WO2008043365A8 - Method and apparatus for assessing the level of nociception during the awake state and general anaesthesia by auditory evoked potentials (aep) - Google Patents

Method and apparatus for assessing the level of nociception during the awake state and general anaesthesia by auditory evoked potentials (aep)

Info

Publication number
WO2008043365A8
WO2008043365A8 PCT/DK2007/000442 DK2007000442W WO2008043365A8 WO 2008043365 A8 WO2008043365 A8 WO 2008043365A8 DK 2007000442 W DK2007000442 W DK 2007000442W WO 2008043365 A8 WO2008043365 A8 WO 2008043365A8
Authority
WO
WIPO (PCT)
Prior art keywords
aep
nociception
assessing
level
evoked potentials
Prior art date
Application number
PCT/DK2007/000442
Other languages
French (fr)
Other versions
WO2008043365A1 (en
Inventor
Erik Weber Jesen
Original Assignee
Danmeter As
Erik Weber Jesen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danmeter As, Erik Weber Jesen filed Critical Danmeter As
Priority to PCT/DK2007/000442 priority Critical patent/WO2008043365A1/en
Publication of WO2008043365A1 publication Critical patent/WO2008043365A1/en
Publication of WO2008043365A8 publication Critical patent/WO2008043365A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4821—Determining level or depth of anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A61B5/377—Electroencephalography [EEG] using evoked responses
    • A61B5/38—Acoustic or auditory stimuli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems

Abstract

In order to guide the administration of analgesic drugs to a patient under anaesthesia, a method an and apparatus for assessing the level of nociception by calculating an index of nociception based on measurements of Auditory Evoked Potentials (AEP) is applied. Several parameters derived from the AEP signals are used as an input for an Adaptive Neuro Fuzzy Inference System (ANFIS) that calculates an index of nociception represented in a scale from 40 to 0, where a value of 40 means high sensitivity to noxious stimuli while a decreasing index means a lower sensitivity to noxious stimulation.
PCT/DK2007/000442 2006-10-12 2007-10-25 Method and apparatus for assessing the level of nociception during the awake state and general anaesthesia by auditory evoked potentials (aep) WO2008043365A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/DK2007/000442 WO2008043365A1 (en) 2006-10-12 2007-10-25 Method and apparatus for assessing the level of nociception during the awake state and general anaesthesia by auditory evoked potentials (aep)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200601324 2006-10-12
PCT/DK2007/000442 WO2008043365A1 (en) 2006-10-12 2007-10-25 Method and apparatus for assessing the level of nociception during the awake state and general anaesthesia by auditory evoked potentials (aep)

Publications (2)

Publication Number Publication Date
WO2008043365A1 WO2008043365A1 (en) 2008-04-17
WO2008043365A8 true WO2008043365A8 (en) 2008-11-27

Family

ID=38819278

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2007/000442 WO2008043365A1 (en) 2006-10-12 2007-10-25 Method and apparatus for assessing the level of nociception during the awake state and general anaesthesia by auditory evoked potentials (aep)

Country Status (1)

Country Link
WO (1) WO2008043365A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5710767B2 (en) 2010-09-28 2015-04-30 マシモ コーポレイション Depth of consciousness monitor including oximeter
US9775545B2 (en) 2010-09-28 2017-10-03 Masimo Corporation Magnetic electrical connector for patient monitors
WO2014091291A1 (en) * 2012-12-11 2014-06-19 MARUGG, James A device and method for determining the probability of response to pain and nociception of a subject t
WO2014111554A1 (en) * 2013-01-17 2014-07-24 Sensodetect Ab Method and system for monitoring depth of anaesthesia and sensory functioning
CN105144177B (en) 2013-04-24 2019-05-28 费森尤斯卡比德国有限公司 A kind of control device controlled for the infusion device to patient's dispensing drug
CN104138257A (en) * 2014-07-17 2014-11-12 南宁市锋威科技有限公司 Surgical anesthesia pain perception monitor
WO2016057553A1 (en) 2014-10-07 2016-04-14 Masimo Corporation Modular physiological sensors
CN105536094A (en) * 2016-02-02 2016-05-04 钱浩 Intelligent monitoring type operative anesthesia system
NL2020601B1 (en) * 2018-03-16 2019-09-26 Stichting Vu Method of determining brain activity
CN115068823B (en) * 2022-08-19 2022-11-15 江西华恒京兴医疗科技有限公司 Individualized transcranial direct current stimulation current intensity threshold detection system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618998D0 (en) * 1996-09-11 1996-10-23 Univ Glasgow Anaesthesia control
US7089927B2 (en) * 2002-10-23 2006-08-15 New York University System and method for guidance of anesthesia, analgesia and amnesia
WO2004054441A1 (en) * 2002-12-13 2004-07-01 Danmeter A/S Methods of evaluating the level of consciousness using aep eeg and anfis

Also Published As

Publication number Publication date
WO2008043365A1 (en) 2008-04-17

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