WO2008058455A1 - Dispositif d'administration d'un médicament pour affections pulmonaires - Google Patents

Dispositif d'administration d'un médicament pour affections pulmonaires Download PDF

Info

Publication number
WO2008058455A1
WO2008058455A1 PCT/CN2007/003181 CN2007003181W WO2008058455A1 WO 2008058455 A1 WO2008058455 A1 WO 2008058455A1 CN 2007003181 W CN2007003181 W CN 2007003181W WO 2008058455 A1 WO2008058455 A1 WO 2008058455A1
Authority
WO
WIPO (PCT)
Prior art keywords
atomizer
liquid supply
delivery device
drug delivery
intrapulmonary drug
Prior art date
Application number
PCT/CN2007/003181
Other languages
English (en)
Chinese (zh)
Inventor
Wenbo Li
Original Assignee
Tafelberg International Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tafelberg International Limited filed Critical Tafelberg International Limited
Publication of WO2008058455A1 publication Critical patent/WO2008058455A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0085—Inhalators using ultrasonics

Definitions

  • Intrapulmonary drug delivery device Intrapulmonary drug delivery device
  • the present invention relates to a medical device for use in an alveolar absorbing drug, and more particularly to an intrapulmonary drug delivery device for atomizing a drug dissolved in a liquid into microparticles deep into the alveoli.
  • the existing intrapulmonary drug delivery device for medical purposes is mostly divided into a high-pressure gas tank spraying device and an ultrasonic atomizing device.
  • a high-pressure gas tank spraying device and an ultrasonic atomizing device.
  • the alveoli absorb drugs.
  • the existing intrapulmonary drug delivery device represents a stage of development of a technique, there are also defects such as inconvenience in carrying, excessive atomization of particles, and uncontrollable inhalation of the atomizing agent.
  • the present invention provides an intrapulmonary drug delivery device which has small atomized particles of a liquid medicine, is atomized, and can control the amount of administration, and has a small volume and is easy to carry.
  • the main technical solution for the present invention is: an intrapulmonary drug delivery device comprising a housing, a nozzle communicating with the housing, a battery, a liquid supply bottle and an atomizer housed in the housing,
  • the liquid supply bottle cooperates with the atomizer to transfer the medical liquid to the atomizer
  • the battery is electrically connected to the atomizer and controlled by an action switch
  • the housing is provided with an air inlet.
  • the liquid supply bottle is located between the suction nozzle and the atomizer, one end is in communication with the suction nozzle, and the other end is in contact with the atomizer; the outer surface of the liquid supply bottle An air passage is opened, the air passage is in communication with the nozzle, and the air inlet corresponds to the position of the atomizer;
  • the atomizer is a jet heating atomizer, comprising a liquid supply structure and a heating body, wherein the liquid supply structure is a porous body structure or a fiber structure, and one end has a jet hole and the other end forms a protrusion;
  • the liquid supply bottle is in contact with the protrusion, so that the chemical liquid penetrates into the liquid supply structure, and the heating body is accommodated in the liquid supply structure and electrically connected to the battery;
  • the atomizer is an infiltration heating atomizer, comprising a liquid supply structure and a heating body, wherein the liquid supply structure is a porous structure or a fiber structure, one end of which forms a protrusion, and the other end of which the heating body is mounted, The heating body is electrically connected to the battery, and the liquid supply bottle is in contact with the protrusion to infiltrate the liquid supply structure into the liquid supply structure;
  • the heating body is a metal heating wire, and may also be a conductive ceramic or PTC ceramic;
  • a gas-liquid separator is further disposed between the air inlet and the atomizer;
  • a quantitative device is disposed in the casing, and the casing is provided with a cleaning pipeline;
  • the liquid supply bottle is a porous body structure or a fiber structure
  • the action switch can be a manual switch, or can be made of a pneumatic/airflow sensor, a Hall device, a semiconductor force sensitive chip, a semiconductor matrix thermal bridge chip or a capacitive and inductive sensor;
  • the quantitative device includes a bridge circuit and a sampling circuit a pulse generator or an analog circuit, a general-purpose circuit of the microprocessor;
  • the quantitative device applies a rectangular pulse power supply to the atomizer, and detects a resistance value of the heating body due to the temperature coefficient at intervals of the rectangular pulse signal, thereby Quantitative atomization is realized by adjusting the power supply pulse width by the microprocessor;
  • the dosing device directly detects the voltage drop of the heating body due to the temperature coefficient, and adjusts the supply current through the microprocessor to achieve quantitative atomization.
  • the atomizing crucible of the present invention uses a jet heating atomizer to perform atomization in the jet hole 103 by the suction airflow, and sprays it on the heating body 102 for secondary atomization.
  • the two atomizations make the atomization more uniform, the atomized particles are small, and the average diameter can reach about 1 micron, which is beneficial to the lungs to fully absorb the liquid, and is the best technical parameter for intrapulmonary absorption.
  • the present invention is provided with a metering device for controlling the amount of administration.
  • the invention provides a battery, an 'atomizer, a liquid supply bottle and the like in the casing, so that the volume is reduced and portable, and can be applied to outdoor medical treatment.
  • Figure 1 is a schematic structural view of the present invention
  • Figure 2 is a right side view of Figure 1;
  • FIG. 3 is a schematic structural view of a jet heating atomizer according to a first embodiment of the present invention
  • FIG. 4 is a right side view of FIG.
  • Figure 5 is a schematic view showing the structure of the infiltration heat atomizer in the second embodiment of the present invention.
  • Figure 6 is a right side view of Figure 5.
  • FIG. 1 to FIG. 6 show an intrapulmonary drug delivery device according to the present invention, comprising a housing 10, a nozzle 2 communicating with the housing 10, and a battery 1 housed in the housing 10.
  • a liquid supply bottle 3 and an atomizer 5 the liquid supply bottle 3 cooperates with the atomizer 5 to transfer the medical liquid to the atomizer 5, and the battery 1 is electrically connected to the atomizer 5 and is
  • the action switch 7 controls that the housing 10 has an air inlet.
