WO2008055159A3 - Flash photolysis therapy for regulation of physiological function - Google Patents

Flash photolysis therapy for regulation of physiological function Download PDF

Info

Publication number
WO2008055159A3
WO2008055159A3 PCT/US2007/083009 US2007083009W WO2008055159A3 WO 2008055159 A3 WO2008055159 A3 WO 2008055159A3 US 2007083009 W US2007083009 W US 2007083009W WO 2008055159 A3 WO2008055159 A3 WO 2008055159A3
Authority
WO
WIPO (PCT)
Prior art keywords
therapy
photo
regulation
flash photolysis
reactive compound
Prior art date
Application number
PCT/US2007/083009
Other languages
French (fr)
Other versions
WO2008055159A4 (en
WO2008055159A2 (en
Inventor
Rodolphe P Katra
Original Assignee
Medtronic Inc
Rodolphe P Katra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc, Rodolphe P Katra filed Critical Medtronic Inc
Priority to EP07863660A priority Critical patent/EP2079523A2/en
Publication of WO2008055159A2 publication Critical patent/WO2008055159A2/en
Publication of WO2008055159A3 publication Critical patent/WO2008055159A3/en
Publication of WO2008055159A4 publication Critical patent/WO2008055159A4/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0622—Optical stimulation for exciting neural tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0042—Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3629—Heart stimulators in combination with non-electric therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Radiation-Therapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Flash photolysis therapy is used to enhance cellular function, such as abnormal myocardial or renal function. A photo-reactive compound is administered to cells requiring therapy. A light stimulus is applied to the photo-reactive compound to cause desired intracellular activity when the photo-reactive compound is activated. The activated compound can, for example, affect intracellular calcium concentration, to cause forced contraction or relaxation in the muscle tissue.
PCT/US2007/083009 2006-10-30 2007-10-30 Flash photolysis therapy for regulation of physiological function WO2008055159A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07863660A EP2079523A2 (en) 2006-10-30 2007-10-30 Flash photolysis therapy for regulation of physiological function

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86341906P 2006-10-30 2006-10-30
US60/863,419 2006-10-30

Publications (3)

Publication Number Publication Date
WO2008055159A2 WO2008055159A2 (en) 2008-05-08
WO2008055159A3 true WO2008055159A3 (en) 2008-10-30
WO2008055159A4 WO2008055159A4 (en) 2008-12-31

Family

ID=39345052

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/083009 WO2008055159A2 (en) 2006-10-30 2007-10-30 Flash photolysis therapy for regulation of physiological function

Country Status (2)

Country Link
EP (1) EP2079523A2 (en)
WO (1) WO2008055159A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8435276B2 (en) 2006-02-27 2013-05-07 Thomas Perez Method and apparatus for the combined application of light therapy, optic diagnosis, and fluid to tissue
GB0816501D0 (en) * 2008-09-10 2008-10-15 Imp Innovations Ltd Photo-ionic pacemakers
US8951296B2 (en) * 2012-06-29 2015-02-10 Medtronic Ardian Luxembourg S.A.R.L. Devices and methods for photodynamically modulating neural function in a human

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298018A (en) * 1992-08-14 1994-03-29 Pdt Cardiovascular, Inc. Method for treating cardiovascular disease through adjunctive photodynamic therapy
US5445608A (en) * 1993-08-16 1995-08-29 James C. Chen Method and apparatus for providing light-activated therapy
US6146410A (en) * 1995-11-24 2000-11-14 Nagypal; Tibor Apparatus for the photodynamic treatment of living beings or organs thereof
WO2002003872A2 (en) * 2000-07-11 2002-01-17 Johns Hopkins University Application of photochemotherapy for the treatment of cardiac arrhythmias
WO2002009610A1 (en) * 2000-07-31 2002-02-07 Epicor, Inc. Procedures for photodynamic cardiac ablation therapy and devices for those procedures
US20050101997A1 (en) * 2003-11-12 2005-05-12 Reddy Vivek Y. Arrangements and methods for determining or treating cardiac abnormalities and inconsistencies
US20070244524A1 (en) * 2006-04-12 2007-10-18 Jihong Qu Method and device for photoreactive therapy and diagnosis

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298018A (en) * 1992-08-14 1994-03-29 Pdt Cardiovascular, Inc. Method for treating cardiovascular disease through adjunctive photodynamic therapy
US5445608A (en) * 1993-08-16 1995-08-29 James C. Chen Method and apparatus for providing light-activated therapy
US6146410A (en) * 1995-11-24 2000-11-14 Nagypal; Tibor Apparatus for the photodynamic treatment of living beings or organs thereof
WO2002003872A2 (en) * 2000-07-11 2002-01-17 Johns Hopkins University Application of photochemotherapy for the treatment of cardiac arrhythmias
WO2002009610A1 (en) * 2000-07-31 2002-02-07 Epicor, Inc. Procedures for photodynamic cardiac ablation therapy and devices for those procedures
US20050101997A1 (en) * 2003-11-12 2005-05-12 Reddy Vivek Y. Arrangements and methods for determining or treating cardiac abnormalities and inconsistencies
US20070244524A1 (en) * 2006-04-12 2007-10-18 Jihong Qu Method and device for photoreactive therapy and diagnosis

Also Published As

Publication number Publication date
WO2008055159A4 (en) 2008-12-31
WO2008055159A2 (en) 2008-05-08
EP2079523A2 (en) 2009-07-22

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