WO2008062274A3 - Pharmaceutical formulations of nsaids for parentral use - Google Patents

Pharmaceutical formulations of nsaids for parentral use Download PDF

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Publication number
WO2008062274A3
WO2008062274A3 PCT/IB2007/003515 IB2007003515W WO2008062274A3 WO 2008062274 A3 WO2008062274 A3 WO 2008062274A3 IB 2007003515 W IB2007003515 W IB 2007003515W WO 2008062274 A3 WO2008062274 A3 WO 2008062274A3
Authority
WO
WIPO (PCT)
Prior art keywords
nsaids
parentral
pharmaceutical formulations
pharmaceutical composition
stable pharmaceutical
Prior art date
Application number
PCT/IB2007/003515
Other languages
French (fr)
Other versions
WO2008062274A2 (en
Inventor
Indravadan Ambalal Modi
Ashok Omray
Sachin K Salampure
Bakulesh Mafatlal Khamar
Original Assignee
Cadila Pharmaceuticals Ltd
Indravadan Ambalal Modi
Ashok Omray
Sachin K Salampure
Bakulesh Mafatlal Khamar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Pharmaceuticals Ltd, Indravadan Ambalal Modi, Ashok Omray, Sachin K Salampure, Bakulesh Mafatlal Khamar filed Critical Cadila Pharmaceuticals Ltd
Publication of WO2008062274A2 publication Critical patent/WO2008062274A2/en
Publication of WO2008062274A3 publication Critical patent/WO2008062274A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates

Abstract

The novel stable pharmaceutical composition comprising non-steroidal anti inflammatory drug (NSAIDs), as injectables, which provides a clear and stable pharmaceutical composition without incorporation of any additives.
PCT/IB2007/003515 2006-11-20 2007-11-16 Pharmaceutical formulations of nsaids for parentral use WO2008062274A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1904MU2006 2006-11-20
IN1904/MUM/2006 2006-11-20

Publications (2)

Publication Number Publication Date
WO2008062274A2 WO2008062274A2 (en) 2008-05-29
WO2008062274A3 true WO2008062274A3 (en) 2009-04-23

Family

ID=39430108

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/003515 WO2008062274A2 (en) 2006-11-20 2007-11-16 Pharmaceutical formulations of nsaids for parentral use

Country Status (1)

Country Link
WO (1) WO2008062274A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019214715A1 (en) 2018-05-11 2019-11-14 南京清普生物科技有限公司 Meloxicam composition, preparation and preparation method and use thereof
WO2021224815A1 (en) * 2020-05-06 2021-11-11 Cadila Healthcare Limited Stable aqueous parenteral solutions of nonsteroidal anti-inflammatory drug (nsaid)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374826A (en) * 1980-07-21 1983-02-22 Pfizer Inc. Sulfonamide compositions
US20020035107A1 (en) * 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
US20050187212A1 (en) * 2002-09-17 2005-08-25 Nippon Boehringer Ingelheim Co., Ltd. Pharmaceutical composition for topical delivery of meloxicam

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374826A (en) * 1980-07-21 1983-02-22 Pfizer Inc. Sulfonamide compositions
US20020035107A1 (en) * 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
US20050187212A1 (en) * 2002-09-17 2005-08-25 Nippon Boehringer Ingelheim Co., Ltd. Pharmaceutical composition for topical delivery of meloxicam

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ROWE ET AL.: "Handbook of Pharmaceutical Excipients", 2006, pages: 633 - 634 *

Also Published As

Publication number Publication date
WO2008062274A2 (en) 2008-05-29

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