  • the liquid supply bottle 3 is located between the suction nozzle 2 and the atomizer 5, one end is in communication with the suction nozzle 2, and the other end is in contact with the atomizer 5.
  • the liquid supply bottle 3 is a porous body structure or a fiber structure and can be replaced.
  • the outer surface of the liquid supply bottle 3 is provided with an air passage 12, the air passage 12 is in communication with the suction nozzle 2, the air inlet corresponds to the position of the atomizer 5, and an air filter 9 is provided at the air inlet. The inhaled outside air is filtered through it and enters the casing 10.
  • a gas-liquid barrier film 8 is provided between the air inlet and the atomizer 5 for separating the liquid medicine and the air so that the entire device does not leak. At the same time, a certain amount of the device 6 is added to the casing 10 in order to control the dose to be administered.
  • a cleaning duct 4 can also be opened in the casing 10.
  • An action switch 7 is also mounted on the housing 10, which is connected in series with the battery 1 and the atomizer 5 via the dosing device 6.
  • the action switch 7 can be a manual switch or can be made of a pneumatic/airflow sensor, a Hall device, a semiconductor force sensitive chip, a semiconductor matrix thermobridge chip or a capacitive and inductive sensor.
  • the atomizer 5 is a jet heating atomizer, and includes a liquid supply structure 101 and a heating body 102, and the liquid supply structure 101
  • the porous body structure or the fiber structure has a jet hole 103 at one end and a protrusion 104 at the other end.
  • the heating body 102 is housed in the liquid supply structure 101 and electrically connected to the battery 1, and is controlled by the action switch 7.
  • the liquid supply bottle 3 is in contact with the projection 104 to allow the chemical solution to permeate into the liquid supply structure 101.
  • the heating body 102 is a metal heating wire, and may also be a conductive ceramic or a PTC ceramic.
  • the jet heating atomizer is atomized in the jet hole 103 by the suction airflow, and is sprayed on the heating body 102 for secondary atomization. Due to the two atomizations, the atomization is uniform and the atomized particles are small, and the average diameter can reach about 1 micrometer, which is beneficial to the lungs to fully absorb the liquid, and is the best technical parameter for absorption in the lung. ''.;
  • the atomizer 5 is an infiltration heating atomizer, and includes a liquid supply structure 201 and a heating body 202.
  • the liquid supply structure 201 is a porous body structure or a fiber structure, and one end thereof is formed with a protrusion 204, and the other end is provided with a heating body. 202.
  • the heating body 202 is electrically connected to the battery 1 and is controlled by an action switch 7.
  • the liquid supply bottle 3 is in contact with the projection 204 to allow the chemical solution to permeate into the liquid supply structure 201.
  • the heating body 202 is a metal heating wire, also a conductive ceramic or a PTC ceramic.
  • the infiltration heating atomizer directly heats the liquid supply structure 201 by the heating body 202 to atomize the liquid.
  • the projections 104, 204 at one end are connected to the liquid supply bottle 3, and the liquid medicine in the liquid supply bottle 3 gradually passes through the liquid supply structural bodies 101, 201.
  • the liquid supply structures 101, 201 are formed by foaming ceramics, microporous ceramics, porous metal, stainless steel fiber felt or chemical fiber forming openings.
  • the heating bodies 102, 202 are made of a metal electrothermal material surrounded by a microporous ceramic skeleton, or a porous body with a sintered electrode which is directly made of a conductive ceramic or a PTC ceramic material. The surface of the heating body is sintered into a high temperature glaze to fix the zeolite particles, and the zeolite particles are made of natural zeolite, artificial inorganic microporous ceramic or alumina particles.
  • the above two embodiments provided by the invention operate on the principle that: after the drug is dissolved in propylene glycol, the drug solution is filled into the replaceable liquid supply bottle 3.
  • the liquid supply bottle 3 is placed in the casing 10, brought into contact with the atomizer 5, and supplied with liquid to the atomizer.
  • the action switch 7 is pressed, the circuit is turned on, the battery 1 supplies power to the atomizer 5, and the heating bodies 102, 202 start heating.
  • the work indicator lamp 11 emits light, and the outside air is filtered through the air filter sheet 9 and then enters the casing 10, and after being mixed with the liquid medicine through the gas-liquid separator 8, is atomized by the atomizer 5.
  • the aerosol is inhaled into the lungs by the user through the airway 12 and through the mouthpiece 2.
  • the dosing device 6 sets the dose for each administration in advance, and performs atomization quantification on the atomization process.
  • the dosing device 6 includes a bridge circuit, a sampling circuit, a pulse generator or an analog circuit, and a microprocessor general circuit.
  • the working principle of the dosing device 6 is to supply a rectangular pulse to the atomizer, and to detect the resistance value of the heating body 102 due to the temperature coefficient during the interval of the rectangular pulse signal, thereby adjusting the power supply pulse width by the microprocessor. Achieve quantitative atomization.
  • the working principle of the measuring device 6 is: directly detecting the voltage drop of the heating body 102 due to the temperature coefficient, and adjusting the supply current through the microprocessor to achieve quantitative fogging.
  • the user can clean the device through the cleaning pipe 4 with water or ethanol solution when needed.
  • the invention can be used for administration of bronchioles and alveoli.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nozzles (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Un dispositif d'administration d'un médicament destiné aux affections pulmonaires comprend un boîtier (10), une embouchure (2) communiquant avec le boîtier (10), et une batterie (1), une bouteille d'alimentation en liquide (3) et un atomiseur (5) qui sont contenus dans ledit boîtier (10). La bouteille d'alimentation en liquide (3) est associée avec l'atomiseur (5) de manière à distribuer le liquide médicamenteux à l'atomiseur (5). La batterie (1) est connectée électriquement avec l'atomiseur (5) et est commandée par un interrupteur d'actionnement (7). Le boîtier (10) présente un orifice d'aération.
PCT/CN2007/003181 2006-11-11 2007-11-09 Dispositif d'administration d'un médicament pour affections pulmonaires WO2008058455A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200610148464.2 2006-11-11
CNB2006101484642A CN100536951C (zh) 2006-11-11 2006-11-11 肺内给药装置

