WO2008063643A3 - Method and apparatus for analyte processing - Google Patents

Method and apparatus for analyte processing Download PDF

Info

Publication number
WO2008063643A3
WO2008063643A3 PCT/US2007/024265 US2007024265W WO2008063643A3 WO 2008063643 A3 WO2008063643 A3 WO 2008063643A3 US 2007024265 W US2007024265 W US 2007024265W WO 2008063643 A3 WO2008063643 A3 WO 2008063643A3
Authority
WO
WIPO (PCT)
Prior art keywords
channels
processing
samples
fluid reservoir
dowel
Prior art date
Application number
PCT/US2007/024265
Other languages
French (fr)
Other versions
WO2008063643A2 (en
Inventor
David Brancazio
Brett Masters
Eric France
Matthew Kavalauskas
Peter Wight Falb
Original Assignee
Bioscale Inc
David Brancazio
Brett Masters
Eric France
Matthew Kavalauskas
Peter Wight Falb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/603,285 external-priority patent/US20080118402A1/en
Priority claimed from US11/603,347 external-priority patent/US8202491B2/en
Application filed by Bioscale Inc, David Brancazio, Brett Masters, Eric France, Matthew Kavalauskas, Peter Wight Falb filed Critical Bioscale Inc
Priority to EP07853146A priority Critical patent/EP2095103A2/en
Publication of WO2008063643A2 publication Critical patent/WO2008063643A2/en
Publication of WO2008063643A3 publication Critical patent/WO2008063643A3/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1253—Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
    • F04B43/1292—Pumps specially adapted for several tubular flexible members
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/022—Fluid sensors based on microsensors, e.g. quartz crystal-microbalance [QCM], surface acoustic wave [SAW] devices, tuning forks, cantilevers, flexural plate wave [FPW] devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/036—Analysing fluids by measuring frequency or resonance of acoustic waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/44—Processing the detected response signal, e.g. electronic circuits specially adapted therefor
    • G01N29/4409—Processing the detected response signal, e.g. electronic circuits specially adapted therefor by comparison
    • G01N29/4436—Processing the detected response signal, e.g. electronic circuits specially adapted therefor by comparison with a reference signal
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/025—Change of phase or condition
    • G01N2291/0256—Adsorption, desorption, surface mass change, e.g. on biosensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/028—Material parameters
    • G01N2291/02881—Temperature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/04—Wave modes and trajectories
    • G01N2291/042—Wave modes
    • G01N2291/0427—Flexural waves, plate waves, e.g. Lamb waves, tuning fork, cantilever
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis

Abstract

The invention relates to a system for processing an analyte. The system includes a fluid reservoir, a plurality of sample reservoirs, a plurality of channels, a pump that synchronously draws from the fluid reservoir and the plurality of sample reservoirs to provide a plurality of samples through the plurality of channels and a processing device, for example, a flexural plate wave device, for processing the plurality of samples in the plurality of channels. A valve including a pin disposed beneath a dowel and a pusher pushes the pin toward a fastened dowel, which pinches a portion of the channel disposed there between. A socket provides electrical contact to the processing device.
PCT/US2007/024265 2006-11-21 2007-11-20 Method and apparatus for analyte processing WO2008063643A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07853146A EP2095103A2 (en) 2006-11-21 2007-11-20 Method and apparatus for analyte processing

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/603,285 US20080118402A1 (en) 2006-11-21 2006-11-21 Method and apparatus for analyte processing
US11/603,347 2006-11-21
US11/603,347 US8202491B2 (en) 2006-11-21 2006-11-21 Apparatus for analyte processing
US11/603,285 2006-11-21

Publications (2)

Publication Number Publication Date
WO2008063643A2 WO2008063643A2 (en) 2008-05-29
WO2008063643A3 true WO2008063643A3 (en) 2008-09-25

Family

ID=39204033

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/024265 WO2008063643A2 (en) 2006-11-21 2007-11-20 Method and apparatus for analyte processing

Country Status (2)

Country Link
EP (1) EP2095103A2 (en)
WO (1) WO2008063643A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101468593B1 (en) 2008-08-14 2014-12-04 삼성전자주식회사 Wave sensor apparatus comprising gas removing unit and method of detecting target material in liquid sample
US20160010635A1 (en) * 2014-07-09 2016-01-14 Perkinelmer Health Sciences, Inc. Peristaltic pump and related methods
CN110075935B (en) * 2019-04-23 2020-06-19 清华大学 Multi-index detection microfluidic card box and application method
CN110057624B (en) * 2019-04-28 2024-04-05 深圳市大肯科技有限公司 Air pump

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030154031A1 (en) * 2002-02-14 2003-08-14 General Electric Company Method and apparatus for the rapid evaluation of a plurality of materials or samples
WO2005111426A1 (en) * 2004-05-18 2005-11-24 Matsushita Electric Industrial Co., Ltd. Tube cassette unit and liquid conveyance device using the same
US7118922B1 (en) * 2003-08-15 2006-10-10 University Of South Florida System and method for immunosensor regeneration
WO2006119308A2 (en) * 2005-05-02 2006-11-09 Bioscale, Inc. Method and apparatus for detecting analytes using an acoustic device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020022261A1 (en) * 1995-06-29 2002-02-21 Anderson Rolfe C. Miniaturized genetic analysis systems and methods
AU702403B2 (en) * 1995-12-05 1999-02-18 Gamera Bioscience Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
WO2001071336A1 (en) * 2000-03-20 2001-09-27 The Charles Stark Draper Laboratory, Inc. Flexural plate wave sensor and array

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030154031A1 (en) * 2002-02-14 2003-08-14 General Electric Company Method and apparatus for the rapid evaluation of a plurality of materials or samples
US7118922B1 (en) * 2003-08-15 2006-10-10 University Of South Florida System and method for immunosensor regeneration
WO2005111426A1 (en) * 2004-05-18 2005-11-24 Matsushita Electric Industrial Co., Ltd. Tube cassette unit and liquid conveyance device using the same
EP1752663A1 (en) * 2004-05-18 2007-02-14 Matsushita Electric Industries Co., Ltd. Tube cassette unit and liquid conveyance device using the same
WO2006119308A2 (en) * 2005-05-02 2006-11-09 Bioscale, Inc. Method and apparatus for detecting analytes using an acoustic device

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GRATE AND FRYE: "Acoustic Wave Sensors", SENSORS UPDATE, XX, XX, 1996, pages 37 - 83, XP002205093 *
See also references of EP2095103A2 *

Also Published As

Publication number Publication date
EP2095103A2 (en) 2009-09-02
WO2008063643A2 (en) 2008-05-29

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