WO2008040771A3 - Verfahren und anordnung zur charakterisierung eines objekts mit licht und scherbewegung - Google Patents

Verfahren und anordnung zur charakterisierung eines objekts mit licht und scherbewegung Download PDF

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Publication number
WO2008040771A3
WO2008040771A3 PCT/EP2007/060522 EP2007060522W WO2008040771A3 WO 2008040771 A3 WO2008040771 A3 WO 2008040771A3 EP 2007060522 W EP2007060522 W EP 2007060522W WO 2008040771 A3 WO2008040771 A3 WO 2008040771A3
Authority
WO
WIPO (PCT)
Prior art keywords
light
charactization
arrangement
shear
speckle
Prior art date
Application number
PCT/EP2007/060522
Other languages
English (en)
French (fr)
Other versions
WO2008040771A2 (de
WO2008040771B1 (de
Inventor
Arik Funke
Claude Boccara
Emmanuel Bossy
Mathias Fink
Mickael Tanter
Original Assignee
Arik Funke
Claude Boccara
Emmanuel Bossy
Mathias Fink
Mickael Tanter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arik Funke, Claude Boccara, Emmanuel Bossy, Mathias Fink, Mickael Tanter filed Critical Arik Funke
Publication of WO2008040771A2 publication Critical patent/WO2008040771A2/de
Publication of WO2008040771A3 publication Critical patent/WO2008040771A3/de
Publication of WO2008040771B1 publication Critical patent/WO2008040771B1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0097—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying acoustic waves and detecting light, i.e. acoustooptic measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
    • A61B5/0051—Detecting, measuring or recording by applying mechanical forces or stimuli by applying vibrations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/04—Analysing solids
    • G01N29/06—Visualisation of the interior, e.g. acoustic microscopy
    • G01N29/0654—Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G01N29/24—Probes
    • G01N29/2418—Probes using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/34—Generating the ultrasonic, sonic or infrasonic waves, e.g. electronic circuits specially adapted therefor
    • G01N29/341—Generating the ultrasonic, sonic or infrasonic waves, e.g. electronic circuits specially adapted therefor with time characteristics
    • G01N29/343—Generating the ultrasonic, sonic or infrasonic waves, e.g. electronic circuits specially adapted therefor with time characteristics pulse waves, e.g. particular sequence of pulses, bursts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G01N2021/1727—Magnetomodulation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/024—Mixtures
    • G01N2291/02475—Tissue characterisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/028—Material parameters
    • G01N2291/02827—Elastic parameters, strength or force

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Acoustics & Sound (AREA)
  • Optics & Photonics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement Of Mechanical Vibrations Or Ultrasonic Waves (AREA)
  • Length Measuring Devices By Optical Means (AREA)

Abstract

Untersuchungslicht L wird in ein Objekt 1 gesendet. Das Untersuchungslicht L wird nach Durchlaufen des Objekts 2 als Laser-Speckle I detektiert. Ein fokussierter Ultraschallpuls U mit einigen Hundert Oszillationen wird in das Objekt 1 gesendet und dessen akustische Strahlkraft (engl. acoustic radiation force) führt zu Scherung im Objekt 1. Als Folge der Scherung im Objekt 1 ändert sich das detektierte Speckle I. Aus der Korrelation des Speckle I werden Informationen für einen Bildpunkt zur Abbildung der optischen und mechanischen Eigenschaften des Objekts 1 erhalten.
PCT/EP2007/060522 2006-10-05 2007-10-03 Verfahren und anordnung zur charakterisierung eines objekts mit licht und scherbewegung WO2008040771A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006047476A DE102006047476A1 (de) 2006-10-05 2006-10-05 Verfahren und Anordnung zum Abbilden eines Objekts mit Licht und Scherkräften
DE102006047476.7 2006-10-05

Publications (3)

Publication Number Publication Date
WO2008040771A2 WO2008040771A2 (de) 2008-04-10
WO2008040771A3 true WO2008040771A3 (de) 2008-08-14
WO2008040771B1 WO2008040771B1 (de) 2008-10-30

Family

ID=39184751

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/060522 WO2008040771A2 (de) 2006-10-05 2007-10-03 Verfahren und anordnung zur charakterisierung eines objekts mit licht und scherbewegung

Country Status (2)

Country Link
DE (1) DE102006047476A1 (de)
WO (1) WO2008040771A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0818775D0 (en) 2008-10-13 2008-11-19 Isis Innovation Investigation of physical properties of an object
GB201116518D0 (en) 2011-09-23 2011-11-09 Isis Innovation Investigation of physical properties of an object
US10016137B1 (en) 2017-11-22 2018-07-10 Hi Llc System and method for simultaneously detecting phase modulated optical signals
US10420469B2 (en) 2017-11-22 2019-09-24 Hi Llc Optical detection system for determining neural activity in brain based on water concentration
US10368752B1 (en) 2018-03-08 2019-08-06 Hi Llc Devices and methods to convert conventional imagers into lock-in cameras
US11206985B2 (en) 2018-04-13 2021-12-28 Hi Llc Non-invasive optical detection systems and methods in highly scattering medium
US11857316B2 (en) 2018-05-07 2024-01-02 Hi Llc Non-invasive optical detection system and method

Citations (3)

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Publication number Priority date Publication date Assignee Title
US5212667A (en) * 1992-02-03 1993-05-18 General Electric Company Light imaging in a scattering medium, using ultrasonic probing and speckle image differencing
US20040077949A1 (en) * 2001-01-11 2004-04-22 Blofgett David W. Assessment of tooth structure using laser based ultrasonics
US20040099815A1 (en) * 2000-07-23 2004-05-27 Sfez Bruno Gad Apparatus and method for probing light absorbing agents in biological tissues

Family Cites Families (4)

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US4762413A (en) * 1984-09-07 1988-08-09 Olympus Optical Co., Ltd. Method and apparatus for measuring immunological reaction with the aid of fluctuation in intensity of scattered light
US4633715A (en) * 1985-05-08 1987-01-06 Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee Laser heterodyne interferometric method and system for measuring ultrasonic displacements
FR2617602B1 (fr) 1987-07-03 1989-10-20 Thomson Csf Procede et systeme d'imagerie par transillumination a marquage en frequence des photons
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5212667A (en) * 1992-02-03 1993-05-18 General Electric Company Light imaging in a scattering medium, using ultrasonic probing and speckle image differencing
US20040099815A1 (en) * 2000-07-23 2004-05-27 Sfez Bruno Gad Apparatus and method for probing light absorbing agents in biological tissues
US20040077949A1 (en) * 2001-01-11 2004-04-22 Blofgett David W. Assessment of tooth structure using laser based ultrasonics

Non-Patent Citations (5)

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Title
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REMENIERAS J-P ET AL: "Acoustic pressure measurement by acousto-optic tomography", 2001 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS. ATLANTA, GA, OCT. 7 - 10, 2001; [IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS], NEW YORK, NY : IEEE, US, vol. 1, 7 October 2001 (2001-10-07), pages 505 - 508, XP010584573, ISBN: 978-0-7803-7177-4 *
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Also Published As

Publication number Publication date
DE102006047476A1 (de) 2008-04-17
WO2008040771A2 (de) 2008-04-10
WO2008040771B1 (de) 2008-10-30

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