Publications (1)

Publication Number Publication Date
WO2008058455A1 true WO2008058455A1 (fr) 2008-05-22

Family

ID=39401316

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2007/003181 WO2008058455A1 (fr) 2006-11-11 2007-11-09 Dispositif d'administration d'un médicament pour affections pulmonaires

Country Status (2)

Country Link
CN (1) CN100536951C (fr)
WO (1) WO2008058455A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109985297A (zh) * 2019-05-17 2019-07-09 深圳市柏明胜医疗器械有限公司 一种药瓶
CN114832191A (zh) * 2022-04-12 2022-08-02 卜鹿生物技术(成都)有限公司 二次雾化装置及药物雾化系统

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100381083C (zh) 2003-04-29 2008-04-16 韩力 一种非可燃性电子喷雾香烟
CN2719043Y (zh) 2004-04-14 2005-08-24 韩力 雾化电子烟
CN201067079Y (zh) 2006-05-16 2008-06-04 韩力 仿真气溶胶吸入器
US7726320B2 (en) 2006-10-18 2010-06-01 R. J. Reynolds Tobacco Company Tobacco-containing smoking article
CN201379072Y (zh) 2009-02-11 2010-01-13 韩力 一种改进的雾化电子烟
CN201445686U (zh) * 2009-06-19 2010-05-05 李文博 高频感应雾化装置
US9095175B2 (en) 2010-05-15 2015-08-04 R. J. Reynolds Tobacco Company Data logging personal vaporizing inhaler
US10136672B2 (en) 2010-05-15 2018-11-27 Rai Strategic Holdings, Inc. Solderless directly written heating elements
US10159278B2 (en) 2010-05-15 2018-12-25 Rai Strategic Holdings, Inc. Assembly directed airflow
US8757147B2 (en) 2010-05-15 2014-06-24 Minusa Holdings Llc Personal vaporizing inhaler with internal light source
US9259035B2 (en) 2010-05-15 2016-02-16 R. J. Reynolds Tobacco Company Solderless personal vaporizing inhaler
US9861772B2 (en) 2010-05-15 2018-01-09 Rai Strategic Holdings, Inc. Personal vaporizing inhaler cartridge
US9999250B2 (en) 2010-05-15 2018-06-19 Rai Strategic Holdings, Inc. Vaporizer related systems, methods, and apparatus
US9743691B2 (en) 2010-05-15 2017-08-29 Rai Strategic Holdings, Inc. Vaporizer configuration, control, and reporting
CN102553039B (zh) * 2010-12-17 2014-10-29 陈庆堂 药粉吸嘴及应用
US9078473B2 (en) 2011-08-09 2015-07-14 R.J. Reynolds Tobacco Company Smoking articles and use thereof for yielding inhalation materials
US20130255702A1 (en) 2012-03-28 2013-10-03 R.J. Reynolds Tobacco Company Smoking article incorporating a conductive substrate
US10004259B2 (en) 2012-06-28 2018-06-26 Rai Strategic Holdings, Inc. Reservoir and heater system for controllable delivery of multiple aerosolizable materials in an electronic smoking article
US8881737B2 (en) 2012-09-04 2014-11-11 R.J. Reynolds Tobacco Company Electronic smoking article comprising one or more microheaters
US8910639B2 (en) 2012-09-05 2014-12-16 R. J. Reynolds Tobacco Company Single-use connector and cartridge for a smoking article and related method
US9854841B2 (en) 2012-10-08 2018-01-02 Rai Strategic Holdings, Inc. Electronic smoking article and associated method
US10117460B2 (en) 2012-10-08 2018-11-06 Rai Strategic Holdings, Inc. Electronic smoking article and associated method
US8910640B2 (en) 2013-01-30 2014-12-16 R.J. Reynolds Tobacco Company Wick suitable for use in an electronic smoking article
US10031183B2 (en) 2013-03-07 2018-07-24 Rai Strategic Holdings, Inc. Spent cartridge detection method and system for an electronic smoking article
US9277770B2 (en) 2013-03-14 2016-03-08 R. J. Reynolds Tobacco Company Atomizer for an aerosol delivery device formed from a continuously extending wire and related input, cartridge, and method
US9918495B2 (en) 2014-02-28 2018-03-20 Rai Strategic Holdings, Inc. Atomizer for an aerosol delivery device and related input, aerosol production assembly, cartridge, and method
US9609893B2 (en) 2013-03-15 2017-04-04 Rai Strategic Holdings, Inc. Cartridge and control body of an aerosol delivery device including anti-rotation mechanism and related method
US9220302B2 (en) 2013-03-15 2015-12-29 R.J. Reynolds Tobacco Company Cartridge for an aerosol delivery device and method for assembling a cartridge for a smoking article
US9423152B2 (en) 2013-03-15 2016-08-23 R. J. Reynolds Tobacco Company Heating control arrangement for an electronic smoking article and associated system and method
US9491974B2 (en) 2013-03-15 2016-11-15 Rai Strategic Holdings, Inc. Heating elements formed from a sheet of a material and inputs and methods for the production of atomizers
US11229239B2 (en) 2013-07-19 2022-01-25 Rai Strategic Holdings, Inc. Electronic smoking article with haptic feedback
