-28 2015-01-14 Atrium Medical Corporation Uv cured gel and method of making
US8414907B2 (en) * 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US8153112B2 (en) * 2007-08-03 2012-04-10 Warsaw Orthopedic, Inc. Compositions and methods for treating cavity conditions
US8852566B2 (en) * 2009-03-26 2014-10-07 Warsaw Orthopedic, Inc. Compositions and methods for preferential distribution of active agents to injury sites
US9244060B2 (en) * 2009-03-26 2016-01-26 Warsaw Orthopedic, Inc. Site localization and methods for monitoring treatment of disturbed blood vessels

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037331A (en) * 1996-07-19 2000-03-14 Poly-Med, Inc. Compositions for prevention of inflammation and adhesion formation uses thereof
US20050074495A1 (en) * 1997-06-17 2005-04-07 Fziomed, Inc. Compositions of polyacids and methods for their use in reducing adhesions
US20070258938A1 (en) * 2006-05-03 2007-11-08 Josee Roy Compositions comprising biomembrane sealing agent for treatment of pain or inflammation, and methods of use

Also Published As

Publication number Publication date
WO2008063943A4 (en) 2009-07-02
ES2493567T3 (en) 2014-09-12
EP2465513A2 (en) 2012-06-20
WO2008063943A2 (en) 2008-05-29
EP2104505A2 (en) 2009-09-30
EP2104505B1 (en) 2014-05-21
US20080112921A1 (en) 2008-05-15
US9675696B2 (en) 2017-06-13
EP2465513A3 (en) 2013-01-02

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