WO2008037045A3 - Composition containing a mixture of antidepressants for treating premature ejaculation. - Google Patents
Composition containing a mixture of antidepressants for treating premature ejaculation. Download PDFInfo
- Publication number
- WO2008037045A3 WO2008037045A3 PCT/BR2007/000262 BR2007000262W WO2008037045A3 WO 2008037045 A3 WO2008037045 A3 WO 2008037045A3 BR 2007000262 W BR2007000262 W BR 2007000262W WO 2008037045 A3 WO2008037045 A3 WO 2008037045A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- premature ejaculation
- treatment
- antidepressant
- antidepressants
- mixture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Abstract
The present invention refers to the combined use of antidepressant agents for the treatment of masculine sexual dysfunction, particularly premature ejaculation, considering that the combinations can comprise a Tricyclic Antidepressant (TCA), a Tetracyclic Antidepressant (TeCA), a Selective Serotonin Reuptake Inhibitor (SSRI), and optionally a Serotonin - Norepinefrine Reuptake Inhibitor (SNRI), in pharmaceutical forms offering bioavailability below the conventional doses used for these antidepressant agents, for the treatment of clinical settings of depression. These combinations allow the treatment of premature ejaculation, increasing the Intravaginal Ejaculation Latency Time for a time above 3 minutes, without the occurrence of adverse side effects.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07815704A EP2089022A4 (en) | 2006-09-28 | 2007-09-28 | Composition containing a mixture of antidepressants for treating premature ejaculation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0604425-5 | 2006-09-28 | ||
BRPI0604425 | 2006-09-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008037045A2 WO2008037045A2 (en) | 2008-04-03 |
WO2008037045A3 true WO2008037045A3 (en) | 2008-05-15 |
Family
ID=39230554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/BR2007/000262 WO2008037045A2 (en) | 2006-09-28 | 2007-09-28 | Composition containing a mixture of antidepressants for treating premature ejaculation. |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2089022A4 (en) |
WO (1) | WO2008037045A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2722845A1 (en) | 2008-05-19 | 2009-11-26 | Yuhan Corporation | Pharmaceutical composition for the treatment of premature ejaculation |
US20160045454A1 (en) * | 2014-08-12 | 2016-02-18 | Tianxin Wang | Therapeutical methods, formulations and nutraceutical formulations |
WO2018102233A1 (en) * | 2016-11-30 | 2018-06-07 | Wang tian xin | Therapeutical methods, formulations and nutraceutical formulations |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922341A (en) * | 1997-10-28 | 1999-07-13 | Vivus, Incorporated | Local administration of pharmacologically active agents to treat premature ejaculation |
WO2002041883A2 (en) * | 2000-11-21 | 2002-05-30 | Vivus, Inc. | As-needed administration of tricyclic and other non-sri antidepressant drugs to treat premature ejaculation |
WO2005004855A1 (en) * | 2003-07-11 | 2005-01-20 | Worldwide Pe Patent Holdco Pty Ltd | Treatment of premature ejaculation |
-
2007
- 2007-09-28 EP EP07815704A patent/EP2089022A4/en not_active Withdrawn
- 2007-09-28 WO PCT/BR2007/000262 patent/WO2008037045A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922341A (en) * | 1997-10-28 | 1999-07-13 | Vivus, Incorporated | Local administration of pharmacologically active agents to treat premature ejaculation |
WO2002041883A2 (en) * | 2000-11-21 | 2002-05-30 | Vivus, Inc. | As-needed administration of tricyclic and other non-sri antidepressant drugs to treat premature ejaculation |
WO2005004855A1 (en) * | 2003-07-11 | 2005-01-20 | Worldwide Pe Patent Holdco Pty Ltd | Treatment of premature ejaculation |
Non-Patent Citations (1)
Title |
---|
See also references of EP2089022A4 * |
Also Published As
Publication number | Publication date |
---|---|
EP2089022A4 (en) | 2012-12-26 |
EP2089022A2 (en) | 2009-08-19 |
WO2008037045A2 (en) | 2008-04-03 |
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