US10172387B2 (en) 2013-08-28 2019-01-08 Rai Strategic Holdings, Inc. Carbon conductive substrate for electronic smoking article
US10292424B2 (en) 2013-10-31 2019-05-21 Rai Strategic Holdings, Inc. Aerosol delivery device including a pressure-based aerosol delivery mechanism
US9839237B2 (en) 2013-11-22 2017-12-12 Rai Strategic Holdings, Inc. Reservoir housing for an electronic smoking article
US9974334B2 (en) 2014-01-17 2018-05-22 Rai Strategic Holdings, Inc. Electronic smoking article with improved storage of aerosol precursor compositions
US10575558B2 (en) 2014-02-03 2020-03-03 Rai Strategic Holdings, Inc. Aerosol delivery device comprising multiple outer bodies and related assembly method
US9451791B2 (en) 2014-02-05 2016-09-27 Rai Strategic Holdings, Inc. Aerosol delivery device with an illuminated outer surface and related method
US20150224268A1 (en) 2014-02-07 2015-08-13 R.J. Reynolds Tobacco Company Charging Accessory Device for an Aerosol Delivery Device and Related System, Method, Apparatus, and Computer Program Product for Providing Interactive Services for Aerosol Delivery Devices
US9833019B2 (en) 2014-02-13 2017-12-05 Rai Strategic Holdings, Inc. Method for assembling a cartridge for a smoking article
US9839238B2 (en) 2014-02-28 2017-12-12 Rai Strategic Holdings, Inc. Control body for an electronic smoking article
US9597466B2 (en) 2014-03-12 2017-03-21 R. J. Reynolds Tobacco Company Aerosol delivery system and related method, apparatus, and computer program product for providing control information to an aerosol delivery device via a cartridge
US11696604B2 (en) 2014-03-13 2023-07-11 Rai Strategic Holdings, Inc. Aerosol delivery device and related method and computer program product for controlling an aerosol delivery device based on input characteristics
US9877510B2 (en) 2014-04-04 2018-01-30 Rai Strategic Holdings, Inc. Sensor for an aerosol delivery device
US9924741B2 (en) 2014-05-05 2018-03-27 Rai Strategic Holdings, Inc. Method of preparing an aerosol delivery device
US9955726B2 (en) 2014-05-23 2018-05-01 Rai Strategic Holdings, Inc. Sealed cartridge for an aerosol delivery device and related assembly method
US10888119B2 (en) 2014-07-10 2021-01-12 Rai Strategic Holdings, Inc. System and related methods, apparatuses, and computer program products for controlling operation of a device based on a read request
US10058123B2 (en) 2014-07-11 2018-08-28 R. J. Reynolds Tobacco Company Heater for an aerosol delivery device and methods of formation thereof
US10765144B2 (en) 2014-08-21 2020-09-08 Rai Strategic Holdings, Inc. Aerosol delivery device including a moveable cartridge and related assembly method
US9609895B2 (en) 2014-08-21 2017-04-04 Rai Strategic Holdings, Inc. System and related methods, apparatuses, and computer program products for testing components of an aerosol delivery device
US9913493B2 (en) 2014-08-21 2018-03-13 Rai Strategic Holdings, Inc. Aerosol delivery device including a moveable cartridge and related assembly method
US11051554B2 (en) 2014-11-12 2021-07-06 Rai Strategic Holdings, Inc. MEMS-based sensor for an aerosol delivery device
US10500600B2 (en) 2014-12-09 2019-12-10 Rai Strategic Holdings, Inc. Gesture recognition user interface for an aerosol delivery device
US10321711B2 (en) 2015-01-29 2019-06-18 Rai Strategic Holdings, Inc. Proximity detection for an aerosol delivery device
US10027016B2 (en) 2015-03-04 2018-07-17 Rai Strategic Holdings Inc. Antenna for an aerosol delivery device
US9980516B2 (en) 2015-03-09 2018-05-29 Rai Strategic Holdings, Inc. Aerosol delivery device including a wave guide and related method
US10172388B2 (en) 2015-03-10 2019-01-08 Rai Strategic Holdings, Inc. Aerosol delivery device with microfluidic delivery component
US11000069B2 (en) 2015-05-15 2021-05-11 Rai Strategic Holdings, Inc. Aerosol delivery device and methods of formation thereof
US10238145B2 (en) 2015-05-19 2019-03-26 Rai Strategic Holdings, Inc. Assembly substation for assembling a cartridge for a smoking article
US11504489B2 (en) 2015-07-17 2022-11-22 Rai Strategic Holdings, Inc. Contained liquid system for refilling aerosol delivery devices
US10966460B2 (en) 2015-07-17 2021-04-06 Rai Strategic Holdings, Inc. Load-based detection of an aerosol delivery device in an assembled arrangement
US11134544B2 (en) 2015-07-24 2021-09-28 Rai Strategic Holdings, Inc. Aerosol delivery device with radiant heating
US11033054B2 (en) 2015-07-24 2021-06-15 Rai Strategic Holdings, Inc. Radio-frequency identification (RFID) authentication system for aerosol delivery devices
US10015987B2 (en) 2015-07-24 2018-07-10 Rai Strategic Holdings Inc. Trigger-based wireless broadcasting for aerosol delivery devices
US10206429B2 (en) 2015-07-24 2019-02-19 Rai Strategic Holdings, Inc. Aerosol delivery device with radiant heating
US10058125B2 (en) 2015-10-13 2018-08-28 Rai Strategic Holdings, Inc. Method for assembling an aerosol delivery device
US10582726B2 (en) 2015-10-21 2020-03-10 Rai Strategic Holdings, Inc. Induction charging for an aerosol delivery device
US20170112194A1 (en) 2015-10-21 2017-04-27 Rai Strategic Holdings, Inc. Rechargeable lithium-ion capacitor for an aerosol delivery device
US10918134B2 (en) 2015-10-21 2021-02-16 Rai Strategic Holdings, Inc. Power supply for an aerosol delivery device
US10201187B2 (en) 2015-11-02 2019-02-12 Rai Strategic Holdings, Inc. User interface for an aerosol delivery device
US10820630B2 (en) 2015-11-06 2020-11-03 Rai Strategic Holdings, Inc. Aerosol delivery device including a wirelessly-heated atomizer and related method
US9955733B2 (en) 2015-12-07 2018-05-01 Rai Strategic Holdings, Inc. Camera for an aerosol delivery device
US10440992B2 (en) 2015-12-07 2019-10-15 Rai Strategic Holdings, Inc. Motion sensing for an aerosol delivery device
US11291252B2 (en) 2015-12-18 2022-04-05 Rai Strategic Holdings, Inc. Proximity sensing for an aerosol delivery device
US10092036B2 (en) 2015-12-28 2018-10-09 Rai Strategic Holdings, Inc. Aerosol delivery device including a housing and a coupler
US10194694B2 (en) 2016-01-05 2019-02-05 Rai Strategic Holdings, Inc. Aerosol delivery device with improved fluid transport
US10051891B2 (en) 2016-01-05 2018-08-21 Rai Strategic Holdings, Inc. Capacitive sensing input device for an aerosol delivery device
US10258086B2 (en) 2016-01-12 2019-04-16 Rai Strategic Holdings, Inc. Hall effect current sensor for an aerosol delivery device
US10104912B2 (en) 2016-01-20 2018-10-23 Rai Strategic Holdings, Inc. Control for an induction-based aerosol delivery device
US10015989B2 (en) 2016-01-27 2018-07-10 Rai Strategic Holdings, Inc. One-way valve for refilling an aerosol delivery device
US11412781B2 (en) 2016-02-12 2022-08-16 Rai Strategic Holdings, Inc. Adapters for refilling an aerosol delivery device
US9936733B2 (en) 2016-03-09 2018-04-10 Rai Strategic Holdings, Inc. Accessory configured to charge an aerosol delivery device and related method
US10334880B2 (en) 2016-03-25 2019-07-02 Rai Strategic Holdings, Inc. Aerosol delivery device including connector comprising extension and receptacle
US11207478B2 (en) 2016-03-25 2021-12-28 Rai Strategic Holdings, Inc. Aerosol production assembly including surface with micro-pattern
US10945462B2 (en) 2016-04-12 2021-03-16 Rai Strategic Holdings, Inc. Detachable power source for an aerosol delivery device
US10333339B2 (en) 2016-04-12 2019-06-25 Rai Strategic Holdings, Inc. Charger for an aerosol delivery device
US10028534B2 (en) 2016-04-20 2018-07-24 Rai Strategic Holdings, Inc. Aerosol delivery device, and associated apparatus and method of formation thereof
US10405579B2 (en) 2016-04-29 2019-09-10 Rai Strategic Holdings, Inc. Methods for assembling a cartridge for an aerosol delivery device, and associated systems and apparatuses
US10959458B2 (en) 2016-06-20 2021-03-30 Rai Strategic Holdings, Inc. Aerosol delivery device including an electrical generator assembly
US10085485B2 (en) 2016-07-06 2018-10-02 Rai Strategic Holdings, Inc. Aerosol delivery device with a reservoir housing and a vaporizer assembly
US10405581B2 (en) 2016-07-08 2019-09-10 Rai Strategic Holdings, Inc. Gas sensing for an aerosol delivery device
US10463078B2 (en) 2016-07-08 2019-11-05 Rai Strategic Holdings, Inc. Aerosol delivery device with condensing and non-condensing vaporization
US10231485B2 (en) 2016-07-08 2019-03-19 Rai Strategic Holdings, Inc. Radio frequency to direct current converter for an aerosol delivery device
US10617151B2 (en) 2016-07-21 2020-04-14 Rai Strategic Holdings, Inc. Aerosol delivery device with a liquid transport element comprising a porous monolith and related method
US10602775B2 (en) 2016-07-21 2020-03-31 Rai Strategic Holdings, Inc. Aerosol delivery device with a unitary reservoir and liquid transport element comprising a porous monolith and related method
US11019847B2 (en) 2016-07-28 2021-06-01 Rai Strategic Holdings, Inc. Aerosol delivery devices including a selector and related methods
US10765146B2 (en) 2016-08-08 2020-09-08 Rai Strategic Holdings, Inc. Boost converter for an aerosol delivery device
US11937647B2 (en) 2016-09-09 2024-03-26 Rai Strategic Holdings, Inc. Fluidic control for an aerosol delivery device
US10080387B2 (en) 2016-09-23 2018-09-25 Rai Strategic Holdings, Inc. Aerosol delivery device with replaceable wick and heater assembly
US10477896B2 (en) 2016-10-12 2019-11-19 Rai Strategic Holdings, Inc. Photodetector for measuring aerosol precursor composition in an aerosol delivery device
US10524508B2 (en) 2016-11-15 2020-01-07 Rai Strategic Holdings, Inc. Induction-based aerosol delivery device
US9864947B1 (en) 2016-11-15 2018-01-09 Rai Strategic Holdings, Inc. Near field communication for a tobacco-based article or package therefor
US10492530B2 (en) 2016-11-15 2019-12-03 Rai Strategic Holdings, Inc. Two-wire authentication system for an aerosol delivery device
US11103012B2 (en) 2016-11-17 2021-08-31 Rai Strategic Holdings, Inc. Satellite navigation for an aerosol delivery device
US10206431B2 (en) 2016-11-18 2019-02-19 Rai Strategic Holdings, Inc. Charger for an aerosol delivery device
US10653183B2 (en) 2016-11-18 2020-05-19 Rai Strategic Holdings, Inc. Power source for an aerosol delivery device
US10172392B2 (en) 2016-11-18 2019-01-08 Rai Strategic Holdings, Inc. Humidity sensing for an aerosol delivery device
US10524509B2 (en) 2016-11-18 2020-01-07 Rai Strategic Holdings, Inc. Pressure sensing for an aerosol delivery device
US10537137B2 (en) 2016-11-22 2020-01-21 Rai Strategic Holdings, Inc. Rechargeable lithium-ion battery for an aerosol delivery device
US11013266B2 (en) 2016-12-09 2021-05-25 Rai Strategic Holdings, Inc. Aerosol delivery device sensory system including an infrared sensor and related method
US10517326B2 (en) 2017-01-27 2019-12-31 Rai Strategic Holdings, Inc. Secondary battery for an aerosol delivery device
US10827783B2 (en) 2017-02-27 2020-11-10 Rai Strategic Holdings, Inc. Digital compass for an aerosol delivery device
US10314340B2 (en) 2017-04-21 2019-06-11 Rai Strategic Holdings, Inc. Refillable aerosol delivery device and related method
US11297876B2 (en) 2017-05-17 2022-04-12 Rai Strategic Holdings, Inc. Aerosol delivery device
US11589621B2 (en) 2017-05-23 2023-02-28 Rai Strategic Holdings, Inc. Heart rate monitor for an aerosol delivery device
US10517330B2 (en) 2017-05-23 2019-12-31 RAI Stategic Holdings, Inc. Heart rate monitor for an aerosol delivery device
US10842197B2 (en) 2017-07-12 2020-11-24 Rai Strategic Holdings, Inc. Detachable container for aerosol delivery having pierceable membrane
US10349674B2 (en) 2017-07-17 2019-07-16 Rai Strategic Holdings, Inc. No-heat, no-burn smoking article
US11337456B2 (en) 2017-07-17 2022-05-24 Rai Strategic Holdings, Inc. Video analytics camera system for an aerosol delivery device
US11039645B2 (en) 2017-09-19 2021-06-22 Rai Strategic Holdings, Inc. Differential pressure sensor for an aerosol delivery device
US10505383B2 (en) 2017-09-19 2019-12-10 Rai Strategic Holdings, Inc. Intelligent charger for an aerosol delivery device
US10660370B2 (en) 2017-10-12 2020-05-26 Rai Strategic Holdings, Inc. Aerosol delivery device including a control body, an atomizer body, and a cartridge and related methods
US10517332B2 (en) 2017-10-31 2019-12-31 Rai Strategic Holdings, Inc. Induction heated aerosol delivery device
US10806181B2 (en) 2017-12-08 2020-10-20 Rai Strategic Holdings, Inc. Quasi-resonant flyback converter for an induction-based aerosol delivery device
US10555558B2 (en) 2017-12-29 2020-02-11 Rai Strategic Holdings, Inc. Aerosol delivery device providing flavor control
US11019850B2 (en) 2018-02-26 2021-06-01 Rai Strategic Holdings, Inc. Heat conducting substrate for electrically heated aerosol delivery device
CN109805456B (zh) * 2019-03-26 2024-04-16 深圳市你我网络科技有限公司 一种雾化器及电子烟
CN110354346B (zh) * 2019-07-26 2021-09-14 郑州铁路职业技术学院 耳鼻喉护理药物雾化装置

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005099494A1 (fr) * 2004-04-14 2005-10-27 Lik Hon Cigarette electronique a aerosol
CN2777995Y (zh) * 2005-03-30 2006-05-10 韩力 雾化电子烟斗
WO2006078900A1 (fr) * 2005-01-19 2006-07-27 Aerogen, Inc. Procedes et dispositifs pour administrer un medicament en aerosol
CN2889333Y (zh) * 2006-05-24 2007-04-18 深圳市健康源科技有限公司 口吸式家用超声雾化治疗仪
CN2905088Y (zh) * 2006-04-10 2007-05-30 陈清甫 便携式雾化给药装置
CN101053685A (zh) * 2006-04-10 2007-10-17 陈清甫 便携式雾化给药装置
CN200966824Y (zh) * 2006-11-10 2007-10-31 韩力 吸入雾化装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005099494A1 (fr) * 2004-04-14 2005-10-27 Lik Hon Cigarette electronique a aerosol
WO2006078900A1 (fr) * 2005-01-19 2006-07-27 Aerogen, Inc. Procedes et dispositifs pour administrer un medicament en aerosol
CN2777995Y (zh) * 2005-03-30 2006-05-10 韩力 雾化电子烟斗
CN2905088Y (zh) * 2006-04-10 2007-05-30 陈清甫 便携式雾化给药装置
CN101053685A (zh) * 2006-04-10 2007-10-17 陈清甫 便携式雾化给药装置
CN2889333Y (zh) * 2006-05-24 2007-04-18 深圳市健康源科技有限公司 口吸式家用超声雾化治疗仪
CN200966824Y (zh) * 2006-11-10 2007-10-31 韩力 吸入雾化装置

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109985297A (zh) * 2019-05-17 2019-07-09 深圳市柏明胜医疗器械有限公司 一种药瓶
CN114832191A (zh) * 2022-04-12 2022-08-02 卜鹿生物技术(成都)有限公司 二次雾化装置及药物雾化系统
CN114832191B (zh) * 2022-04-12 2024-01-30 卜鹿生物技术(成都)有限公司 二次雾化装置及药物雾化系统

Also Published As

Publication number Publication date
CN101176805A (zh) 2008-05-14
CN100536951C (zh) 2009-09-09

Similar Documents

Publication Publication Date Title
WO2008058455A1 (fr) Dispositif d'administration d'un médicament pour affections pulmonaires
WO2008055423A1 (fr) Dispositif d'inhalation pulverisateur d'aerosol
US11672939B2 (en) Supplemental oxygen delivery system
CA2497871C (fr) Dispositifs de production d'aerosol et procedes de production d'aerosols a dimensions granulometriques regulees
EP2273933B1 (fr) Humidification de circuits respiratoires
WO2008117265A1 (fr) Humidification de circuits respiratoires
EP3806940B1 (fr) Système de vaporisation moléculaire d'une substance liquide
CN219148837U (zh) 一种即雾化即吸入式雾化给药装置
CN201543064U (zh) 一种超声雾化装置
CN113952562A (zh) 一种雾化器
CN216496899U (zh) 一种雾化器
CN110559527A (zh) 一种耳鼻咽喉科内使用的小型自动控制式超声波雾化器
CN201020127Y (zh) 一种肺内给药装置
KR102637927B1 (ko) 약물 분사 장치
CN110665097B (zh) 一种含有便携式医用雾化器及其配套的一次性给药器的系统
WO2024012194A1 (fr) Dispositif d'administration de médicament par atomisation de type à atomisation-inhalation
IE20090749A1 (en) A supplemental oxygen delivery system
IE20080243A1 (en) Humidifaction in breathing

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07816793

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTIFICATION OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 1205A SENT ON 24.08.09)

122 Ep: pct application non-entry in european phase

Ref document number: 07816793

Country of ref document: EP

Kind code of ref document: A1